Efficient inhibition of class A and class D β-lactamases by Michaelis complexes

Journal of Biological Chemistry

Volumn 282, Issue 30, 2007, Pages 21588-21591

  Kalp, Matthew ^a   Sheri, Anjaneyulu ^d   Buynak, John D ^d   Bethel, Christopher R ^c   Bonomo, Robert A ^b,c   Carey, Paul R ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^d SOUTHERN METHODIST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTAMASES; MICHAELIS COMPLEXES; RAMAN SIGNATURES;

ACYLATION; BACTERIA; DATA REDUCTION; RAMAN SPECTROSCOPY; REACTION KINETICS; SINGLE CRYSTALS;

ENZYME INHIBITION;

6 ALKYLIDIENE PENAM SULFONE; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; OXA 1 ENZYME; PIPERACILLIN; SA 1 204; SHV 1 ENZYME; TAZOBACTAM; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ANALYSIS; ENZYME MECHANISM; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; RAMAN SPECTROMETRY;

ACYLATION; BETA-LACTAMASES; BINDING SITES; CRYSTALLOGRAPHY; KINETICS; SERINE; SPECTRUM ANALYSIS, RAMAN;

BACTERIA (MICROORGANISMS);

EID: 34547590605     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C700080200     Document Type: Article

References (19)

1. Fisher, J. F., Meroueh, S. O., and Mobashery, S. (2005) Chem. Rev 105, 395-424
2. Page, M. G. (2000) Drug. Resist. Updat. 3, 109-125
3. Nukaga, M., Kumar, S., Nukaga, K., Pratt, R. F., and Knox, J. R. (2004) J. Biol. Chem. 279, 9344-9352
4. Chen, Y., Minasov, G., Roth, T. A., Prati, F., and Shoichet, B. K. (2006) J. Am. Chem. Soc. 128, 2970-2976
5. Powers, R. A., Morandi, F., and Shoichet, B. K. (2002) Structure (Lond.) 10, 1013-1023
6. Tondi, D., Morandi, F., Bonnet, R., Costi, M. P., and Shoichet, B. K. (2005) J. Am. Chem. Soc. 127, 4632-4639
7. Stubbs, K. A., Balcewich, M., Mark, B. L., and Vocadlo, D. J. (2007) J. Biol. Chem.
8. Buynak, J. D., Rao, A. S., Doppalapudi, V. R., Adam, G., Petersen, P. J., and Nidamarthy, S. D. (1999) Bioorg. Med. Chem. Lett. 9, 1997-2002
9. Helfand, M. S., Hujer, A. M., Sonnichsen, F. D., and Bonomo, R. A. (2002) J. Biol. Chem. 277, 47719-47723
10. Kuzin, A. P., Nukaga, M., Nukaga, Y., Hujer, A. M., Bonomo, R. A., and Knox, J. R. (1999) Biochemistry 38, 5720-5727
11. Sun, T., Nukaga, M., Mayama, K., Braswell, E. H., and Knox, J. R. (2003) Protein. Sci. 12, 82-91
12. Altose, M. D., Zheng, Y., Dong, J., Palfey, B. A., and Carey, P. R. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3006-3011
13. Dong, J., Swift, K., Matayoshi, E., Nienaber, V. L., Weitzberg, M., Rockway, T., and Carey, P. R. (2001) Biochemistry 40, 9751-9757
14. Frisch, A., Frisch, M. J., and Trucks, G. W. (2003) Gaussian 03. In., Gaussian, Inc., Wallingford, CT
15. Helfand, M. S., Totir, M. A., Carey, M. P., Hujer, A. M., Bonomo, R. A., and Carey, P. R. (2003) Biochemistry 42, 13386-13392
16. Totir, M. A., Padayatti, P. S., Helfand, M. S., Carey, M. P., Bonomo, R. A., Carey, P. R., and van den Akker, F. (2006) Biochemistry 45, 11895-11904
17. Crichlow, G. V., Nukaga, M., Doppalapudi, V. R., Buynak, J. D., and Knox, J. R. (2001) Biochemistry 40, 6233-6239
18. Venkatesan, A. M., Agarwal, A., Abe, T., Ushirogochi, H., Yamamura, I., Ado, M., Tsuyoshi, T., Dos Santos, O., Gu, Y., Sum, F. W., Li, Z., Francisco, G., Lin, Y. I., Petersen, P. J., Yang, Y., Kumagai, T., Weiss, W. J., Shlaes, D. M., Knox, J. R., and Mansour, T. S. (2006) J. Med. Chem. 49, 4623-4637
19. Venkatesan, A. M., Gu, Y., Dos Santos, O., Abe, T., Agarwal, A., Yang, Y., Petersen, P. J., Weiss, W. J., Mansour, T. S., Nukaga, M., Hujer, A. M., Bonomo, R. A., and Knox, J. R. (2004) J. Med. Chem. 47, 6556-6568