-
1
-
-
14744297828
-
-
The medicinal chemistry of botulinum, ricin and anthrax toxins
-
R. P. Hicks, M. G. Hartelt, D. A. Nichols, A. K. Bhattacharjee, J. E. van Hamont, and D. R. Skillman, Curr. Med. Chem. The medicinal chemistry of botulinum, ricin and anthrax toxins Vol. 12, 667-90 (2005).
-
(2005)
Curr. Med. Chem
, vol.12
, pp. 667-690
-
-
Hicks, R.P.1
Hartelt, M.G.2
Nichols, D.A.3
Bhattacharjee, A.K.4
van Hamont, J.E.5
Skillman, D.R.6
-
3
-
-
4444317796
-
-
Antitoxins: novel strategies to target agents of bioterrorism
-
G. J. Rainey and J. A. Young, Nat. Rev. Microbiol. Antitoxins: novel strategies to target agents of bioterrorism Vol. 2, 721-6 (2004).
-
(2004)
Nat. Rev. Microbiol
, vol.2
, pp. 721-726
-
-
Rainey, G.J.1
Young, J.A.2
-
4
-
-
33746008486
-
-
Devel. Rational approaches to natural-product-based drug design
-
L. O. Haustedt, C. Mang, K. Siems, and H. Schiewe, Curr. Opin. Drug Discov. Devel. Rational approaches to natural-product-based drug design Vol. 9, 445-62 (2006).
-
(2006)
Curr. Opin. Drug Discov
, vol.9
, pp. 445-462
-
-
Haustedt, L.O.1
Mang, C.2
Siems, K.3
Schiewe, H.4
-
5
-
-
0036589890
-
-
Structure-based approaches to drug design and virtual screening
-
B. Waszkowycz, Curr. Opin. Drug Discov. Devel. Structure-based approaches to drug design and virtual screening Vol. 5, 407-13 (2002).
-
(2002)
Curr. Opin. Drug Discov. Devel
, vol.5
, pp. 407-413
-
-
Waszkowycz, B.1
-
6
-
-
0000577984
-
Chem. Rev. The "One-Bead-One- Compound" Combinatorial Library Method
-
K. S. Lam, M. Lebl, and V. Krchnak, Chem. Rev. The "One-Bead-One- Compound" Combinatorial Library Method Vol. 97, (1997).
-
(1997)
, vol.97
-
-
Lam, K.S.1
Lebl, M.2
Krchnak, V.3
-
7
-
-
0025835310
-
-
T. Clackson, H. R. Hoogenboom, A. D. Griffiths, and G. Winter, Nature Making antibody fragments using phage display libraries Vol. 352, 624-8 (1991).
-
(1991)
Nature Making antibody fragments using phage display libraries
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
9
-
-
33645798851
-
-
B. N. Giepmans, S. R. Adams, M. H. Ellisman, and R. Y. Tsien, Science The fluorescent toolbox for assessing protein location and function Vol. 312, 217-24 (2006).
-
(2006)
Science The fluorescent toolbox for assessing protein location and function
, vol.312
, pp. 217-224
-
-
Giepmans, B.N.1
Adams, S.R.2
Ellisman, M.H.3
Tsien, R.Y.4
-
10
-
-
33845484796
-
-
Intracellular protein interaction mapping with FRET hybrids
-
X. You, A. W. Nguyen, A. Jabaiah, M. A. Sheff, K. S. Thorn, and P. S. Daugherty, Proc. Natl. Acad. Sci. USA Intracellular protein interaction mapping with FRET hybrids Vol. 103, 18458-63 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18458-18463
-
-
You, X.1
Nguyen, A.W.2
Jabaiah, A.3
Sheff, M.A.4
Thorn, K.S.5
Daugherty, P.S.6
-
11
-
-
34547293080
-
-
A Cell-based Approach for Biosynthesis/Screening of Cyclic Peptide Libraries against Bacterial Toxins
-
J. A. Camarero, R. Kimura, and A. T. Tran, J. Pept. Sci. A Cell-based Approach for Biosynthesis/Screening of Cyclic Peptide Libraries against Bacterial Toxins Vol. 12, 89 (2006).
-
(2006)
J. Pept. Sci
, vol.12
, pp. 89
-
-
Camarero, J.A.1
Kimura, R.2
Tran, A.T.3
-
12
-
-
0000947082
-
-
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
-
S. H. Leppla, Proc. Natl. Acad. Sci. USA Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells Vol. 79, 3162-6 (1982).
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 3162-3166
-
-
Leppla, S.H.1
-
13
-
-
0028088404
-
-
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
-
K. R. Klimpel, N. Arora, and S. H. Leppla, Mol. Microbiol. Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity Vol. 13, 1093-100 (1994).
-
(1994)
Mol. Microbiol
, vol.13
, pp. 1093-1100
-
-
Klimpel, K.R.1
Arora, N.2
Leppla, S.H.3
-
14
-
-
3242804491
-
-
Stop the killer: how to inhibit the anthrax lethal factor metalloprotease
-
C. Montecucco, F. Tonello, and G. Zanotti, Trends Biochem. Sci. Stop the killer: how to inhibit the anthrax lethal factor metalloprotease Vol. 29, 282-5 (2004).
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 282-285
-
-
Montecucco, C.1
Tonello, F.2
Zanotti, G.3
-
15
-
-
0035829509
-
-
K. A. Bradley, J. Mogridge, M. Mourez, R. J. Collier, and J. A. Young, Nature Identification of the cellular receptor for anthrax toxin Vol. 414, 225-9 (2001).
-
(2001)
Nature Identification of the cellular receptor for anthrax toxin
, vol.414
, pp. 225-229
-
-
Bradley, K.A.1
Mogridge, J.2
Mourez, M.3
Collier, R.J.4
Young, J.A.5
-
16
-
-
0038303163
-
-
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor
-
H. M. Scobie, G. J. Rainey, K. A. Bradley, and J. A. Young, Proc. Natl. Acad. Sci. USA Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor Vol. 100, 5170-4 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5170-5174
-
-
Scobie, H.M.1
Rainey, G.J.2
Bradley, K.A.3
Young, J.A.4
-
17
-
-
3542993051
-
-
E. Santelli, L. A. Bankston, S. H. Leppla, and R. C. Liddington, Nature Crystal structure of a complex between anthrax toxin ana its host cell receptor Vol. 430, 905-8 (2004).
-
(2004)
Nature Crystal structure of a complex between anthrax toxin ana its host cell receptor
, vol.430
, pp. 905-908
-
-
Santelli, E.1
Bankston, L.A.2
Leppla, S.H.3
Liddington, R.C.4
-
18
-
-
0028872463
-
infect. Immun
-
V. M. Gordon, K. R. Klimpel, N. Arora, M. A. Henderson, and S. H. Leppla, infect. Immun. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases Vol. 63, 82-7 (1995).
-
(1995)
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
, vol.63
, pp. 82-87
-
-
Gordon, V.M.1
Klimpel, K.R.2
Arora, N.3
Henderson, M.A.4
Leppla, S.H.5
-
19
-
-
0028018856
-
-
Anthrax protective antigen forms oligomers during intoxication of mammalian cells
-
J. C. Milne, D. Furlong, P. C. Hanna, J. S. Wall, and R. J. Collier, J. Biol. Chem. Anthrax protective antigen forms oligomers during intoxication of mammalian cells Vol. 269, 20607-12 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 20607-20612
-
-
Milne, J.C.1
Furlong, D.2
Hanna, P.C.3
Wall, J.S.4
Collier, R.J.5
-
20
-
-
0037144590
-
-
J. M. Park, F. R. Greten, Z. W. Li, and M. Karin, Science Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition Vol. 297, 2048-51 (2002).
-
(2002)
Science Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
, vol.297
, pp. 2048-2051
-
-
Park, J.M.1
Greten, F.R.2
Li, Z.W.3
Karin, M.4
-
21
-
-
0346251030
-
-
J. E. Kirby, Infect. Immun. Anthrax lethal toxin induces human endothelial cell apoptosis 72, 430-9 (2004).
-
J. E. Kirby, Infect. Immun. Anthrax lethal toxin induces human endothelial cell apoptosis Vol. 72, 430-9 (2004).
-
-
-
-
22
-
-
0042964832
-
-
A. Agrawal, J. Lingappa, S. H. Leppla, S. Agrawal, A. Jabbar, C. Quinn, and B. Pulendran, Nature Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin Vol. 424, 329-34 (2003).
-
(2003)
Nature Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin
, vol.424
, pp. 329-334
-
-
Agrawal, A.1
Lingappa, J.2
Leppla, S.H.3
Agrawal, S.4
Jabbar, A.5
Quinn, C.6
Pulendran, B.7
-
23
-
-
32044445840
-
-
R. H. Kimura, A. T. Tran, and J. A. Camarero, Angew. Chem. Int. Ed. Biosynthesis of the cyclotide kalata Bl by using protein splicing 45, 973-6 (2006).
-
R. H. Kimura, A. T. Tran, and J. A. Camarero, Angew. Chem. Int. Ed. Biosynthesis of the cyclotide kalata Bl by using protein splicing Vol. 45, 973-6 (2006).
-
-
-
-
24
-
-
0033579483
-
-
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif
-
D. J. Craik, N. L. Daly, T. Bond, and C. Waine, J. Mol. Biol. Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif Vol. 294, 1327-36 (1999).
-
(1999)
J. Mol. Biol
, vol.294
, pp. 1327-1336
-
-
Craik, D.J.1
Daly, N.L.2
Bond, T.3
Waine, C.4
-
25
-
-
0037424506
-
-
K. J. Rosengren, N. L. Daly, M. R. Plan, C. Waine, and D. J. Craik, J. Biol. Chem. Twists, knots, and rings in proteins. Structural definition of the cyclotide framework 278, 8606-16 (2003).
-
K. J. Rosengren, N. L. Daly, M. R. Plan, C. Waine, and D. J. Craik, J. Biol. Chem. Twists, knots, and rings in proteins. Structural definition of the cyclotide framework Vol. 278, 8606-16 (2003).
-
-
-
-
26
-
-
2442715239
-
-
Thermal, chemical, and enzymatic stability of the cyclotide kalata Bl, the importance of the cyclic cystine knot
-
M. L. Colgrave and D. J. Craik, Biochemistry Thermal, chemical, and enzymatic stability of the cyclotide kalata Bl : the importance of the cyclic cystine knot Vol. 43, 5965-75 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 5965-5975
-
-
Colgrave, M.L.1
Craik, D.J.2
-
27
-
-
4444359659
-
-
Novel strategies for isolation and characterization of cyclotides: the discovery of bioactive macrocyclic plant polypeptides in the Violaceae
-
U. Goransson, E. Svangard, P. Claeson, and L. Bohlin, Curr. Protein Pept. Sci. Novel strategies for isolation and characterization of cyclotides: the discovery of bioactive macrocyclic plant polypeptides in the Violaceae Vol. 5, 317-29 (2004).
-
(2004)
Curr. Protein Pept. Sci
, vol.5
, pp. 317-329
-
-
Goransson, U.1
Svangard, E.2
Claeson, P.3
Bohlin, L.4
-
28
-
-
4043144831
-
-
D. J. Craik, N. L. Daly, J. Mulvenna, M. R. Plan, and M. Trabi, Curr. Protein Pept. Sci. Discovery, structure and biological activities of the cyclotides 5, 297-315 (2004).
-
D. J. Craik, N. L. Daly, J. Mulvenna, M. R. Plan, and M. Trabi, Curr. Protein Pept. Sci. Discovery, structure and biological activities of the cyclotides Vol. 5, 297-315 (2004).
-
-
-
-
29
-
-
33646248365
-
-
D. J. Craik, M. Cemazar, C. K. Wang, and N. L. Daly, Biopolymers The cyclotide family of circular miniproteins: nature's combinatorial peptide template Vol. 84, 250-66 (2006).
-
(2006)
Biopolymers The cyclotide family of circular miniproteins: Nature's combinatorial peptide template
, vol.84
, pp. 250-266
-
-
Craik, D.J.1
Cemazar, M.2
Wang, C.K.3
Daly, N.L.4
-
30
-
-
33645028340
-
-
The cyclotides and related macrocyclic peptides as scaffolds in drug design
-
D. J. Craik, M. Cemazar, and N. L. Daly, Curr. Opin. Drug Discov. Devel. The cyclotides and related macrocyclic peptides as scaffolds in drug design Vol. 9, 251-60 (2006).
-
(2006)
Curr. Opin. Drug Discov. Devel
, vol.9
, pp. 251-260
-
-
Craik, D.J.1
Cemazar, M.2
Daly, N.L.3
-
31
-
-
0033791223
-
-
P. E. Dawson and S. B. Kent, Annu. Rev. Biochem. Synthesis of native proteins by chemical ligation 69, 923-60 (2000).
-
P. E. Dawson and S. B. Kent, Annu. Rev. Biochem. Synthesis of native proteins by chemical ligation Vol. 69, 923-60 (2000).
-
-
-
-
33
-
-
0033575092
-
-
Biosynthesis of a Head-to-Tail Cyclized Protein with Improved Biological Activity
-
J. A. Camarero and T. W. Muir, J. Am. Chem. Soc. Biosynthesis of a Head-to-Tail Cyclized Protein with Improved Biological Activity Vol. 121, 5597-5598 (1999).
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 5597-5598
-
-
Camarero, J.A.1
Muir, T.W.2
-
34
-
-
0037548053
-
-
Semisynthesis of proteins by expressed protein ligation
-
T. W. Muir, Annu. Rev. Brochem. Semisynthesis of proteins by expressed protein ligation Vol. 72, 249-289 (2003).
-
(2003)
Annu. Rev. Brochem
, vol.72
, pp. 249-289
-
-
Muir, T.W.1
-
35
-
-
0034828385
-
-
Peptide chemical ligation Inside living cells: vivo generation of a circular protein domain
-
J. A. Camarero, D. Fushman, D. Cowburn, and T W. Muir, Bioorg, Med. Chem. Peptide chemical ligation Inside living cells: in vivo generation of a circular protein domain Vol. 9, 2479-84, (2001).
-
(2001)
Bioorg, Med. Chem
, vol.9
, pp. 2479-2484
-
-
Camarero, J.A.1
Fushman, D.2
Cowburn, D.3
Muir, T.W.4
-
38
-
-
21444436724
-
-
A. W. Nguyen and P S. Dougherty, Nat. Biotechnol. Evolutionary optimization of fluorescent proteins for intracellular FRET 23, 355-60 (2005).
-
A. W. Nguyen and P S. Dougherty, Nat. Biotechnol. Evolutionary optimization of fluorescent proteins for intracellular FRET Vol. 23, 355-60 (2005).
-
-
-
-
39
-
-
0347192782
-
-
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor
-
B. E. Turk, T. Y. Wong, R. Schwarzenbacher, E. T. Jarrell, S. H. Leppla, R. J. Collier, R. C. Liddington, and L. C. Cantley, Nat. Struct. Mol. Biol. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor Vol. 11, 60-6 (2004).
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 60-66
-
-
Turk, B.E.1
Wong, T.Y.2
Schwarzenbacher, R.3
Jarrell, E.T.4
Leppla, S.H.5
Collier, R.J.6
Liddington, R.C.7
Cantley, L.C.8
-
40
-
-
33750728028
-
-
T. H. Evers, E. M. van Dongen, A. C. Faesen, E. W. Meijer, and M. Merkx, Biochemistry Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers Vol. 45, 13183-92 (2006).
-
(2006)
Biochemistry Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers
, vol.45
, pp. 13183-13192
-
-
Evers, T.H.1
van Dongen, E.M.2
Faesen, A.C.3
Meijer, E.W.4
Merkx, M.5
-
41
-
-
0020452974
-
-
Origin of replication of Escherichia coli plasmid RSF 1030
-
T Som and J. Tomizawa, Mol. Gen. Genet. Origin of replication of Escherichia coli plasmid RSF 1030 Vol. 187, 375-83 (1982).
-
(1982)
Mol. Gen. Genet
, vol.187
, pp. 375-383
-
-
Som, T.1
Tomizawa, J.2
-
42
-
-
31744435251
-
-
Mapping structural interactions using in-cell NMR spectroscopy STINTNMR
-
D. S. Burz, K. Dutta, D. Cowburn, and A. Shekhtman, Nat. Methods Mapping structural interactions using in-cell NMR spectroscopy (STINTNMR)Vol. 3, 91-3 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 91-93
-
-
Burz, D.S.1
Dutta, K.2
Cowburn, D.3
Shekhtman, A.4
-
43
-
-
27744517176
-
-
Expressed protein ligation: a new tool for the biosynthesis of cyclic polypeptides
-
R. Kimura and J. A. Camarero, Protein Pept. Lett. Expressed protein ligation: a new tool for the biosynthesis of cyclic polypeptides Vol. 12, 789-94 (2005).
-
(2005)
Protein Pept. Lett
, vol.12
, pp. 789-794
-
-
Kimura, R.1
Camarero, J.A.2
-
44
-
-
0036489968
-
-
The cyclotides: novel macrocyclic peptides as scaffolds in drug design
-
D. J. Craik, S. Simonsen, and N. L. Daly, Curr. Opin. Drug Discov. Devel. The cyclotides: novel macrocyclic peptides as scaffolds in drug design Vol. 5, 251-260 (2002).
-
(2002)
Curr. Opin. Drug Discov. Devel
, vol.5
, pp. 251-260
-
-
Craik, D.J.1
Simonsen, S.2
Daly, N.L.3
-
45
-
-
34548127744
-
-
Cells, DOI 10.1002/cbic.200700183
-
J. A. Camarero, R. H. Kimura, Y.-H. Woo, A. Shekhtman and J. Cantor, CriemBioChem Biosynthesis of a Fully Functional Cyclotide inside Living Bacterial Cells, DOI 10.1002/cbic.200700183
-
CriemBioChem Biosynthesis of a Fully Functional Cyclotide inside Living Bacterial
-
-
Camarero, J.A.1
Kimura, R.H.2
Woo, Y.-H.3
Shekhtman, A.4
Cantor, J.5
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