Part II: Bioavailability in beagle dogs of nimodipine solid dispersions prepared by hot-melt extrusion

Drug Development and Industrial Pharmacy

Volumn 33, Issue 7, 2007, Pages 783-789

  Zheng, Xin ^a   Yang, Rui ^a   Zhang, Yu ^a   Wang, Zhijun ^a   Tang, Xing ^a   Zheng, Liangyuan ^a,b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Building 4 ^*  (China)

Author keywords

Bioavailability; Dissolution; Hot melt extrusion; Nimodipine; Solid dispersion

Indexed keywords

ACRYLIC ACID ETHYL ESTER; AMINE; COPOLYMER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NIMODIPINE; POLY(METHYL METHACRYLATE); POLYMER; POVIDONE; VINYL ACETATE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DOG; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PHASE SEPARATION; X RAY POWDER DIFFRACTION;

ACRYLATES; ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CAPSULES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; DRUG CARRIERS; MALE; METHYLCELLULOSE; METHYLMETHACRYLATES; NIMODIPINE; POLYMERS; PYRROLIDINES; SOLUBILITY; TABLETS; VINYL COMPOUNDS;

EID: 34547143790     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040601050205     Document Type: Article

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