Dissection of functional domains of the voltage-dependent Ca2+ channel α2δ subunit

Journal of Neuroscience

Volumn 17, Issue 18, 1997, Pages 6884-6891

  Felix, Ricardo ^a   Gurnett, Christina A ^a   De Waard, Michel ^b   Campbell, Kevin P ^a  

^a UNIVERSITY OF IOWA   (United States)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Dihydropyridine binding; L type Ca channel; P Q type Ca channels; Transient expression; tsA201 cells; 2 subunit; subunit

Indexed keywords

CALCIUM CHANNEL; DIHYDROPYRIDINE; PROTEIN SUBUNIT;

ALPHA CHAIN; ARTICLE; CALCIUM TRANSPORT; CHANNEL GATING; HORMONE RELEASE; HUMAN; HUMAN CELL; MEMBRANE BINDING; NEUROTRANSMISSION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; TRANSLATION INITIATION;

EID: 0030882443     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-18-06884.1997     Document Type: Article

References (14)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1995) Current protocols in molecular biology. New York: Wiley.
2. 2δ subunit on ionic and gating current in transiently transfected HEK293 cells. Am J Physiol 270:H1521-H1528.
3. Catterall W (1995) Structure and function of voltage-gated ion channels. Annu Rev Biochem 64:493-531.
4. Chang FC, Hosey MM (1988) Dihydropyridine and phenylalkylamine receptors associated with cardiac and skeletal muscle. J Biol Chem 263:18929-18937.
5. 2+ channels. J Biol Chem 270:30036-30044.
6. Collin T, Wang JJ, Nargeot J, Schwartz A (1993) Molecular cloning of three isoforms of the L-type voltage-dependent calcium channel β subunit from normal human heart. Circ Res 72:1337-1344.
7. 2 and δ are encoded by same gene. J Biol Chem 265:14738-14741.
8. 2+ channel. J Physiol (Lond) 485:619-634.
9. De Waard M, Gurnett CA, Campbell KP (1996) Structural and functional diversity of voltage-activated calcium channels. In: Ion channels, Vol IV (Narahashi T, ed), pp 41-87. New York: Plenum.
10. 2+ channels in mammalian central neurons. Trends Neurosci 18:89-98.
11. Ellinor PT, Zhang JF, Randall AD, Zhou M, Schwarz TL, Tsien RW, Horne WA (1993) Functional expression of a rapidly inactivating neuronal calcium channel. Nature 363:455-458.
12. Grabner M, Wang Z, Hering S, Streissnig J, Glossmann H (1996) Transfer of 1,4-dihydropyridine sensitivity from L-typc to class A (BI) calcium channels. Neuron 16:207-218.
13. 2δ subunit in current stimulation and subunit interaction. Neuron 16:431-440.
14. 1 subunits. J Biol Chem 227:18508-18512.