5-Androstenediol promotes survival of γ-irradiated human hematopoietic progenitors through induction of nuclear factor-κB activation and granulocyte colony-stimulating factor expression

Molecular Pharmacology

Volumn 72, Issue 2, 2007, Pages 370-379

  Xiao, Mang ^a,b   Inal, Cynthia E ^a   Parekh, Vaishali I ^a   Chang, Cheng Min ^a   Whitnall, Mark H ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b ARMED FORCES RADIOBIOLOGY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIOL; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PROTEIN P53; SMALL INTERFERING RNA;

ARTICLE; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; CYTOKINE RELEASE; DNA BINDING; GAMMA IRRADIATION; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIATION INJURY; RADIOSENSITIVITY; WESTERN BLOTTING;

ANDROSTENEDIOL; ANTIGENS, CD34; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; DNA-ACTIVATED PROTEIN KINASE; GAMMA RAYS; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-6; NF-KAPPA B; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34547198470     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.035394     Document Type: Article

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