Amino acid changes within antenna helix are responsible for different regulatory preferences of human glutamate dehydrogenase isozymes

Journal of Biological Chemistry

Volumn 282, Issue 27, 2007, Pages 19510-19517

  Choi, Myung Min ^a   Kim, Eun A ^a   Yang, Seung Ju ^b   Soo, Young Choi ^c   Cho, Sung Woo ^a,d   Huh, Jae Wan ^a,d  

^a University of Ulsan College of Medicine   (South Korea)

^b Konyang University   (South Korea)

^c Hallym University   (South Korea)

^d NONE   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC REGULATION; GLUTAMATE DEHYDROGENASE ISOZYMES; REGULATORY PREFERENCES;

AMINO ACIDS; BIOMOLECULES; ENZYME INHIBITION; METABOLISM; MUTAGENESIS; TISSUE CULTURE;

PROTEINS;

ADENOSINE DIPHOSPHATE; CHIMERIC PROTEIN; GLUTAMATE DEHYDROGENASE; GLUTAMATE DEHYDROGENASE 1; GLUTAMATE DEHYDROGENASE 2; ISOENZYME; MUTANT PROTEIN; PALMITOYL COENZYME A; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME STABILITY; EVOLUTIONARY ADAPTATION; GEL MOBILITY SHIFT ASSAY; MAMMAL; METABOLISM; MUTATION; NERVOUS TISSUE; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; THERMOSTABILITY;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME STABILITY; EVOLUTION, MOLECULAR; GLUTAMATE DEHYDROGENASE; HUMANS; ISOENZYMES; MUTATION, MISSENSE; ORGAN SPECIFICITY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 34547093211     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703018200     Document Type: Article

References (43)

1. Yip, K. S. P., Stillman, T. J., Britton, K. L., Artymiuk, P. J., Baker, P. J., Sedelnikova, S. E., Engel, P. C., Pasquo, A., Chiaraluce, R., Consalvi, V., Scandurra, R., and Rice, D. W. (1995) Structure. 3, 1147-1158
2. Knapp, S., de Vos, W. M., Rice, D., and Ladenstein, R. (1997) J. Mol. Biol. 267, 916-932
3. Zaganas, I., and Plaitakis, A. (2002) J. Biol. Chem. 277, 26422-26428
4. Yang, S.-J., Huh, J.-W., Hong, H.-N., Kim, T. U., and Cho, S.-W. (2004) FEBS Lett. 562, 59-64
5. Mastorodemos, V., Zaganas, I., Spanaki, C., Bessa, M., and Plaitakis, A. (2005) J. Neurosci. Res. 79, 65-73
6. Kanavouras, K., Mastorodemos, V., Borompokas, N., Spanaki, C., and Plaitakis, A. (2007) J. Neurosci. Res. 85, 1101-1109
7. Smith, T. J., Schmidt, T., Fang, J., Wu, J., Siuzdak, G., and Stanley, C. A. (2002) J. Mol. Biol. 318, 765-777
8. Banerjee, S., Schmidt, T., Fang, J., Stanley, C. A., and Smith, T. J. (2003) Biochemistry 42, 3446-3456
9. Allen, A., Kwagh, J., Fang, J., Stanley, C. A., and Smith, T. J. (2004) Biochemistry 43, 14431-14443
10. Hussain, M. H., Zannis, V. I., and Plaitakis, A. (1989) J. Biol. Chem. 264, 20730-20735
11. Gorovitis, R., Avidan, N., Avisar, N., Shaked, I., and Vardimon, L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7024-7029
12. Plaitakis, A., and Shashidharan, P. (2000) J. Neurol. 247, Suppl. 2, 25-35
13. Stanley, C. A., Lieu, Y. K., Hus, B. Y., Burlina, A. B., Greenberg, C. R., Hopwood, N. J., Perlman, K., Rich, B. H., Zammarchi, E., and Ponoz, M. (1998) N. Engl. J. Med. 338, 1352-1357
14. Tanizawa, Y., Nakai, K., Sasaki, T., Anno, T., Ohta, Y., Inoue, H., Matsuo, K., Koga, M., Furukawa, S., and Oka, Y. (2002) Diabetes 51, 712-717
15. Shashidharan, P., Michaelidis, T. M., Robakis, N. K., Kresovali, A., Papamatheakis, J., and Plaitakis, A. (1994) J. Biol. Chem. 269, 16971-16976
16. Shashidharan, P., Clarke, D. D., Ahmed, N., Moschonas, N., and Plaitakis, A. (1997) J. Neurochem. 68, 1804-1811
17. Zaganas, I., Spanaki, C., Karpusas, M., and Plaitakis, A. (2002) J. Biol. Chem. 277, 46552-46558
18. Hanahan, D. (1983) J. Mol. Biol. 166, 557-580
19. Teller, J. K., Smith, R. J., McPherson, M. J., Engel, P. C., and Guest, J. R. (1992) Eur. J. Biochem. 206, 151-159
20. Studier, F. W., and Moffatt, B. A. (1986) J. Mol. Biol. 189, 113-130
21. Cho, S.-W., Yoon, H.-Y., Ahn, J.-Y., Lee, E.-Y., and Lee, J. (2001) Eur. J. Biochem. 268, 3205-3213
22. Jang, S. H., Kim, A. Y., Bahn, J. H., Eum, W. S., Kim, D. W., Park, J., Lee, K. S., Kang, T.-C., Won, M. H., Kang, J. H., Kwon, O.-S., Yoon, H.-Y., Lee, E.-Y., Cho, S.-W., and Choi, S. Y. (2003) Exp. Mol. Med. 35, 249-256
23. Bradford, M. (1976) Anal. Biochem. 72, 248-254
24. Fersht, A. (1985) Enzyme Structure and Mechanism, pp. 98-120, W. H. Freeman and Co., New York
25. Julliard, J., and Smith, E. L. (1979) J. Biol. Chem. 254, 3427-3438
26. Cho, S.-W., Ahn, J. Y., Lee, J., and Choi, S. Y. (1996) Biochemistry 35, 13907-13913
27. Lee, E. Y., Yoon, H. Y., Ahn, J. Y., Choi, S. Y., and Cho, S.-W. (2001) J. Biol. Chem. 276, 47930-47936
28. Burki, F., and Kaessmann, H. (2004) Nat. Genet. 36, 1061-1063
29. Plaitakis, A., Berl, S., and Yahr, M. D. (1982) Science 216, 193-196
30. Duvoisin, R. C., Chokroverty, S., Lepore, F., and Nicklas, W. J. (1983) Neurology 33, 1322-1326
31. Konagaya, Y., Konagaya, M., and Takayanagi, T. (1986) J. Neurol. Sci. 74, 231-236
32. Kajiyama, K., Ueno, S., Tatsumi, T., Yorifuji, S., Takahashi, M., and Tarui, S. (1988) J. Neurol. Neurosurg. Psychiatry 51, 1078-1080
33. Iwattsuji, K., Nakamura, S., and Kameyama, M. (1989) Gerontology 35, 218-224
34. Abe, T., Ishiguro, S. I., Saito, H., Kiyosawa, M., and Tamai, M. (1992) Investig. Ophthalmol. Vis. Sci. 33, 447-452
35. Fiermonte, G., Palmieri, L., Todisco, S., Agrimi, G., Palmieri, F., and Walker, J. E. (2002) J. Biol. Chem. 277, 19289-19294
36. Plaitakis, A., Spanaki, C., Mastorodemos, V., and Zaganas, I. (2003) Neurochem. Int. 43, 401-410
37. Peterson, P. E., and Smith, T. J. (1999) Structure 7, 769-782
38. Smith, T. J., Peterson, P. E., Schmidt, T., Fang J., and Stanley, C. A. (2001) J. Mol. Biol. 307, 707-720
39. Fang, J., Macmullen, C., Smith, T. J., and Stanley, C. A. (2002) Biochem. J. 363, 81-87
40. Stanley, C. A., Fang, J., Kutyna, K., Hsu, B. Y., Ming, J. E., Glaser, B., and Poncz, M. (2000) Diabetes 49, 667-673
41. MacMullenm, C., Fang, J., Hsu, B. Y. L., Kelly, A., DeLonlay-Debeney, P., Saudubray, J. M., Ganguly, A., Smith, T. J., and Stanley, C. A. (2001) J. Clin. Endocrinol. Metab. 86, 1782-1787
42. Cho, S.-W., Lee, J., and Choi, S. Y. (1995) Eur. J. Biochem. 233, 340-346
43. Plaitakis, A., and Zaganas, I. (2001) J. Neurosci. Res. 66, 899-908