Prevention of TGF-β-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways

Apoptosis

Volumn 12, Issue 9, 2007, Pages 1659-1670

  Lin, Sue Jane ^a,b   Chang, Chungming ^a,b   Ng, Ah Kau ^b,c   Wang, Shu Han ^a   Li, Jia Je ^d   Hu, Cheng Po ^a,d,e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c UNIVERSITY OF SOUTHERN MAINE   (United States)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e TUNGHAI UNIVERSITY   (Taiwan)

Author keywords

Akt; Anti apoptosis; Hepatocellular carcinoma cells; IL 4; p70S6K; TGF

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; RAPAMYCIN; RECOMBINANT INTERLEUKIN 4; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; S6 KINASE; TRANSFORMING GROWTH FACTOR BETA; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CARBAZOLES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; HUMANS; INDOLES; INTERLEUKIN-4; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; PHOSPHOPROTEINS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SIROLIMUS; TRANSFORMING GROWTH FACTOR BETA;

EID: 34547107052     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0085-5     Document Type: Article

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