메뉴 건너뛰기




Volumn 13, Issue 14, 2007, Pages 4218-4224

The effect of repeated administration of cyclophosphamide on cytochrome P450 2B in rats

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; MESSENGER RNA;

EID: 34547096973     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-0320     Document Type: Article
Times cited : (9)

References (36)
  • 1
    • 0242320252 scopus 로고    scopus 로고
    • Ifosfamide and cyclophosphamide: Effects on immunosurveillance
    • Binotto G, Trentin L, Semenzato G. Ifosfamide and cyclophosphamide: effects on immunosurveillance. Oncology 2003;65:17-20.
    • (2003) Oncology , vol.65 , pp. 17-20
    • Binotto, G.1    Trentin, L.2    Semenzato, G.3
  • 2
    • 0035987892 scopus 로고    scopus 로고
    • The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes
    • Lindley C, Hamilton G, McCune JS, et al. The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes. Drug Metab Dispos 2002;30:814-22.
    • (2002) Drug Metab Dispos , vol.30 , pp. 814-822
    • Lindley, C.1    Hamilton, G.2    McCune, J.S.3
  • 3
    • 0023945947 scopus 로고
    • Metabolism of oxazaphosphorines
    • Sladek NE. Metabolism of oxazaphosphorines. Pharmacol Ther 1988;37:301-55.
    • (1988) Pharmacol Ther , vol.37 , pp. 301-355
    • Sladek, N.E.1
  • 4
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes
    • Chang TK, Weber GF, Crespi CL, Waxman DJ. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993;53:5629-37.
    • (1993) Cancer Res , vol.53 , pp. 5629-5637
    • Chang, T.K.1    Weber, G.F.2    Crespi, C.L.3    Waxman, D.J.4
  • 5
    • 0030799414 scopus 로고    scopus 로고
    • Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes
    • Ren S, Yang JS, Kalhorn TF, Slattery JT. Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes. Cancer Res 1997;57:4229-35.
    • (1997) Cancer Res , vol.57 , pp. 4229-4235
    • Ren, S.1    Yang, J.S.2    Kalhorn, T.F.3    Slattery, J.T.4
  • 6
    • 0033051029 scopus 로고    scopus 로고
    • Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles
    • Roy P, Yu LJ, Crespi CL, Waxman DJ. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos 1999;27:655-66.
    • (1999) Drug Metab Dispos , vol.27 , pp. 655-666
    • Roy, P.1    Yu, L.J.2    Crespi, C.L.3    Waxman, D.J.4
  • 7
    • 0033055342 scopus 로고    scopus 로고
    • In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: Impact on pharmacokinetics and antitumor activity
    • Yu LJ, Drewes P, Gustafsson K, Brain EG, Hecht JE, Waxman DJ. In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity. J Pharmacol Exp Ther 1999;288:928-37.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 928-937
    • Yu, L.J.1    Drewes, P.2    Gustafsson, K.3    Brain, E.G.4    Hecht, J.E.5    Waxman, D.J.6
  • 8
    • 1842845355 scopus 로고    scopus 로고
    • Harvesting of autologous blood stem cells after a mobilising regimen with low-dose cyclophosphamide
    • Deliliers GL, Annaloro C, Marconi M, et al. Harvesting of autologous blood stem cells after a mobilising regimen with low-dose cyclophosphamide. Leuk Lymphoma 2002;43:1957-60.
    • (2002) Leuk Lymphoma , vol.43 , pp. 1957-1960
    • Deliliers, G.L.1    Annaloro, C.2    Marconi, M.3
  • 9
    • 28444440311 scopus 로고    scopus 로고
    • High-dose versus low-dose cyclophosphamide in combination with G-CSF for peripheral blood progenitor cell mobilization
    • Ahn JS, Park S, Im SA, et al. High-dose versus low-dose cyclophosphamide in combination with G-CSF for peripheral blood progenitor cell mobilization. Korean J Intern Med 2005;20:224-31.
    • (2005) Korean J Intern Med , vol.20 , pp. 224-231
    • Ahn, J.S.1    Park, S.2    Im, S.A.3
  • 10
    • 0037370735 scopus 로고    scopus 로고
    • Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation
    • McDonald GB, Slattery JT, Bouvier ME, et al. Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood 2003;101:2043-8.
    • (2003) Blood , vol.101 , pp. 2043-2048
    • McDonald, G.B.1    Slattery, J.T.2    Bouvier, M.E.3
  • 12
    • 0025907234 scopus 로고
    • Pharmacokinetics of high-dose cyclophosphamide for bone marrow transplantation
    • Fasola G, Lo Greco P, Calori E, et al. Pharmacokinetics of high-dose cyclophosphamide for bone marrow transplantation. Haematologica 1991;76:120-5.
    • (1991) Haematologica , vol.76 , pp. 120-125
    • Fasola, G.1    Lo Greco, P.2    Calori, E.3
  • 13
    • 0023638209 scopus 로고
    • Repeated high-dose cyclophosphamide administration in bone marrow transplantation: Exposure to activated metabolites
    • Schuler U, Ehninger G, Wagner T. Repeated high-dose cyclophosphamide administration in bone marrow transplantation: exposure to activated metabolites. Cancer Chemother Pharmacol 1987;20:248-52.
    • (1987) Cancer Chemother Pharmacol , vol.20 , pp. 248-252
    • Schuler, U.1    Ehninger, G.2    Wagner, T.3
  • 15
    • 0032708007 scopus 로고    scopus 로고
    • A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients
    • Hassan M, Svensson US, Ljungman P, et al. A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients. Br J Clin Pharmacol 1999;48:669-77.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 669-677
    • Hassan, M.1    Svensson, U.S.2    Ljungman, P.3
  • 17
    • 0037315706 scopus 로고    scopus 로고
    • High-dose cyclophosphamide in multiple sclerosis patients undergoing autologous stem cell transplantation
    • McGuire TR, Gwilt P, Manouvilov K, et al. High-dose cyclophosphamide in multiple sclerosis patients undergoing autologous stem cell transplantation. Int Immunopharmacol 2003;3:279-83.
    • (2003) Int Immunopharmacol , vol.3 , pp. 279-283
    • McGuire, T.R.1    Gwilt, P.2    Manouvilov, K.3
  • 18
    • 0030951908 scopus 로고    scopus 로고
    • Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: Response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines
    • Chang TK, Yu L, Maurel P, Waxman DJ. Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines. Cancer Res 1997;57:1946-54.
    • (1997) Cancer Res , vol.57 , pp. 1946-1954
    • Chang, T.K.1    Yu, L.2    Maurel, P.3    Waxman, D.J.4
  • 19
    • 0032791111 scopus 로고    scopus 로고
    • Human CYP2B6: Expression, inducibility and catalytic activities
    • Gervot L, Rochat B, Gautier JC, et al. Human CYP2B6: expression, inducibility and catalytic activities. Pharmacogenetics 1999;9:295-306.
    • (1999) Pharmacogenetics , vol.9 , pp. 295-306
    • Gervot, L.1    Rochat, B.2    Gautier, J.C.3
  • 20
    • 0024994181 scopus 로고
    • Mechanisms of cyclophosphamide action on hepatic P-450 expression
    • LeBlanc GA, Waxman DJ. Mechanisms of cyclophosphamide action on hepatic P-450 expression. Cancer Res 1990;50:5720-6.
    • (1990) Cancer Res , vol.50 , pp. 5720-5726
    • LeBlanc, G.A.1    Waxman, D.J.2
  • 21
    • 0026740315 scopus 로고
    • Investigation of the mechanism by which cyclophosphamide alters cytochrome P450 in male rats
    • McClure MT, Stupans I. Investigation of the mechanism by which cyclophosphamide alters cytochrome P450 in male rats. Biochem Pharmacol 1992;43:2655-8.
    • (1992) Biochem Pharmacol , vol.43 , pp. 2655-2658
    • McClure, M.T.1    Stupans, I.2
  • 22
    • 0029037391 scopus 로고
    • Hormonal perturbation as a possible mechanism for the alteration of cytochrome P450 by cyclophosphamide
    • McClure MT, Stupans I. Hormonal perturbation as a possible mechanism for the alteration of cytochrome P450 by cyclophosphamide. Biochem Pharmacol 1995;49:1827-36.
    • (1995) Biochem Pharmacol , vol.49 , pp. 1827-1836
    • McClure, M.T.1    Stupans, I.2
  • 23
    • 0028862247 scopus 로고
    • Cyclophosphamide given repeatedly to the male rat and as a single dose to the female rat. Its effects on hepatic and pulmonary P450 and associated enzymes
    • Angley MT, Sansom LN, Stupans I. Cyclophosphamide given repeatedly to the male rat and as a single dose to the female rat. Its effects on hepatic and pulmonary P450 and associated enzymes. Xenobiotica 1995;25:1051-62.
    • (1995) Xenobiotica , vol.25 , pp. 1051-1062
    • Angley, M.T.1    Sansom, L.N.2    Stupans, I.3
  • 24
    • 0029935753 scopus 로고    scopus 로고
    • Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity
    • Kraner JC, Morgan ET, Poet TS, Born SL, Burnett VL, Halpert JR. Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity. J Pharmacol Exp Ther 1996;276:258-64.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 258-264
    • Kraner, J.C.1    Morgan, E.T.2    Poet, T.S.3    Born, S.L.4    Burnett, V.L.5    Halpert, J.R.6
  • 25
    • 20144366001 scopus 로고    scopus 로고
    • Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat
    • Xie H, Afsharian P, Terelius Y, et al. Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat. Xenobiotica 2005;35:239-51.
    • (2005) Xenobiotica , vol.35 , pp. 239-251
    • Xie, H.1    Afsharian, P.2    Terelius, Y.3
  • 26
    • 0037293651 scopus 로고    scopus 로고
    • Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin
    • Xie HJ, Broberg U, Griskevicius L, et al. Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin. Bone Marrow Transplant 2003;31:197-203.
    • (2003) Bone Marrow Transplant , vol.31 , pp. 197-203
    • Xie, H.J.1    Broberg, U.2    Griskevicius, L.3
  • 28
    • 0036001245 scopus 로고    scopus 로고
    • Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma
    • Griskevicius L, Meurling L, Hassan M. Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma. Ther Drug Monit 2002;24:405-9.
    • (2002) Ther Drug Monit , vol.24 , pp. 405-409
    • Griskevicius, L.1    Meurling, L.2    Hassan, M.3
  • 30
    • 0026748897 scopus 로고
    • Cyclophosphamide pharmacokinetics: Correlation with cardiac toxicity and tumor response
    • Ayash LJ, Wright JE, Tretyakov O, et al. Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and tumor response. J Clin Oncol 1992;10:995-1000.
    • (1992) J Clin Oncol , vol.10 , pp. 995-1000
    • Ayash, L.J.1    Wright, J.E.2    Tretyakov, O.3
  • 31
    • 0036016866 scopus 로고    scopus 로고
    • Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: Chemical-, cytochrome P450 isoform-, and cell-specific differences
    • Iwanari M, Nakajima M, Kizu R, Hayakawa K, Yokoi T. Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. Arch Toxicol 2002;76:287-98.
    • (2002) Arch Toxicol , vol.76 , pp. 287-298
    • Iwanari, M.1    Nakajima, M.2    Kizu, R.3    Hayakawa, K.4    Yokoi, T.5
  • 32
    • 0037369510 scopus 로고    scopus 로고
    • Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices
    • Edwards RJ, Price RJ, Watts PS, et al. Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices. Drug Metab Dispos 2003;31:282-8.
    • (2003) Drug Metab Dispos , vol.31 , pp. 282-288
    • Edwards, R.J.1    Price, R.J.2    Watts, P.S.3
  • 33
    • 0028790242 scopus 로고
    • Effect of cyclophosphamide administration on the activity and relative content of hepatic P4502D1 in rat
    • Laslett TJ, Alvarez F, Nation RL, Evans AM, Scott SD, Stupans I. Effect of cyclophosphamide administration on the activity and relative content of hepatic P4502D1 in rat. Xenobiotica 1995;25:1031-9.
    • (1995) Xenobiotica , vol.25 , pp. 1031-1039
    • Laslett, T.J.1    Alvarez, F.2    Nation, R.L.3    Evans, A.M.4    Scott, S.D.5    Stupans, I.6
  • 34
    • 0037450436 scopus 로고    scopus 로고
    • The expression of CYP2B6, CYP2C9 and CYP3A4 genes: A tangle of networks of nuclear and steroid receptors
    • Pascussi JM, Gerbal-Chaloin S, Drocourt L, Maurel P, Vilarem MJ. The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors. Biochim Biophys Acta 2003;1619:243-53.
    • (2003) Biochim Biophys Acta , vol.1619 , pp. 243-253
    • Pascussi, J.M.1    Gerbal-Chaloin, S.2    Drocourt, L.3    Maurel, P.4    Vilarem, M.J.5
  • 35
    • 0034685779 scopus 로고    scopus 로고
    • Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
    • Moore LB, Parks DJ, Jones SA, et al. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J Biol Chem 2000;275:15122-7.
    • (2000) J Biol Chem , vol.275 , pp. 15122-15127
    • Moore, L.B.1    Parks, D.J.2    Jones, S.A.3
  • 36
    • 33845881481 scopus 로고    scopus 로고
    • Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers
    • Faucette SR, Zhang TC, Moore R, et al. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. J Pharmacol Exp Ther 2007;320:72-80.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 72-80
    • Faucette, S.R.1    Zhang, T.C.2    Moore, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.