Oxidative damage in rat erythrocyte membranes following ethanol intake: Effect of ethyl pyruvate

Chemico-Biological Interactions

Volumn 169, Issue 2, 2007, Pages 122-131

  Gabbianelli, Rosita ^a   Cifani, Carlo ^a   Massi, Maurizio ^a   Polidori, Carlo ^a   Falcioni, Giancarlo ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Alcohol; Erythrocyte; Ethyl pyruvate; Fluidity; Oxidative stress; Rats

Indexed keywords

ALCOHOL; FREE RADICAL;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANISOTROPY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE MEMBRANE; LIPID OXIDATION; LIPID PEROXIDATION; MALE; MEMBRANE FLUIDITY; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; CATALASE; ERYTHROCYTE MEMBRANE; ETHANOL; GLUTATHIONE PEROXIDASE; MALE; OXIDATIVE STRESS; PYRUVATES; RATS; SUPEROXIDE DISMUTASE;

ANIMALIA; RATTUS;

EID: 34547160449     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.06.001     Document Type: Article

References (49)

1. Cederbaum A. Introduction-serial review: alcohol, oxidative stress and cell injury. Free Radic. Biol. Med. 31 (2001) 1524-1526
2. Nordmann R., Ribiere C., and Rouach H. Implication of free radical mechanisms in ethanol induced cellular injury. Free Radic. Biol. Med. 12 (1992) 219-240
3. Little H.J. The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanol. Pharmacol. Ther. 84 (1999) 333-353
4. Kim B.J., Hood B.L., Aragon R.A., Hardwick J.P., Conrads T.P., Veenstra T.D., and Song B.J. Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells. Proteomics 6 (2006) 1250-1260
5. Halliwell B., and Gutteridge J.M.C. Oxygen is poisonous-an introduction to oxygen toxicity and free radicals. Free Radical in Biology and Medicine (1989), Oxford University Press Inc., New York pp. 1-20
6. Song B.L., Koop D.R., Ingelman-Sundberg M., Nanji A., and Cederbaum A.I. Alcohol Clin. Exp. Res. 20 (1996) 138A-146A
7. Miles M.F., Wilke N., Elliot M., Tanner W., and Shah S. Ethanol-responsive genes in neural cells include the 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) molecular chaperones. Mol. Pharmacol. 46 (1994) 873-879
8. +-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury. J. Biol. Chem. 278 (2003) 51360-51371
9. Bailey S.M., and Cubbingham C.C. Contribution of mitochondria to oxidative stress associated with alcoholic liver disease. Free Radic. Biol. Med. 32 (2002) 11-16
10. Kono H., Rusyn I., Yin M., Gabele E., Yamashina S., Dikalova A., Kadiiska M.B., Connor H.D., Mason R.P., Segal B.H., Bradford B.U., Holland S.M., and Thurman R.G. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J. Clin. Invest. 106 (2000) 867-872
11. Moller P., and Wallin H. Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product. Mutat. Res. 410 (1998) 271-279
12. Vaca C.E., Wilhelm J., and Harms-Ringdahl M. Interaction of lipid peroxidation products with DNA: a review. Mutat. Res. 195 (1988) 137-149
13. O'Donnell-Tormey J., Nathan C.F., Lanks K., DeBoer C.J., and Harpe J. Secretion of pyruvate: an antioxidant defence of mammalian cells. J. Exp. Med. 165 (1987) 500-514
14. Varma S.D., Devamanoharan P.S., and Ali A.H. Prevention of intracellular oxidative stress to lens by pyruvate and its ester. Free Radic. Biol. Med. 28 (1998) 131-135
15. Olek R.A., Antosiewicz J., Popinigis J., Gabbianelli R., Fedeli D., and Falcioni G. Pyruvate but not lactate prevents NADH-induced myoglobin oxidation. Free Radic. Biol. Med. 38 (2005) 1484-1490
16. Constantopoulos G., and Barranger G.A. Nonenzymatic decarboxylation of pyruvate. Anal. Biochem. 139 (1984) 353-358
17. De Boer L.W., Bekx P.A., Han L., and Steinke L. Pyruvate enhances recovery of rat hearts after ischemia and reperfusion by preventing free radical generation. Am. J. Physiol. Heart Circul. Physiol. 265 (1993) 1571-1576
18. Sims C.A., Wattanasirichaigoon S., Menconi M.J., Ajami A.M., and Fink M.P. Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats. Crit. Care Med. 29 (2001) 1513-1518
19. Bramley T.A., Coleman L., and Finean J.B. Chemical, enzymological and permeability properties of human erythrocyte ghosts prepared by hypotonic lysis in media of different osmolarities. Biochim. Biophys. Acta 241 (1971) 752-769
20. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.L. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
21. Folch J., Less M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226 (1957) 466-468
22. Konings A.W.T. Lipid peroxidation in liposomes. In: Gregoriadis G. (Ed). Liposomes Technology (1984), CRC Press, Inc., Boca Raton, FL 139-161
23. Antonini E., and Brunori M. Hemoglobin and Myoglobin in their Reactions with Ligands (1971), North-Holland Publishing Company, Amsterdam, London pp. 10-11
24. Paglia D.E., and Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 276 (1967) 368-374
25. Luck H. Catalase. In: Bergmayer M.V. (Ed). Method of Enzymatic Analysis (1974), Accademic Press, Verlag Chemic, New York 885-887
26. Misra H.P., and Fridovich I. The generation of superoxide radical during the autoxidation of hemoglobin. J. Biol. Chem. 247 (1972) 6960-6962
27. Concetti A., Massei P., Rotilio G., Brunori M., and Rachmilewitz E.A. Superoxide dismutase in red blood cells: method of assay and enzyme content in normal subjects and in patients with beta-thalassemia (major and intermedia). J. Lab. Clin. Med. 87 (1976) 1057-1064
28. Shinitzky M., and Barenholz Y. Fluidity parameters of lipid regions determined by fluorescence polarization. Biochim. Biophys. Acta 515 (1978) 367-394
29. Parasassi T., De Stasio G., D'Ubaldo A., and Gratton E. Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence. Biophys. J. 57 (1990) 1179-1186
30. Parasassi T., De Stasio G., Ravagnan G., Rusch R.M., and Gratton E. Quantitation of lipid phases in phospholipids vescicles by the generalized polarization of Laurdan fluorescence. Biophys. J. 60 (1991) 179-189
31. Goldstein D.B. Effect of alcohol on cellular membranes. Ann. Emerg. Med. 15 (1986) 1013-1018
32. Lindi C., Marciani P., and Omedeo-Salè F. Age related changes in functions and physicochemical properties of rat jejunal brush border membrane after chronic ethanol administration. Comp. Biochem. Physiol. 104C (1993) 263-268
33. Wood W.G., and Schroeder F. Membrane effects of ethanol bulk lipid versus lipid domains. Life Sci. 43 6 (1988) 467-475
34. Berrettini M., Fedeli D., Falcioni G., Bevilacqua C., Massi M., and Polidori C. Hippocampal and striated skeletal miscele changes in fatty acid composition induced by ethanol in alcohol-preferring rats. Toxicology 199 (2004) 161-168
35. Borst J.W., Visser N.V., Kouptsova O., and Visser A.J.W.G. Oxidation of unsaturated phospholipids in membrane bilayer mixtures is accompagnated by membrane fluidity changes. Biochim. Biophys. Acta 1487 (2000) 61-73
36. Fedeli D., Fedeli A., Luciani F., Massi M., Falcioni G., and Polidori C. Lymphocyte DNA alteration by sub-chronic ethanol intake in alcohol-preferring rats. Clin. Chim. Acta 337 (2003) 43-48
37. Capel I.D., Willenbrock F., Jener M., and Williams D.C. The effect of ethanol ingestion on the erythrocyte antioxidant defense systems of rats. Biochem. Pharmacol. 29 (1980) 1737-1739
38. Orellana M., Rodrigo R., and Valdes E. Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. Gen. Pharmacol. 31 (1998) 817-820
39. Rodrigo R., Rivera G., Orellana M., Araya J., and Bosco C. Rat kidney antioxidant response to long-term exposure to flavonol rich red wine. Life Sci. 71 (2002) 2881-2895
40. Videla L.A., and Valenzuela A. Alcohol ingestion, liver glutathione and lipoperoxidation: metabolic interrelations and pathological implications. Life Sci. 31 (1982) 2395-2397
41. Roll F.S., Alexander M.A., Cua D., Swanson W., and Perez H.D. Metabolism of ethanol by rat hepatocytes results in generation of a lipid chemotactic factor: studies using a cell-free system and role of oxygen-derived free radicals. Arch. Biochem. Biophys. 287 (1991) 218-224
42. Montolin C., Valles S., Renau-Piqueras J., and Guerri C. Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: effect of chronic ethanol consumption. J. Neurochem. 63 (1994) 1855-1862
43. Parasassi T., Conti F., and Gratton E. Time-resolved fluorescence emission spectra of laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell. Mol. Biol. 32 (1986) 103-108
44. Sappington P.L., Cruz Jr. R.J., Harada T., Yang R., Han Y., Englert J.A., Ajami A.A., Killeen M.E., Delude R.L., and Fink M.P. The ethyl pyruvate analogues, diethyl oxaoproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro. Biochem. Pharmacol. 70 (2005) 1579-1592
45. Cevc G., and Marsh D. Phospholipid Bilayers, Physical Principles and Models (1987), Wiley, New York
46. Cladera J., and O'Shea P. Intramembrane molecular dipoles affect the membrane insertion and folding of a model amphiphilic peptide. Biophys. J. 74 (1998) 2434-2442
47. D. Fedeli, G. Falcioni, R. Olek, M. Massi, C. Cifani, C. Polidori, R. Gabbianelli, Protective effect of ethyl pyruvate on msP rat leukocytes damaged by alcohol intake. J. Appl. Toxicol. 27 (2007), in press.
48. Devamanoharan P.S., Henein M., Ali A.H., and Varma S.D. Attenuation of sugar cataract by ethyl pyruvate. Mol. Cell. Biochem. 200 (1999) 103-109
49. Wang L.Z., Sun W.C., and Zhu X.Z. Ethyl pyruvate protects PC12 cells from dopamine-induced apoptosis. Eur. J. Pharmacol. 508 (2005) 57-68