ERK1/2 inactivation and p38 MAPK-dependent caspase activation during guanosine 5′-triphosphate-mediated terminal erythroid differentiation of K562 cells

International Journal of Biochemistry and Cell Biology

Volumn 39, Issue 9, 2007, Pages 1685-1697

  Moosavi, Mohammad Amin ^a   Yazdanparast, Razieh ^a   Lotfi, Abbas ^b  

^a UNIVERSITY OF TEHRAN   (Iran)

^b NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

Caspase; Erythroid differentiation; GTP; K562; p38 MAPK

Indexed keywords

CASPASE 3; CASPASE 6; CASPASE 9; CYTOCHROME C; GLYCOPHORIN A; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL XL;

ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG INHIBITION; ENZYME ACTIVATION; ERYTHROID CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

APOPTOSIS; CASPASES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; ERYTHROID CELLS; GUANOSINE TRIPHOSPHATE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; K562 CELLS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; TIME FACTORS;

EID: 34447619690     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.04.016     Document Type: Article

References (48)

1. Adrain C., Creagh E.M., and Martin S.J. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. EMBO J. 20 (2001) 6627-6636
2. Cao T., and Heng B.C. Differentiation therapy of cancer. Potential advantages over conventional therapeutic approaches targeting death of cancer/tumor cells. Med. Hypotheses 65 (2005) 1202-1203
3. Clarkson B., Strife A., Wisniewski D., Lambek C.L., and Liu C. Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies. Leukemia 17 (2003) 1211-1262
4. Czyz M., Szulawska A., Bednarek A.K., and Duchler M. Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation. Biochem. Pharmacol. 70 (2005) 1431-1442
5. Deming P.B., Schafer Z.T., Tashker J.S., Potts M.B., Deshmukh M., and Kornbluth S. Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release. Mol. Cell. Biol. 24 (2004) 10289-10299
6. Di Bacco A.M., and Cotter T.G. p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases. Br. J. Haematol. 117 (2002) 588-597
7. Di Pietro R., di Giacomo V., Caravatta L., Sancilio S., Rana R.A., and Catald i.A. Cyclic nucleotide response element binding (CREB) protein activation is involved in K562 erythroleukemia cells differentiation. J. Cell. Biochem. 11 (2007) 1070-1079
8. Drexler H.C., and Pebler S. Inducible p27 (Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors. Cell Death Differ. 10 (2003) 290-301
9. Gregoli P.A., and Bondurant M.C. Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors. J. Cell. Physiol. 178 (1999) 133-143
10. Huang H.M., Chiou H.Y., and Chang J.L. Activin A induces erythroid gene expressions and inhibits mitogenic cytokine-mediated K562 colony formation by activating p38 MAPK. J. Cell Biochem. 98 (2006) 789-797
11. Ikeda A., Shankar D.B., Watanabe M., Tamanoi F., Moore T.B., and Sakamoto K.M. Molecular targets and the treatment of myeloid leukemia. Mol. Genet. Metab. 88 (2006) 216-224
12. Jacquel A., Colosetti P., Grosso S., Belhacene N., Puissant A., Marchetti S., et al. Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition. Oncogene 26 (2007) 2445-2458
13. Jacquel A., Herrant M., Legros L., Belhacene N., Luciano F., Pages G., et al. Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl positive K562 cell line and its differentiation towards the erythroid lineage. FASEB J. 17 (2003) 2160-2162
14. Koeffler H.B., and Golde D.W. Human myeloid leukemia cell lines: A review. Blood 56 (1980) 344-350
15. Kohmura K., Miyakawa Y., Kawai Y., Ikeda Y., and Kizaki M. Different roles of p38 MAPK and ERK in STI571-induced multi-lineage differentiation of K562 cells. J. Cell. Physiol. 198 (2004) 370-376
16. Kolbous A., Pilat S., Husak Z., Deiner E.M., Stengl G., Beug H., et al. Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J. Exp. Med. 196 (2002) 1347-1353
17. Law J.C., Ritke M.K., Yalowich J.C., Leder G.H., and Ferrell R.E. Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line. Leuk. Res. 17 (1993) 1045-1050
18. Lozzio B.B., and Lozzio C.B. Properties of the K562 cell line derived from a patient with choronic myeloid leukemia. Int. J. Cancer 19 (1977) 136
19. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
20. Maquarre E., Artus C., Gadhoum Z., Jasmin C., Smadja-Joffe F., and Robert-Lezenes J. CD44 ligation induces apoptosis via caspase- and serine protease-dependent pathways in acute promyelocytic leukemia cells. Leukemia 19 (2005) 2296-2303
21. Mauro M.J., and Deininger M.W. Chronic myeloid leukemia in 2006: A perspective. Heamatologica 91 (2006) 152-157
22. Meinhardt G., Roth J., and Hass R. Activation of protein kinase C relays distinct signaling pathways in the same cell type: Differentiation and caspase-mediated apoptosis. Cell Death Differ. 7 (2000) 795-803
23. Moosavi M.A., and Yazdanparast R. Differentiation therapy as an effective strategy for the treatment of chronic myelogenous leukemia. Med. Hypotheses 67 (2006) 1470-1471
24. Moosavi M.A., Yazdanparast R., and Lotfi A. GTP induces S-phase cell-cycle arrest and inhibits DNA synthesis in K562 cells but not in normal human peripheral lymphocytes. J. Biochem. Mol. Biol. 39 (2006) 492-501
25. Morceau F., Aries A., Lahlil R., Devy L., Jardillier J.C., Leannesson P., et al. Evidence for distinct regulation processes in the aclacinomycin- and doxorubicin-mediated differentiation of human erythroleukemic cells. Biochem. Pharmacol. 51 (1996) 839-845
26. Morceau F., Dupont C., Palissot V., Borde-Chiche P., Trentesaux C., Dicato M., et al. GTP-mediated differentiation of the human K562 cell line: Transient overexpression of GATA-1 and stabilization of the gamma-globin mRNA. Leukemia 14 (2000) 1589-1597
27. Nagata Y., Takahashi N., Davis R.J., and Todokoro K. Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation. Blood 92 (1998) 1859-1869
28. Osti F., Corradini F.G., Hanau S., Matteuzzi M., and Gambari R. Human leukemia K562 cells: Induction of erythriod differentiation by guanine, guanosine and guanine nucleotides. Haematologica 82 (1997) 395-401
29. O'Brien S.G., Guilhot F., Larson R.A., Gathmann I., Baccarani M., Cervantes F., et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N. Engl. J. Med. 348 (2003) 994-1004
30. Olson N.E., Graves J.D., Shu G.L., Ryan E.J., and Clark E.A. Caspase activity is required for stimulated B lymphocytes to enter the cell cycle. J. Immunol. 170 (2003) 6065-6072
31. Park J.I., Choi H.S., Jeong J.S., Han J.Y., and Kim I.H. Involvement of p38 kinase in hydroxyurea-induced differentiation of K562 cells. Cell Growth Differ. 12 (2001) 481-486
32. Pearson G., Robinson F., Beers Gibson T., Xu B.E., Karandikar M., Berman K., et al. Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions. Endocrinol. Rev. 22 (2001) 153-183
33. Platanias L.C. Map kinase signaling pathways and hematologic malignancies. Blood 101 (2003) 4667-4679
34. Ribeil J.A., Zermati Y., Vandekerckhove J., Cathelin S., Kersual J., Dussiot M., et al. Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1. Nature 445 (2007) 102-105
35. Schewerk C., and Schulz-Osthoff K. Non-apoptotic function of caspases in cellular proliferation and differentiation. Biochem. Pharmacol. 66 (2003) 1453-1458
36. Sell S. Cancer stem cells and differentiation therapy. Tumour Biol. 27 (2006) 59-70
37. Sordet O., Rabe C., Planchatee S., Zermati Y., Hermine O., Valnchenker W., et al. Specific involvement of caspases in the differentiation of monocytes into macrophages. Blood 100 (2002) 4446-4452
38. Steelman L.S., Pohner t.S.C., Shelton J.G., Franklin R.A., Bertrand F.E., and McCurby J.A. JAK/STAT, Raf/MEK/ERK, PH3K/Akt and BCR-ABL in cell cycle progression and leukemogeneses. Leukemia 18 (2004) 189-218
39. Villeva J.L., Pelicci P.G., Tabilio A., Titeux M., Houesche A.F., Thomopoulos P., et al. Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction. Exp. Cell Res. 146 (1983) 428-435
40. Weidmann M., Smith D.H., and Carille G. Caspase-3 has a nonapoptotic function in erythroid maturation. Blood 103 (2004) 4310-4317
41. Wetzler M., Talpaz M., Van Etten R.A., Hirsh-Ginsberg C., Beran M., and Kurzrock R. Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation. J. Clin. Invest. 92 (1993) 1925-1939
42. Wiernik P., Dutcher J., Paietta E., Hittelman W., Vyas R., Strack M., et al. Treatment of promyelocytic blast crisis of chronic myelogenous leukemia with all trans-retinoic acid. Leukemia 5 (1991) 504-509
43. Witt O., Monkemeyer S., Kanbach K.A., and Pekrun A. Induction of fetal hemoglobin synthesis by valproate: Modulation of MAP kinases pathway. Am. J. Hematol. 71 (2002) 45-46
44. Witt O., Monkemeyer S., Ronndahl G., Erdlenbruch B., Reinhardt D., Kanbach K., et al. Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. Blood 101 (2003) 2001-2007
45. Witt O., Sand K., and Pekrun A. Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways. Blood 95 (2000) 2391-2396
46. Wong S., and Witte O.N. The BCR-ABL story: Bench to bedside and back. Annu. Rev. Immunol. 22 (2004) 247-306
47. Yazdanparast R., Moosavi M.A., Mahdavi M., and Lotfi A. GTP induces differentiation and apoptosis in human leukemia KG1 and U937 cells. Acta Pharm. Sinica 27 (2006) 1175-1184
48. Zermati B.Y., Garrido C., Amsellem S., Fishelson S., Bouscary D., Valensi F., et al. Caspase activation is required for terminal erythroid differentiation. J. Exp. Med. 193 (2001) 247-254