Defining functional distance using manifold embeddings of gene ontology annotations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 27, 2007, Pages 11334-11339

  Lerman, Gilad ^a,b   Shakhnovich, Boris E ^b  

^a University of Minnesota   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

Diffusion geometry; Domain evolution; Functional annotation; Homology modeling; Kernel methods

Indexed keywords

ARTICLE; CONVERGENT EVOLUTION; GENE MAPPING; GENE ONTOLOGY; GENE SEQUENCE; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC DISTANCE; KERNEL METHOD; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN;

EVOLUTION, MOLECULAR; MODELS, GENETIC; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34547421112     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702965104     Document Type: Article

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