Disease-Specific Changes in γδ T Cell Repertoire and Function in Patients with Pulmonary Tuberculosis

Journal of Immunology

Volumn 157, Issue 9, 1996, Pages 4222-4229

  Li, Baiqing ^a   Rossman, Milton D ^b   Imir, Turgut ^c   Oner Eyuboglu, A Fusun ^b   Lee, Chung Wa ^b   Biancaniello, Renée ^a   Carding, Simon R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c GAZI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; ARTICLE; BERYLLIOSIS; BLOOD; CLINICAL TRIAL; COMPARATIVE STUDY; CYTOLOGY; FEMALE; FLOW CYTOMETRY; GENE REARRANGEMENT; GENETICS; HUMAN; IMMUNOLOGY; LUNG LAVAGE; LUNG TUBERCULOSIS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MULTICENTER STUDY; MYCOBACTERIUM TUBERCULOSIS; PATHOLOGY; SARCOIDOSIS; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; BERYLLIOSIS; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; FLOW CYTOMETRY; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SARCOIDOSIS; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS, PULMONARY;

EID: 0030292704     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Centers for Disease Control and Prevention. 1993. Tuberculosis morbidity - United States. 1992. MMWR Morb. Mortal. Wkly. Rep. 42:696.
2. Snider, D. E., Jr., M. Raviglione, and A. Kochi. 1994. Global burden of tuberculosis. In Tuberculosis: Pathogenesis, Protection, and Control. B. R. Bloom, ed. ASM Press, Washington, DC, p. 3.
3. Mackaness, G. B. 1969. The influence of immunologically committed lymphoid cells on macrophage activity in vivo. J. Exp. Med. 129:973.
4. North, R. J. 1974. T cell dependence of macrophage activation and mobilization during infection with Mycobacterium tuberculosis. Infect. Immun. 10:66.
5. Kauffmann, S. H. E. 1989. In vitro analysis of the cellular mechanisms involved in immunity to tuberculosis. Rev. Infect. Dis. 11:448.
6. Selwyn, P. A., D. Hartel, V. A. Lewis, E. E. Schoenbaum, S. H. Vermund, R. S. Klein, A. T. Walker, and G. H. Friedland. 1989. A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N. Engl. J. Med. 320:545.
7. Hahn, H., and S. H. E. Kauffmann. 1981. The role of cell-mediated immunity in bacteria infections. Rev. Infect. Dis. 3:1221.
8. Rook, G. A., B. R. Champion, J. Steele, A. M. Varey, and J. L. Stanford. 1985. I-A restricted activation by T cell lines of anti-tuberculosis activity in murine macrophages. Clin. Exp Immunol. 59:414.
9. Dannenbery, A. M., Jr. 1991. Delayed-type hypersensitivity and cell-mediated immunity in the pathogenesis of tuberculosis. Immunol. Today 12:228.
10. Augustin, A, R. T. Kubo, and G. K. Sim. 1989. Resident pulmonary lymphocytes expressing the γ/δ T cell receptor. Nature 340:239.
11. + T cells is activated by Mycobacterium tuberculosis but not by its 65-KD heat shock protein. J. Exp. Med. 171:667.
12. + T cells to Mycobacterium tuberculosis is restricted to Vγ9-bearing cells. J. Exp. Med. 173:1331.
13. Haregewoin, A., G. Soman, R. C. Hom, and R. W. Finberg. 1989. Human γδ T cells respond to mycobacterial heat shock protein. Nature 340:309.
14. Munk, M. E., B. Schoel, S. Modrow, R. W. Karr, R. A. Young, and S. H. E. Kauffmann. 1989. T lymphocytes from healthy individuals with specificity to self-epitopes shared by mycobacterial and human 65-kilodalton heat shock protein. J. Immunol. 143:2844.
15. Boom, W. H., K. A. Chervenak, M. A. Mincek, and J. J. Ellner. 1992. Role of the mononuclear phagocyte as an antigen-presenting cell for human γδ T cells activated by live Mycobacterium tuberculosis. Infect. Immun. 60:3480.
16. Lefranc, M.-P., A. Forster, R. Baer, M. A. Stinson, and T. H. Rabbitts. 1986. Diversity and rearrangement of the human T cell rearranging γ genes: nine germline variable genes belonging to two subgroups. Cell 45:237.
17. De Libero, G., G. Casorati, C. Giachino, C. Carbonara, N. Migone, P. Matzinger, and A. Lanzavecchia. 1991. Selection by two powerful antigens may account for the presence of the major population of human peripheral γ/δ T cells. J. Exp. Med. 173:1311.
18. Panchamoorthy, G., J. McLean, R. L. Modlin, C. T. Morita, S. Ishikawa, M. B. Brenner, and H. Band. 1991. A predominance of the T cell receptor Vγ2/Vδ2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition. J. Immunol. 147:3360.
19. Pechhold, K., D. Wesch, S. Schondelmaier, and D. Kabelitz. 1994. Primary activation of Vγ9-expressing γδ T cells by Mycobacterium tuberculosis: requirement for Th1-type CD4 T cell help and inhibition by IL-10. J. Immunol. 152: 4984.
20. Pfeffer, K., B. Schoel, H. Guile, S. H. E. Kaufmann, and H. Wagner. 1990. Primary responses of human T cells to mycobacteria: a frequent set of γ/δT cells are stimulated by protease-resistant ligands. Eur. J. Immunol. 20:1175.
21. Tanaka, Y., S. Sano, E. Nieves, G. De Libero, D. Rosa, R. L. Modlin, M. B. Brenner, B. R. Bloom, and C. T. Morita. 1994. Nonpeptide ligands for human γδ T cells. Proc. Natl. Acad. Sci. USA 91:8175.
22. Schoel, B., S. Sprenger, and S. H. E. Kauffmann. 1994. Phosphate is essential for stimulation of Vγ9 Vδ2 T lymphocytes by mycobacterial low molecular weight ligand. Eur. J. Immunol. 24:1886.
23. Constant, P., F. Davodeau, M. A. Peyrat., Y. Poquet, G. Puzo, M. Bonneville, and J.-J. Fournie. 1994. Stimulation of human γδ T cells by nonpeptidic mycobacterial ligands. Science 264:267.
24. Ito, M., N. Kojiro, T. Ikeda, T. Ito, J. Funada, and T. Kokubu. 1992. Increased proportions of peripheral blood γδ T cells in patients with pulmonary tuberculosis. Chest 102:195.
25. + antigen receptors are present in increased proportions in a fraction of patients with tuberculosis or with sarcoidosis. Am. Rev. Respir. Dis. 148:1685.
26. Tazi, A., I. Fajac, P. Soler, D. Valeyre, J. P. Battesti, and A. J. Hance. 1991. Gamma/delta T-lymphocytes are not increased in number in granulomatous lesions of patients with tuberculosis and sarcoidosis. Am. Rev. Respir. Dis. 144: 1373.
27. Tazi, A., F. Bouchonnet, D. Valeyre, J. Cadranel, J. P. Battesti, and A. J. Hance. 1992. Characterization of γ/δ T-lymphocytes in the peripheral blood of patients with active tuberculosis. Am. Rev. Respir. Dis. 146:1216.
28. Barnes, P. F., C. L. Grisso, J. S. Abrams, H. Band, T. H. Rea, and R. L. Modlin. 1992. γδ T lymphocytes in human tuberculosis. J. Infect. Dis. 165:506.
29. Ueta, C., I. Tsuyuguchi, H. Kawasumi, T. Takashima, H. Toba, and S. Kishimoto. 1994. Increase of γ/δ T cells in hospital workers who are in close contact with tuberculosis patients. Infect. Immun. 62:5434.
30. Rossman, M. D., J. A. Kem, J. A. Elias, M. R. Cullen, P. E. Epstein, O. P. Preuss, T. N. Markham, and R. P. Daniele. 1988. Proliferative response of bronchoalveolar lymphocytes to beryllium: a test for chronic beryllium disease. Ann. Intern. Med. 108:687.
31. Coding, J. W. 1983. Monoclonal Antibodies: Principles and Practice. Academic Press, London, p. 232.
32. Boom, W. H., K. N. Balaji, R. Nayak, K. Tsukaguchi, and K. A. Chervenak. 1994. Characterization of a 10- to 14-kilodalton protease-sensitive Mycobacterium tuberculosis H37Ra antigen that stimulates human γδ T cells. Infect. Immun. 62:5511.
33. Groh, V., S. Porcelli, M. Fabbi, L. L. Lanier, L. J. Picker, T. Anderson, R. A. Warnke, A. K. Bhan, J. L. Strominger, and M. B. Brenner. 1989. Human lymphocytes bearing T-cell receptor γ/δ are phenotypically diverse and evenly distributed throughout the lymphoid system. J. Exp. Med. 169:1277.
34. Schondelmaier, S. D. Wesch, K. Pechhold, and D. Kabelitz. 1993. Vγ gene usage in peripheral blood γδ T cells. Immunol. Lett. 38:121.
35. + T cells in pulmonary sarcoidosis. J. Clin. Invest. 91:292.
36. Nakata, K., T. Sugie, H. Nakano, T. Sakai, and M. Aoki. 1994. Gamma-delta T cells in sarcoidosis: correlation with clinical features. Am. J. Respir. Crit. Care. Med. 149:981.
37. Uyemura, K., R. J. Deans, H. Band, J. Ohmen, G. Panchamoorthy, C. T. Monta, T. H. Rea, and R. L. Modlin. 1991. Evidence for clonal selection of γδ T cells in response to a human pathogen. J. Exp. Med. 174:683.
38. Burk, M. R., L. Mori, and G. De Libero. 1995. Human Vγ9-Vδ2 cells stimulated in a cross-reactive fashion by a variety of phosphorylated metabolites. Eur. J. Immunnol. 25:2052.
39. Ohmen, J. D., P. F. Barnes, K. Uyemura, S. Lu, C. L. Grisso, and R. L. Modlin. 1991. The T cell receptors of human γδ T cells reactive to Mycobacterium tuberculosis are encoded by specific V genes but diverse V-J junctions. J. Immunol. 147:3353.
40. Davodeau, F., M-A. Peyrat, M-M. Hallet, J. Gaschet, I. Houde, R. Vivien, H. Vie, and M. Bonneville. 1993. Close correlation between Daudi and Mycobacterial antigen recognition by human γδ T cells and expression of V9JPC1γ/V2DJCδ-encoded T cell receptors. J. Immunol. 151:1214.
41. Breti, T. M., I. L. M. Wolvers-Tettero, and J. J. M. van Dongen. 1994. Unique selection determinant in polyclonal Vδ2-Jδ1 junctional regions of human peripheral γδ T lymphocytes. J. Immunol. 152:2860.
42. Schild, H., N. Mavaddat, C. Litzenberger, E. W. Ehrich, M. M. Davis, J. A. Bluestone, L. Matis, R. K. Draper, and Y-h. Chien. 1994. The nature of major histocompatibility complex recognition by γδ T cells. Cell 76:29.
43. Kabelitz, D., K. Pechhold, A. Bender, S. Wesselborg, D. Wesch, K. Friese, and O. Janssen. 1991. Activation and activation-driven death of human γ/δ T cells. Immunol. Rev. 120:71.
44. Havlir, D. V., J. J. Ellner, K. A. Chervenak, and W. H. Boom. 1991. Selective expansion of human γδ T cells by monocytes infected with live Mycobacterium tuberculosis. J. Clin. Invest. 87:729.
45. Gercken, J., J. Pryjma, M. Ernst, and H. D. Flad. 1994. Defective antigen presentation by Mycobacterium tuberculosis-infected macrophages. Infec. Immun. 62:3472-3478.
46. Hinz, T., D. Wesch, K. Friese, A. Reckziegel, B. Arden, and D. Kabelitz. 1994. T cell receptor γδ repertoire in HIV-1-infected individuals. Eur. J. Immunol. 24:3044.
47. Britton, W. J., P. W. Roche, and N. Winter. 1994. Mechanisms of persistence of mycobacteria. Trends Microbiol. 2:284.