Characterization of the nitrosyl adduct of substrate-bound mouse cysteine dioxygenase by electron paramagnetic resonance: Electronic structure of the active site and mechanistic implications

Biochemistry

Volumn 46, Issue 29, 2007, Pages 8569-8578

  Pierce, Brad S ^a   Gardner, Jessica D ^a   Bailey, Lucas J ^a   Brunold, Thomas C ^a   Fox, Brian G ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN CYSTEINE DIOXYGENASE (CDO); MECHANISTIC IMPLICATIONS; NITROSYL ADDUCT;

AMINES; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRONIC STRUCTURE; ENZYMES; NITRIC OXIDE; SPECTROSCOPIC ANALYSIS;

MAMMALS;

3 MERCAPTOPROPIONIC ACID; AMINE; CARBOXYLIC ACID; CYSTEINE; CYSTEINE DIOXYGENASE; HISTIDINE; IRON; MERCAPTAMINE; NITRIC OXIDE; NITROGEN; OXYGEN; PROPANETHIOL; THIOL; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; CATALYSIS; CATALYST; COMPLEX FORMATION; CRYSTALLOGRAPHY; DENSITY FUNCTIONAL THEORY; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GEOMETRY; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN MOTIF; SIGNAL DETECTION;

ANIMALS; BINDING SITES; CATALYSIS; CYSTEINE; CYSTEINE DIOXYGENASE; ELECTRON SPIN RESONANCE SPECTROSCOPY; IRON; KINETICS; MICE; MODELS, MOLECULAR; NITRIC OXIDE; NITROGEN OXIDES; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 34547136935     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700662d     Document Type: Article

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