Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Volumn 17, Issue 14, 2003, Pages 2160-2162

  Jacquel, Arnaud ^a   Herrant, Magali ^a   Legros, Laurence ^a   Belhacene, Nathalie ^a   Luciano, Frederic ^a   Pages, Gilles ^a   Hofman, Paul ^a   Auberger, Patrick ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; ENZYME INHIBITOR; IMATINIB; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL LINEAGE; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; DNA MICROARRAY; DRUG ANTAGONISM; DRUG EFFECT; ERYTHROID PRECURSOR CELL; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINEAGE; ENZYME INHIBITORS; ERYTHROID PROGENITOR CELLS; FUSION PROTEINS, BCR-ABL; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; MITOCHONDRIA; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; SIGNAL TRANSDUCTION;

EID: 0642303647     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.03-0322fje     Document Type: Article

References (0)