Human Chorionic Gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGβ transgenic female mice present with mammary gland tumors exhibiting characteristics of the Wnt/β-catenin pathway activation

Endocrinology

Volumn 148, Issue 8, 2007, Pages 3694-3703

  Kuorelahti, Aino ^a   Rulli, Susana ^a   Huhtaniemi, Ilpo ^a,b   Poutanen, Matti ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; UNCLASSIFIED DRUG; WINGLESS TYPE MMTV INTEGRATION SITE 5B; WINGLESS TYPE MMTV INTEGRATION SITE 7B; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; HORMONE ACTION; MAMMARY GLAND; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEROIDOGENESIS; TRANSGENIC MOUSE; TUMOR DIFFERENTIATION; UPREGULATION;

AGE FACTORS; ANIMALS; BETA CATENIN; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; ESTROGEN RECEPTOR ALPHA; FEMALE; GLYCOPROTEINS; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MYOEPITHELIOMA; OVARIECTOMY; PROTO-ONCOGENE PROTEINS; RECEPTORS, PROGESTERONE; UP-REGULATION; WNT PROTEINS;

EID: 34547114244     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0249     Document Type: Article

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