Mycobacterial heat shock protein-induced blood T lymphocytes subsets and cytokine pattern: Comparison of sarcoidosis with tuberculosis and healthy controls

Respirology

Volumn 12, Issue 3, 2007, Pages 346-354

  Dubaniewicz, Anna ^a   Trzonkowski, Piotr ^a   Dubaniewicz Wybieralska, Mirosława ^a   Dubaniewicz, Andrzej ^b   Singh, Mahavir ^c   Myśliwski, Andrzej ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b Ceynowy's Hospital Poland   (Poland)

^c LIONEX DIAGNOSTICS AND THERAPEUTICS GMBH   (Germany)

Author keywords

Lymphocytes T subset; Peripheral blood mononuclear cell; Sarcoidosis; Th1 Th2 cytokines; Tuberculosis

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL PROTEIN;

ADULT; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG TUBERCULOSIS; MALE; MYCOBACTERIUM; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SARCOIDOSIS; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; CASE CONTROL STUDY; CD4+ T LYMPHOCYTE; CELL CULTURE; COMPARATIVE STUDY; METABOLISM; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PATHOLOGY;

ADULT; BACTERIAL PROTEINS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; FEMALE; HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-6; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; SARCOIDOSIS, PULMONARY; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34547406740     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2007.01076.x     Document Type: Article

References (40)

1. American Thoracic Society. Statement on sarcoidosis. Am. J. Respir. Crit. Care Med. 1999 160 : 736 55.
2. Lillebaek T, Thomsen VO. A patient with suspected sarcoidosis died from miliary tuberculosis. Scand. J. Infect. Dis. 2000 32 : 218 20.
3. Mangiapan G, Hance AJ. Mycobacteria and sarcoidosis: an overview and summary of recent molecular biological data. Sarcoidosis 1995 12 : 20 7.
4. Dubaniewicz A, Kämpfer S, Singh M. Serum anti-mycobacterial heat shock proteins antibodies in sarcoidosis and tuberculosis. Tuberculosis (Edinb.) 2006 86 : 60 7.
5. Dubaniewicz A, Dubaniewicz-Wybieralska M, Sternau A, Zwolska Z, Iżycka-Świeszewska E, et al. Mycobacterium tuberculosis complex and mycobacterial heat shock proteins in lymph nodes from patients with pulmonary sarcoidosis. J. Clin. Microbiol. 2006 44 : 3448 51.
6. Zügel U, Kaufmann SHE. Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin. Microbiol. Rev. 1999 12 : 19 39.
7. Dubaniewicz A, Trzonkowski P, Dubaniewicz-Wybieralska M, Dubaniewicz A, Singh M, et al. Comparative analysis of mycobacterial heat shock proteins-induced apoptosis of peripheral blood mononuclear cells in sarcoidosis and tuberculosis. J. Clin. Immunol. 2006 26 : 243 50.
8. Wendling U, Paul L, van der Zee R, Prakken B, Singh M, et al. A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue. J. Immunol. 2000 164 : 2711 17.
9. Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, et al. A CD4+ T-cell subset inhibits antigen-specific T cell responses and prevents colitis. Nature 1997 389 : 737 42.
10. Trinchieri G. Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection. J. Exp. Med. 2001 194 : F53 7.
11. Valentonyte R, Hampe J, Huse K, Rosenthal P, Albrecht M, et al. Sarcoidosis is associated with a truncating splice site mutation in BTNL2. Nat. Genet. 2005 37 : 357 64.
12. Grunewald J, Olerup O, Persson U, Ohrn MB, Wigzell H, et al. T-cell receptor variable region gene usage by CD4+ and CD8+ T cells in bronchoalveolar lavage fluid and peripheral blood of sarcoidosis patients. Proc. Natl Acad. Sci. USA 1994 91 : 4965 9.
13. Lundqvist C, Baranov V, Teglund S, Hammarstrom S, Hammarstrom ML. Cytokine profile and ultrastructure of intraepithelial gamma delta T cells in chronically inflamed human gingiva suggest a cytotoxic effector function. J. Immunol. 1994 153 : 2302 12.
14. Jiang H, Chess L. Regulation of immune responses by T cells. N. Engl. J. Med. 2006 354 : 1166 76.
15. Inui N, Chida K, Suda T, Nakamura H. TH1/TH2 and TC1/TC2 profiles in peripheral blood and bronchoalveolar lavage fluid cells in pulmonary sarcoidosis. J. Allergy Clin. Immunol. 2001 107 : 337 44.
16. Wahlström J, Katchar K, Wigzell H, Olerup O, Eklund A, et al. Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis. Am. J. Respir. Crit. Care Med. 2001 163 : 115 21.
17. Möllers M, Aries SP, Drömann D, Mascher B, Braun J, et al. Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis. Thorax 2001 56 : 487 93.
18. Bansal AS, Bruce J, Hogan PG, Prichard P, Powell EE. An assessment of peripheral immunity in patients with sarcoidosis using measurements of serum vitamin D3, cytokines and soluble CD23. Clin. Exp. Immunol. 1997 110 : 92 7.
19. Balaji KN, Boom WH. Processing of Mycobacterium tuberculosis bacilli by human monocytes for CD4+αβ and γδ T cells: role of particulate antigen. Infect. Immun. 1998 66 : 98 106.
20. Surcel HM, Troye-Blomberg M, Paulie S, Andersson G, Moreno C, et al. Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens. Immunology 1994 81 : 171 6.
21. Ordway DJ, Costa L, Martins M, Andersson G, Moreno C, et al. Increased interleukin-4 production by CD8 and gammadelta T cells in health-care workers is associated with the subsequent development of active tuberculosis. J. Infect. Dis. 2004 190 : 756 66.
22. Demissie A, Abebe M, Aseffa A, Rook G, Fletcher H, et al. Healthy individuals that control a latent infection with M. tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4delta2. J. Immunol. 2004 172 : 6938 43.
23. van Krevel R, Karyadi E, Preyers F, Leenders M, Kullberg BJ, et al. Increased production of interleukin 4 by CD4 and CD8 T cells from patients with tuberculosis is related to the presence of pulmonary cavities. J. Infect. Dis. 2000 181 : 1194 7.
24. Guerkov RE, Targoni OS, Kreher CR, Tary-Lehmann M, Lehmann PV, et al. Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine. J. Immunol. Methods 2003 279 : 111 21.
25. Alavi MR, Affronti LF. Induction of mycobacterial proteins during phagocytosis and heat shock: a time interval analysis. J. Leukoc. Biol. 1994 55 : 633 41.
26. Javid B, MacAry PA, Oehlmann W, Singh M, Lehner PJ. Peptides complexed with the protein HSP70 generate efficient human cytolytic T-lymphocyte responses. Biochem. Soc. Trans. 2004 32 : 622 5.
27. Hunninghake GW, Crystal RG. Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. N. Engl. J. Med. 1981 305 : 429 34.
28. Nowakowski M, Chan SP, Steiner P, Chice S, Durkin HG. Different distributions of lung and blood lymphocyte subsets in pediatric AIDS or tuberculosis. Ann. Clin. Lab. Sci. 1992 22 : 377 84.
29. Bose MA, Gupta JN, Banavalikar K. Dysregulation of homeostasis of blood lymphocyte subpopulations persists in chronic multibacillary pulmonary tuberculosis patients refractory to treatment. Tuberc. Lung Dis. 1995 76 : 59 64.
30. Müller-Quernheim J, Saltini C, Sondermeyer P, Crystal RG. Compartmentalized activation of the interleukin 2 gene by lung T lymphocytes in active pulmonary sarcoidosis. J. Immunol. 1986 137 : 3475 83.
31. Takahashi S, Setoguchi Y, Nukiwa T, Crystal RG. Soluble interleukin-2 receptor in sera of patients with pulmonary tuberculosis. Chest 1991 99 : 310 14.
32. Lawrence EC, Berger MB, Brousseau KP, Rodriguez TM, Siegel SJ, et al. Elevated serum levels of soluble interleukin-2 receptors in active pulmonary sarcoidosis: relative specificity and association with hypercalcemia. Sarcoidosis 1987 4 : 87 93.
33. Detanico T, Rodrigues L, Sabritto AC, Keisermann M, Bauer ME, et al. Mycobacterial heat shock protein 70 induces interleukin-10 production: immunomodulation of synovial cell cytokine profile and dendritic cell maturation. Clin. Exp. Immunol. 2004 135 : 336 42.
34. Friedland JS, Shattock R, Remick DG, Griffin GE. Mycobacterial 65-kD heat shock protein induces release of proinflammatory cytokines from human monocytic cells. Clin. Exp. Immunol. 1993 91 : 58 62.
35. Rojas RE, Balaji KN, Subramanian A, Boom WH. Regulation of human CD4+αβ T-cell-receptor-positive (TCR+) and γδ TCR+T-cell responses to Mycobacterium tuberculosis by interleukin-10 and transforming growth factor β. Infect. Immun. 1999 67 : 6461 72.
36. Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, et al. The immune paradox of sarcoidosis and regulatory T cells. J. Exp. Med. 2006 203 : 359 70.
37. Planck A, Katchar K, Eklund A, Gripenback S, Grunewald J. T-lymphocyte activity in HLA-DR17 positive patients with active and clinically recovered sarcoidosis. Sarcoidosis Vasc. Diffuse Lung. Dis. 2003 20 : 110 17.
38. Trzonkowski P, Mysliwska J, Szmit E, Wieckiewicz J, Lukaszuk K, et al. Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination - an impact of immunosenescence. Vaccine 2003 21 : 3826 36.
39. Balbi B, Valle MT, Oddera S, Giunti D, Manca F, et al. T-lymphocytes with gamma delta+ V delta 2+ antigen receptors are present in increased proportions in a fraction of patients with tuberculosis or with sarcoidosis. Am. Rev. Respir. Dis. 1993 148 : 1685 90.
40. Li B, Rossman MD, Imir T, Oner-Eyuboglu AF, Lee CW, et al. Disease-specific changes in gammadelta T cell repertoire and function in patients with pulmonary tuberculosis. J. Immunol. 1996 157 : 4222 9.