Acute Moderate-Intensity Exercise Induces Vasodilation Through an Increase in Nitric Oxide Bioavailiability in Humans

American Journal of Hypertension

Volumn 20, Issue 8, 2007, Pages 825-830

  Goto, Chikara ^a   Nishioka, Kenji ^a   Umemura, Takashi ^a   Jitsuiki, Daisuke ^a   Sakagutchi, Akihiro ^a   Kawamura, Mitsutoshi ^a   Chayama, Kazuaki ^a   Yoshizumi, Masao ^a   Higashi, Yukihito ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

8 isoprostane; Exercise; forearm blood flow; nitric oxide

Indexed keywords

8 ISOPROSTANE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ADULT; ARTERIAL PRESSURE; ARTICLE; BICYCLE ERGOMETER; BODY MOVEMENT; CONTROLLED STUDY; EXERCISE INTENSITY; FOREARM BLOOD FLOW; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLETHYSMOGRAPHY; PRIORITY JOURNAL; VASCULAR RESISTANCE; VASODILATATION;

ADULT; BIOLOGICAL MARKERS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; DINOPROST; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXERCISE; EXERCISE TEST; EXERCISE TOLERANCE; FOREARM; HEART RATE; HUMANS; MALE; NITRIC OXIDE; NOREPINEPHRINE; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLETHYSMOGRAPHY; REFERENCE VALUES; VASCULAR RESISTANCE; VASODILATION;

EID: 34547411955     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.02.014     Document Type: Article

References (31)

1. Castelli W.P. Epidemiology of coronary heart disease: the Framingham study. Am J Med 76 (1984) 4-12
2. Paffenbarger R.S., Hyde R.T., Wing A.L., Lee I.M., Jung D.L., and Kampert J.B. The association of changes in physical activity level and other lifestyle characteristics with mortality among men. N Engl J Med 328 (1993) 538-545
3. Hornig B.H., Maier V., and Drexler H. Physical training improves endothelial function in patients with chronic heart failure. Circulation 32 (1996) 210-214
4. Hambrecht R., Wolf A., Gielen S., Linke A., Hofer J., Erbs S., Schoene N., and Schuler G. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 342 (2000) 454-460
5. Higashi Y., Sasaki S., Yoshimizu A., Yoshimizu A., Ssaki N., Matsuura H., Kajiyama G., and Oshima T. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide. Circulation 100 (1999) 1194-1202
6. Goto C., Higashi Y., Kimura M., Noma K., Hara K., Nakagawa K., Kawamura M., Chayama K., Yoshizumi M., and Nara I. The effect of different intensities of aerobic exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress. Circulation 108 (2003) 530-535
7. Perticone F., Ceravolo R., Pujia A., Ventura G., Iacopino S., Scozzafava A., Ferraro A., Chello M., Mastroroberto P., Verdecchia P., and Schillaci G. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 104 (2001) 191-196
8. Suwaidi J.A., Hamasaki S., Higano S.T., Nishimura R.A., Holmes Jr. D.R., and Lerman A. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 101 (2001) 948-954
9. Schachinger V., Britten M.B., and Zeiher A.M. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101 (2000) 1899-1906
10. Matsumoto A., Hirata Y., Momomura S., Fujita H., Yao A., Sata M., and Serizawa T. Increased nitric oxide production during exercise. Lancet 343 (1994) 849-850
11. Higashi Y., Sasaki S., Nakagawa K., Matsuura H., Oshima T., and Chayama K. Endothelial function and oxidative stress in renovascular hypertension. N Engl J Med 346 (2002) 1954-1962
12. Eckert S., and Horstkotte D. Comparison of Portapres non-invasive blood pressure measurement in the finger with intra-aortic pressure measurement during incremental bicycle exercise. Blood Press Monit 7 (2002) 179-183
13. Blair S.N., Kohl III H.W., Barlow C.E., Paffenbarger Jr. R.S., Gibbons L.W., and Macera C.A. Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men. JAMA 273 (1995) 1093-1098
14. Chobanian A.V., Bakris G.L., Black H.R., Cushman W.C., Green L.A., Izzo Jr. J.L., Jones D.W., Materson B.J., Oparil S., Wright Jr. J.T., Roccella E.J., National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, and National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 289 (2003) 2560-2572
15. World Health Organization, and International Society of Hypertension Writing Group. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 21 (2003) 1983-1992
16. Abraham P., Saumet J.L., and Chevalier J.M. External iliac artery endofibrosis in athletes. Sports Med 24 (1997) 221-226
17. Bergholm R., Makimattila S., Valkonen M., Liu M.L., Lahdenpera S., Taskinen M.R., Sovijarvi A., Malmberg P., and Yki-Jarvinen H. Intense physical training decreases circulating antioxidants and endothelium-dependent vasodilation in vivo. Atherosclerosis 145 (1999) 341-349
18. Miller V.M., and Vanhoutte P.M. Enhanced release of endothelium-derived factors by chronic increases in blood flow. Am J Physiol 255 (1988) H446-H451
19. Uematsu M., Ohara Y., Navas J.P., Nishida K., Murphy T.J., Alexander R.W., Nerem R.M., and Harrison D.G. Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress. Am J Physiol 269 (1995) C1371-C1378
20. Traub O., and Berk B.C. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 18 (1998) 677-685
21. Davis M.E., Cai H., Drummond G.R., and Harrison D.G. Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ Res 89 (2001) 1073-1080
22. Lovlin R., Cottle W., Pyke I., Kavanagh M., and Belcastro A.N. Are indices of free radical damage related to exercise intensity?. Eur J Appl Physiol 56 (1987) 313-316
23. Davies K.J.A., Quintanilha A.T., Brooks G.A., and Packer L. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 107 (1982) 1198-1205
24. Ohno H. Effects of brief physical exercise on the concentrations of immunereactive superoxide dismutase in human plasma. Tohoku J Exp Med 167 (1992) 301-303
25. Ji L.L. Exercise-induced modulation of antioxidant defense. Ann NY Acad Sci 959 (2002) 82-92
26. Ji L.L., Gomez-Cabrera M.C., Steinhafel N., and Vina A.J. Acute exercise activates nuclear factor-kappaB signaling pathway in rat skeletal muscle. FASEB J 18 (2004) 1499-1506
27. Franzoni F., Ghiadoni L., Galetta F., Plantinga Y., Lubrano V., Huang Y., Salvetti G., Regoli F., Taddei S., Santoro G., and Salvetti A. Physical activity, plasma antioxidant capacity, and endothelial-dependent vasodilation in young and older men. Am J Hypertens 18 (2005) 510-516
28. Saito M., Tsukanaka A., Yanagihara D., and Mano T. Muscle sympathetic nerve responses to graded leg cycling. J Appl Physiol 75 (1993) 663-667
29. Node K., Kitakaze M., Sato H., Koretsune Y., Katsube Y., Karita M., Kosaka H., and Hori M. Effect of acute dynamic exercise on circulating plasma nitric oxide level and correlation to norepinephrine release in normal subjects. Am J Cardiol 79 (1997) 526-528
30. Dinenno F.A., and Joyner M.J. Alpha-adrenergic control of skeletal muscle circulation at rest and during exercise in aging humans. Microcirculation 13 (2006) 329-341
31. Tesfamariam B., Weisbrod R.M., and Cohen R.A. Endothelium inhibits responses of rabbit carotid artery to adrenergic nerve stimulation. Am J Physiol 253 (1987) H792-H798