-
1
-
-
2342618233
-
Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies
-
Bruyere O., Pavelka K., Rovati L.C., Deroisy R., Olejarova M., Gatterova J., Giacovelli G., and Reginster J.Y. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies. Menopause 11 (2004) 138-143
-
(2004)
Menopause
, vol.11
, pp. 138-143
-
-
Bruyere, O.1
Pavelka, K.2
Rovati, L.C.3
Deroisy, R.4
Olejarova, M.5
Gatterova, J.6
Giacovelli, G.7
Reginster, J.Y.8
-
2
-
-
1242308859
-
Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate
-
Christgau S., Henrotin Y., Tanko L.B., Rovati L.C., Collette J., Bruyere O., Deroisy R., and Reginster J.Y. Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate. Clin. Exp. Rheumatol. 22 (2004) 36-42
-
(2004)
Clin. Exp. Rheumatol.
, vol.22
, pp. 36-42
-
-
Christgau, S.1
Henrotin, Y.2
Tanko, L.B.3
Rovati, L.C.4
Collette, J.5
Bruyere, O.6
Deroisy, R.7
Reginster, J.Y.8
-
3
-
-
0010982856
-
Inhibition of tumour growth by d-glucosamine
-
Quastel J.H., and Cantero A. Inhibition of tumour growth by d-glucosamine. Nature 171 (1953) 252-254
-
(1953)
Nature
, vol.171
, pp. 252-254
-
-
Quastel, J.H.1
Cantero, A.2
-
4
-
-
0014468654
-
Inhibitory effect of d-glucosamine and other sugar analogs on the viability and transplantability of ascites tumor cells
-
Bekesi J.G., Molnar Z., and Winzler R.J. Inhibitory effect of d-glucosamine and other sugar analogs on the viability and transplantability of ascites tumor cells. Cancer Res. 29 (1969) 353-359
-
(1969)
Cancer Res.
, vol.29
, pp. 353-359
-
-
Bekesi, J.G.1
Molnar, Z.2
Winzler, R.J.3
-
5
-
-
0014891485
-
Inhibitory effects of d-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis
-
Bekesi J.G., and Winzler R.J. Inhibitory effects of d-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis. Cancer Res. 30 (1970) 2905-2912
-
(1970)
Cancer Res.
, vol.30
, pp. 2905-2912
-
-
Bekesi, J.G.1
Winzler, R.J.2
-
6
-
-
0018886244
-
Membrane-active drugs potentiate the killing of tumor cells by d-glucosamine
-
Friedman S.J., and Skehan P. Membrane-active drugs potentiate the killing of tumor cells by d-glucosamine. Proc. Natl. Acad. Sci. USA 77 (1980) 1172-1176
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1172-1176
-
-
Friedman, S.J.1
Skehan, P.2
-
7
-
-
0021349139
-
d-Glucosamine-induced changes in nucleotide metabolism and growth of colon-carcinoma cells in culture
-
Krug E., Zweibaum A., Schulz-Holstege C., and Keppler D. d-Glucosamine-induced changes in nucleotide metabolism and growth of colon-carcinoma cells in culture. Biochem. J. 217 (1984) 701-708
-
(1984)
Biochem. J.
, vol.217
, pp. 701-708
-
-
Krug, E.1
Zweibaum, A.2
Schulz-Holstege, C.3
Keppler, D.4
-
8
-
-
0014690652
-
Inhibitory effect of d-glucosamine and other sugars on the biosynthesis of protein, ribonucleic acid, and deoxyribonucleic acid in normal and neoplastic tissues
-
Bekesi J.G., Bekesi E., and Winzler R.J. Inhibitory effect of d-glucosamine and other sugars on the biosynthesis of protein, ribonucleic acid, and deoxyribonucleic acid in normal and neoplastic tissues. J. Biol. Chem. 244 (1969) 3766-3772
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 3766-3772
-
-
Bekesi, J.G.1
Bekesi, E.2
Winzler, R.J.3
-
9
-
-
0015230188
-
Inhibition of protein, glycoprotein, ribonucleic acid and deoxyribonucleic acid synthesis by d-glucosamine and other sugars in mouse leukemic cells L5178Y and selective inhibition in SV-3T3 compared with 3T3 cells
-
Bosmann H.B. Inhibition of protein, glycoprotein, ribonucleic acid and deoxyribonucleic acid synthesis by d-glucosamine and other sugars in mouse leukemic cells L5178Y and selective inhibition in SV-3T3 compared with 3T3 cells. Biochim. Biophys. Acta 240 (1971) 74-93
-
(1971)
Biochim. Biophys. Acta
, vol.240
, pp. 74-93
-
-
Bosmann, H.B.1
-
10
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N., and Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 18 (2004) 1926-1945
-
(2004)
Genes Dev.
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
11
-
-
33745150462
-
Ribosomal protein S6 phosphorylation: from protein synthesis to cell size
-
Ruvinsky I., and Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem. Sci. 31 (2006) 342-348
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 342-348
-
-
Ruvinsky, I.1
Meyuhas, O.2
-
12
-
-
0036119219
-
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1
-
Radimerski T., Montagne J., Rintelen F., Stocker H., van der Kaay J., Downes C.P., Hafen E., and Thomas G. dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nat. Cell Biol. 4 (2002) 251-255
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 251-255
-
-
Radimerski, T.1
Montagne, J.2
Rintelen, F.3
Stocker, H.4
van der Kaay, J.5
Downes, C.P.6
Hafen, E.7
Thomas, G.8
-
13
-
-
0035787712
-
Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs
-
Hornstein E., Tang H., and Meyuhas O. Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs. Cold Spring Harb. Symp. Quant. Biol. 66 (2001) 477-484
-
(2001)
Cold Spring Harb. Symp. Quant. Biol.
, vol.66
, pp. 477-484
-
-
Hornstein, E.1
Tang, H.2
Meyuhas, O.3
-
14
-
-
4043050174
-
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells
-
Gao N., Flynn D.C., Zhang Z., Zhong X.S., Walker V., Liu K.J., Shi X., and Jiang B.H. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am. J. Physiol. Cell Physiol. 287 (2004) C281-C291
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Gao, N.1
Flynn, D.C.2
Zhang, Z.3
Zhong, X.S.4
Walker, V.5
Liu, K.J.6
Shi, X.7
Jiang, B.H.8
-
15
-
-
18644380648
-
Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells
-
Lee J.E., Kim K.M., Cho J.W., Suh S.I., Suh M.H., Kwon T.K., Park J.W., Bae J.H., Song D.K., Cho C.H., Bae I., and Baek W.K. Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells. Biochem. Biophys. Res. Commun. 298 (2002) 230-234
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.298
, pp. 230-234
-
-
Lee, J.E.1
Kim, K.M.2
Cho, J.W.3
Suh, S.I.4
Suh, M.H.5
Kwon, T.K.6
Park, J.W.7
Bae, J.H.8
Song, D.K.9
Cho, C.H.10
Bae, I.11
Baek, W.K.12
-
16
-
-
0037300799
-
A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance
-
Wells L., Vosseller K., and Hart G.W. A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance. Cell Mol. Life Sci. 60 (2003) 222-228
-
(2003)
Cell Mol. Life Sci.
, vol.60
, pp. 222-228
-
-
Wells, L.1
Vosseller, K.2
Hart, G.W.3
-
17
-
-
0141884304
-
Dynamic interplay between O-GlcNAc and O-phosphate: the sweet side of protein regulation
-
Slawson C., and Hart G.W. Dynamic interplay between O-GlcNAc and O-phosphate: the sweet side of protein regulation. Curr. Opin. Struct. Biol. 13 (2003) 631-636
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 631-636
-
-
Slawson, C.1
Hart, G.W.2
-
18
-
-
2542453754
-
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells
-
Andreozzi F., D'Alessandris C., Federici M., Laratta E., Del Guerra S., Del Prato S., Marchetti P., Lauro R., Perticone F., and Sesti G. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. Endocrinology 145 (2004) 2845-2857
-
(2004)
Endocrinology
, vol.145
, pp. 2845-2857
-
-
Andreozzi, F.1
D'Alessandris, C.2
Federici, M.3
Laratta, E.4
Del Guerra, S.5
Del Prato, S.6
Marchetti, P.7
Lauro, R.8
Perticone, F.9
Sesti, G.10
-
19
-
-
0037117511
-
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes
-
Vosseller K., Wells L., Lane M.D., and Hart G.W. Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc. Natl. Acad. Sci. USA 99 (2002) 5313-5318
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5313-5318
-
-
Vosseller, K.1
Wells, L.2
Lane, M.D.3
Hart, G.W.4
-
20
-
-
0035099711
-
Glucose-induced insulin resistance of phosphatidylinositol 3'-OH kinase and AKT/PKB is mediated by the hexosamine biosynthesis pathway
-
Singh L.P., Gennerette D., Simmons S., and Crook E.D. Glucose-induced insulin resistance of phosphatidylinositol 3'-OH kinase and AKT/PKB is mediated by the hexosamine biosynthesis pathway. J. Diabetes Complications 15 (2001) 88-96
-
(2001)
J. Diabetes Complications
, vol.15
, pp. 88-96
-
-
Singh, L.P.1
Gennerette, D.2
Simmons, S.3
Crook, E.D.4
-
21
-
-
0029081544
-
Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites
-
Han J.W., Pearson R.B., Dennis P.B., and Thomas G. Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites. J. Biol. Chem. 270 (1995) 21396-21403
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21396-21403
-
-
Han, J.W.1
Pearson, R.B.2
Dennis, P.B.3
Thomas, G.4
-
22
-
-
0028802451
-
The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain
-
Pearson R.B., Dennis P.B., Han J.W., Williamson N.A., Kozma S.C., Wettenhall R.E., and Thomas G. The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. EMBO J. 14 (1995) 5279-5287
-
(1995)
EMBO J.
, vol.14
, pp. 5279-5287
-
-
Pearson, R.B.1
Dennis, P.B.2
Han, J.W.3
Williamson, N.A.4
Kozma, S.C.5
Wettenhall, R.E.6
Thomas, G.7
-
23
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
Pullen N., Dennis P.B., Andjelkovic M., Dufner A., Kozma S.C., Hemmings B.A., and Thomas G. Phosphorylation and activation of p70s6k by PDK1. Science 279 (1998) 707-710
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
Hemmings, B.A.6
Thomas, G.7
-
24
-
-
0027336002
-
p70s6k function is essential for G1 progression
-
Lane H.A., Fernandez A., Lamb N.J., and Thomas G. p70s6k function is essential for G1 progression. Nature 363 (1993) 170-172
-
(1993)
Nature
, vol.363
, pp. 170-172
-
-
Lane, H.A.1
Fernandez, A.2
Lamb, N.J.3
Thomas, G.4
-
25
-
-
0345732640
-
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
-
Fingar D.C., Richardson C.J., Tee A.R., Cheatham L., Tsou C., and Blenis J. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell Biol. 24 (2004) 200-216
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 200-216
-
-
Fingar, D.C.1
Richardson, C.J.2
Tee, A.R.3
Cheatham, L.4
Tsou, C.5
Blenis, J.6
-
26
-
-
33748538728
-
Glucosamine sulfate-induced apoptosis in chronic myelogenous leukemia K562 cells is associated with translocation of cathepsin D and downregulation of Bcl-xL
-
Wang Z., Liang R., Huang G.S., Piao Y., Zhang Y.Q., Wang A.Q., Dong B.X., Feng J.L., Yang G.R., and Guo Y. Glucosamine sulfate-induced apoptosis in chronic myelogenous leukemia K562 cells is associated with translocation of cathepsin D and downregulation of Bcl-xL. Apoptosis 11 (2006) 1851-1860
-
(2006)
Apoptosis
, vol.11
, pp. 1851-1860
-
-
Wang, Z.1
Liang, R.2
Huang, G.S.3
Piao, Y.4
Zhang, Y.Q.5
Wang, A.Q.6
Dong, B.X.7
Feng, J.L.8
Yang, G.R.9
Guo, Y.10
-
27
-
-
20544441287
-
Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides
-
Masson E., Wiernsperger N., Lagarde M., and El Bawab S. Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides. Biochem. J. 388 (2005) 537-544
-
(2005)
Biochem. J.
, vol.388
, pp. 537-544
-
-
Masson, E.1
Wiernsperger, N.2
Lagarde, M.3
El Bawab, S.4
-
28
-
-
0026757270
-
An array of insulin-activated proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase
-
Mukhopadhyay N.K., Price D.J., Kyriakis J.M., Pelech S., Sanghera J., and Avruch J. An array of insulin-activated proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J. Biol. Chem. 267 (1992) 3325-3335
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3325-3335
-
-
Mukhopadhyay, N.K.1
Price, D.J.2
Kyriakis, J.M.3
Pelech, S.4
Sanghera, J.5
Avruch, J.6
-
29
-
-
0029658805
-
The p70S6K signalling pathway: a novel signalling system involved in growth regulation
-
Grammer T.C., Cheatham L., Chou M.M., and Blenis J. The p70S6K signalling pathway: a novel signalling system involved in growth regulation. Cancer Surv. 27 (1996) 271-292
-
(1996)
Cancer Surv.
, vol.27
, pp. 271-292
-
-
Grammer, T.C.1
Cheatham, L.2
Chou, M.M.3
Blenis, J.4
-
30
-
-
0032932198
-
p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex
-
Romanelli A., Martin K.A., Toker A., and Blenis J. p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex. Mol. Cell Biol. 19 (1999) 2921-2928
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 2921-2928
-
-
Romanelli, A.1
Martin, K.A.2
Toker, A.3
Blenis, J.4
-
31
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P.E., Barrow R.K., Cohen N.A., Snyder S.H., and Sabatini D.M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. USA 95 (1998) 1432-1437
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
32
-
-
0033607531
-
Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro
-
Isotani S., Hara K., Tokunaga C., Inoue H., Avruch J., and Yonezawa K. Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. J. Biol. Chem. 274 (1999) 34493-34498
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34493-34498
-
-
Isotani, S.1
Hara, K.2
Tokunaga, C.3
Inoue, H.4
Avruch, J.5
Yonezawa, K.6
-
33
-
-
0029828590
-
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
-
Dennis P.B., Pullen N., Kozma S.C., and Thomas G. The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol. Cell Biol. 16 (1996) 6242-6251
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 6242-6251
-
-
Dennis, P.B.1
Pullen, N.2
Kozma, S.C.3
Thomas, G.4
-
34
-
-
33750072949
-
mTOR and cancer therapy
-
Easton J.B., and Houghton P.J. mTOR and cancer therapy. Oncogene 25 (2006) 6436-6446
-
(2006)
Oncogene
, vol.25
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
|