ZNF435, a novel human SCAN-containing zinc finger protein, inhibits AP-1-mediated transcriptional activation

Molecules and Cells

Volumn 23, Issue 3, 2007, Pages 316-322

  Gu, Xing ^a   Zheng, Mei ^a   Fei, Xiangwei ^a   Yang, Zhenxing ^a   Li, Fan ^a   Ji, Chaomeng ^a   Xie, Yi ^a   Mao, Yumin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

AP 1; C2H2 zinc finger protein; Homo association; MAPK signaling pathway; SCAN domain; Transcriptional suppressor

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; TRANSCRIPTION FACTOR AP 1; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; GENE ISOLATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VERTEBRATE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELLS, CULTURED; DIMERIZATION; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSFECTION; ZINC FINGERS;

VERTEBRATA;

EID: 34547534846     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Adachi, H. and Tsujimoto, M. (2002) Characterization of the human gene encoding the scavenger receptor expressed by endothelial cell and its regulation by a novel transcription factor, endothelial zinc finger protein-2. J Biol. Chem. 277, 24014-24021.
2. Adachi, M., Fukuda, M., and Nishida, E. (2000) Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J. Cell Biol. 148, 849-856.
3. Attar, R. M. and Gilman, M. Z. (1992) Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. MoL Cell. Biol. 12, 2432-2443.
4. Barlow, P. N., Luisi, B., Milner, A., and Everett, R. (1994) Structure of the C3H4domain by H-nuclear magnetic resonance spectroscopy. A new structural class of zinc-finger. J. Mot Biol. 237, 201-211.
5. Borden, K. L. and Freemont, P. S. (1996) The RING finger domain: a recent example of a sequence-structure family. Curr.Opin. Struct. Biol. 6,395-401.
6. Chang, L. and Karin, M. (2001) Mammalian MAP kinase signaling cascades. Nature 410, 211-218.
7. Collins, T., Stone, J. R., and Williams, A. J. (2001) All in the family: the BTB/POZ, KRAB, and SCAN domains. Mol.Cell. Biol. 21, 3609-3615.
8. Edelstein, L. C. and Collins, T. (2005) The SCAN domain family of zinc finger transcription factors. Gene 359, 1-17.
9. Gonsky, R., Knauf, J. A., Elisei, R., Wang, J. W., Su, S., et al. (1997) Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets. Nucleic Acids Res. 25, 3823-3831.
10. Gou, D. M., Sun, Y., Gao, L., Chow, L. M., Huang, J., et al. (2001) Cloning and characterization of a novel Kruppel-like zinc finger gene, ZNF268, expressed in early human embryo. Biochim. Biophys. Acta 1518, 306-310.
11. Hammarstrom, A., Berndt, K. D., Sillard, R., Adermann, K., and Otting, G. (1996) Solution structure of a naturally-occurring zinc-peptide complex demonstrates that the N-terminal zinc-binding module of the Lasp-1 LIM domain is an independent folding unit. Biochemistry 35, 12723-12732.
12. Han, Z. G., Zhang, Q. H., Ye, M., Kan, L. X., Gu, B. W., et al. (1999) Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulator domain KRNB. J. Biol. Chem. 274, 35741-35748.
13. Huang, X., Yuan, W., Huang, W., Bat Y., Deng, Y., et al. (2006) ZNF569, a novel KRAB-containing zinc fhger protein, suppresses MAPK signaling pathway. Biochem. Biophys. Res. Commun. 346, 621-628.
14. KoM E. N., Ballinger, D. G.;Ding, W., Hunt, S. C., Bowen, B. R., et al. (2000) Evidence of linkage of familial hypoalphalipoproteinemia to a novel locus on chromosome 11q23. Am. J. Hum. Genet. 66, 1845-1856.
15. Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zodv, M. C., et al. (2001) Initial sequencing and analysis of the human genome. Nature 409, 860-921.
16. Lange, R., Christoph, A., Thiesen, H. J., Vopper, G., Johnson, K. R., et al. (1995) Developmentally regulated mouse gene NK 10 encodes a zinc finger repressor with differential DNA binding domains. DNA Cell Biol. 14, 971-981.
17. Langmann, T., Schumacher, S. G., Morham, C., Honer, C., Heimerl, S., et al. (2003) ZNF202 is inversely regulated with its target genes ABCAl and apoE during macrophage differenttiation and foam cell formation. J Lipid Res. 44, 968-977.
18. Lewis, T. S., Shapiro, P. S., and Ahn,. N. G. (1998) Signal transduction through MAP kinase cascades. Adv. Cancer Res. 74, 49-139.
19. Li, Z., Wang, D., Na, X., Schoen, S. R., Messing, E. M., et al. (2003) The VHL protein recruits a novel KRAB-A domain protein to repress HIF-lalpha transcriptional activity. EMBO J. 22, 1857-1867.
20. Liu, H., Zhu, C., Luo, J., Wang, Y., Li D., et al. (2004) ZNF 411, a novel KRAB-containing zinc-finger protein, suppresses MAP kinase signaling pathway. Biochem. Blophys. Res. Commum. 320, 45-53.
21. Lu, D., Searles, M. A., and Klug, A. (2003) Crystal structure of a zinc-finger-RNA complex reveals two modes of molecular recognition. Nature 426, 96-100.
22. Luo, K., Yuan, J., Shan, Y., Li, J., Xu, M., et al. (2006) Activation of transcriptional activities of AP-1 and SRE by a novel zinc finger protein ZNF445. Gene 367, 89-100.
23. Noce, T., Fujiwara, Y., Sezaki, M., Fujimoto, H., and Higashinakagawa, T. (1992) Expression of a mouse zinc finger protein in both spermatocytes and oocytes during meiosis. Dev. Biol. 153, 356-367.
24. Pavletich, N. P. and Pabo, C. 0. (1991) Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science 252, 809-817.
25. Pengue, G., Calabro, V., Cannada-Bartoti, P., Pagliuca, A., and Lania, L.- (1994) Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins. Nucleic Acids Res. 22, 2908-2914.
26. Porsch-Ozcurumez, M., Langmann, T., Heimerl, S., Borsukova, H., Kaminski, W. E., et al. (2001) The zinc finger protein 202 (7NF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gone expression and a modulator of cellular lipid efflux. J Biol. Chem. 276, 12427-12433.
27. Shapiro, M. B. and Senapathy, P. (1987) RNA splice junctions' of different classes of eukaryotes: sequence -statistics and functional implications in gene expression. Nucleic Acids Res. 15, 7155-7174.
28. Shaulian, E. and Karin, M. (2002) AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4, E131-E136.
29. Tara, L. S., Keith, F. S., Jenny, L. M., Paul, S., James, RL S., et al. (2003) The SCAN domain defines a large family of zinc finger transcription factors. Gene 310, 29-38.
30. Treisman, R. (1996) Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8, 205-215.
31. Venter, J. C., Adam, M. D., Myers, E. W., Li P. W., Mural, R. J., et al. (2001) The sequence of the human genome. Science 291, 1304-1351.
32. Wagner, S., Hess, M. A., Ormonde-Hanson, H., Malandro, J., Hu, H., et al. (2000) A broad role for the zinc finger protein ZNF202 in human lipid metabolism. J. Biol. Chem. 275, 15685-15690.
33. Williams, A. J., Khachigian, L. M., and Collins, T. (1995) Isolation and characterization of a novel zinc-finger protein with transcriptional repressor activity. J. Biol. Chem. 270, 22143-22152.
34. Wu, Y., Yu, L., Bi G., Luo, K., Zhou, G., et al. (2003) Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397. Gene 310, 193-201.
35. Yang, H., Yuan, W., Wang, Y., Zhu, C., Liu, B., et al. (2005) ZNF649, a novel Kruppel type zinc finger protein, functions as a transcriptional suppressor. Biochem. Biophys Res Commun. 333, 206-215.
36. Yang, V. W. (1998) Eukaryotic transcription factors: identification, characterization and functions. J. Nutr. 128, 2045-2051.