-
1
-
-
0030025660
-
Replicative senescence: An old lives' tale?
-
Campisi J. Replicative senescence: An old lives' tale? Cell 1996: 84: 497-500.
-
(1996)
Cell
, vol.84
, pp. 497-500
-
-
Campisi, J.1
-
2
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour C M, Krtolica A, Galimi F et al. Reversal of human cellular senescence: Roles of the p53 and p16 pathways. EMBO J 2003: 22: 4212-4222.
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
-
3
-
-
0028261160
-
Escape from senescence in human diploid fibroblasts induced directly by mutant p53
-
Bond J A, Wyllie F S, Wynford-Thomas D. Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene 1994: 9: 1885-1889.
-
(1994)
Oncogene
, vol.9
, pp. 1885-1889
-
-
Bond, J.A.1
Wyllie, F.S.2
Wynford-Thomas, D.3
-
4
-
-
0037461928
-
Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells
-
Ramirez R D, Herbert B S, Vaughan M B et al. Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells. Oncogene 2003: 22: 433-444.
-
(2003)
Oncogene
, vol.22
, pp. 433-444
-
-
Ramirez, R.D.1
Herbert, B.S.2
Vaughan, M.B.3
-
5
-
-
0036288508
-
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
-
Rheinwald J G, Hahn W C, Ramsey M R et al. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol 2002: 22: 5157-5172.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5157-5172
-
-
Rheinwald, J.G.1
Hahn, W.C.2
Ramsey, M.R.3
-
6
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
Shay J W, Pereira-Smith O M, Wright W E. A role for both RB and p53 in the regulation of human cellular senescence. Exp Cell Res 1991: 196: 33-39.
-
(1991)
Exp Cell Res
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
7
-
-
0029894237
-
Telomere length regulation
-
Greider C W. Telomere length regulation. Annu Rev Biochem 1996: 65: 337-365.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
8
-
-
0031000884
-
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
-
Makarov V L, Hirose Y, Langmore J P. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 1997: 88: 657-666.
-
(1997)
Cell
, vol.88
, pp. 657-666
-
-
Makarov, V.L.1
Hirose, Y.2
Langmore, J.P.3
-
9
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith J D, Comeau L, Rosenfield S et al. Mammalian telomeres end in a large duplex loop. Cell 1999: 97: 503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
-
10
-
-
0037148277
-
Protection of mammalian telomeres
-
de Lange T. Protection of mammalian telomeres. Oncogene 2002: 21: 532-540.
-
(2002)
Oncogene
, vol.21
, pp. 532-540
-
-
de Lange, T.1
-
11
-
-
0037148278
-
Telomere dysfunction: Multiple paths to the same end
-
Harrington L, Robinson M O. Telomere dysfunction: Multiple paths to the same end. Oncogene 2002: 21: 592-597.
-
(2002)
Oncogene
, vol.21
, pp. 592-597
-
-
Harrington, L.1
Robinson, M.O.2
-
12
-
-
0037192462
-
Senescence induced by altered telomere state, not telomere loss
-
Karlseder J, Smogorzewska A, de Lange T. Senescence induced by altered telomere state, not telomere loss. Science 2002: 295: 2446-2449.
-
(2002)
Science
, vol.295
, pp. 2446-2449
-
-
Karlseder, J.1
Smogorzewska, A.2
de Lange, T.3
-
13
-
-
0033605145
-
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
-
Karlseder J, Broccoli D, Dai Y, Hardy S, de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science 1999: 283: 1321-1325. 1321-1325.
-
(1999)
Science
, vol.283
, pp. 1321-1325
-
-
Karlseder, J.1
Broccoli, D.2
Dai, Y.3
Hardy, S.4
de Lange, T.5
-
14
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003: 13: 1549-1556.
-
(2003)
Curr Biol
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
de Lange, T.3
-
15
-
-
27944496124
-
Functional human telomeres are recognized as DNA damage in g2 of the cell cycle
-
Verdun R E, Crabbe L, Haggblom C, Karlseder J. Functional human telomeres are recognized as DNA damage in g2 of the cell cycle. Mol Cell 2005: 20: 551-561.
-
(2005)
Mol Cell
, vol.20
, pp. 551-561
-
-
Verdun, R.E.1
Crabbe, L.2
Haggblom, C.3
Karlseder, J.4
-
16
-
-
33750801681
-
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
-
Verdun R E, Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 2006: 127: 709-720.
-
(2006)
Cell
, vol.127
, pp. 709-720
-
-
Verdun, R.E.1
Karlseder, J.2
-
18
-
-
0027732667
-
Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes
-
Abdel-Malek Z, Swope V, Collins C, Boissy R, Zhao H, Nordlund J. Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes. J Cell Sci 1993: 4: 1323-1331.
-
(1993)
J Cell Sci
, vol.4
, pp. 1323-1331
-
-
Abdel-Malek, Z.1
Swope, V.2
Collins, C.3
Boissy, R.4
Zhao, H.5
Nordlund, J.6
-
19
-
-
0025362506
-
The relationship between tyrosinase activity and skin color in human foreskins
-
Iwata M, Corn T, Iwata S, Everett M A, Fuller B B. The relationship between tyrosinase activity and skin color in human foreskins. J Invest Dermatol 1990: 95: 9-15.
-
(1990)
J Invest Dermatol
, vol.95
, pp. 9-15
-
-
Iwata, M.1
Corn, T.2
Iwata, S.3
Everett, M.A.4
Fuller, B.B.5
-
20
-
-
0041835985
-
Cutaneous photobiology. The melanocyte vs. the sun: Who will win the final round?
-
Kadekaro A L, Kavanagh R J, Wakamatsu K, Ito S, Pipitone M A, Abdel-Malek Z A. Cutaneous photobiology. The melanocyte vs. the sun: Who will win the final round? Pigment Cell Res 2003: 16: 434-447.
-
(2003)
Pigment Cell Res
, vol.16
, pp. 434-447
-
-
Kadekaro, A.L.1
Kavanagh, R.J.2
Wakamatsu, K.3
Ito, S.4
Pipitone, M.A.5
Abdel-Malek, Z.A.6
-
22
-
-
0024379332
-
Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light
-
Freeman S E, Hacham H, Gange R W, Maytum D J, Sutherland J C, Sutherland B M. Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light. Proc Natl Acad Sci U S A 1989: 86: 5605-5609.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 5605-5609
-
-
Freeman, S.E.1
Hacham, H.2
Gange, R.W.3
Maytum, D.J.4
Sutherland, J.C.5
Sutherland, B.M.6
-
24
-
-
0027442806
-
Treatment of human melanocytes and S91 melanoma cells with the DNA repair enzyme T4 endonuclease V enhances melanogenesis after ultraviolet irradiation
-
Gilchrest B A, Zhai S, Eller M S, Yarosh D B, Yaar M. Treatment of human melanocytes and S91 melanoma cells with the DNA repair enzyme T4 endonuclease V enhances melanogenesis after ultraviolet irradiation. J Invest Dermatol 1993: 101: 666-672.
-
(1993)
J Invest Dermatol
, vol.101
, pp. 666-672
-
-
Gilchrest, B.A.1
Zhai, S.2
Eller, M.S.3
Yarosh, D.B.4
Yaar, M.5
-
25
-
-
33847422145
-
Central role of p53 in the suntan response and pathologic hyperpigmentation
-
Cui R, Widlund H R, Feige E et al. Central role of p53 in the suntan response and pathologic hyperpigmentation. Cell 2007: 128: 853-864.
-
(2007)
Cell
, vol.128
, pp. 853-864
-
-
Cui, R.1
Widlund, H.R.2
Feige, E.3
-
27
-
-
0030115051
-
Tumor suppressor p53 down-regulates tissue-specific expression of tyrosinase gene in human melanoma cell lines
-
Kichina J, Green A, Rauth S. Tumor suppressor p53 down-regulates tissue-specific expression of tyrosinase gene in human melanoma cell lines. Pigment Cell Res 1996: 9: 85-91.
-
(1996)
Pigment Cell Res
, vol.9
, pp. 85-91
-
-
Kichina, J.1
Green, A.2
Rauth, S.3
-
28
-
-
0033958912
-
Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response
-
Nylander K, Bourdon J C, Bray S E et al. Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response. J Pathol 2000: 190: 39-46.
-
(2000)
J Pathol
, vol.190
, pp. 39-46
-
-
Nylander, K.1
Bourdon, J.C.2
Bray, S.E.3
-
29
-
-
0013903520
-
Pyrimidine dimers in ultraviolet-irradiated DNA's
-
Setlow R B, Carrier W L. Pyrimidine dimers in ultraviolet-irradiated DNA's. J Mol Biol 1966: 17: 237-254.
-
(1966)
J Mol Biol
, vol.17
, pp. 237-254
-
-
Setlow, R.B.1
Carrier, W.L.2
-
31
-
-
0032836289
-
DNA photodamage stimulates melanogenesis and other photoprotective responses
-
Gilchrest B A, Eller M S. DNA photodamage stimulates melanogenesis and other photoprotective responses. J Investig Dermatol Symp Proc 1999: 4: 35-40.
-
(1999)
J Investig Dermatol Symp Proc
, vol.4
, pp. 35-40
-
-
Gilchrest, B.A.1
Eller, M.S.2
-
32
-
-
0031711976
-
Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytes
-
Pedeux R, Al-Irani N, Marteau C et.al. Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytes. J Invest Dermatol 1998: 111: 472-477.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 472-477
-
-
Pedeux, R.1
Al-Irani, N.2
Marteau, C.3
-
33
-
-
0030785521
-
Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response
-
Eller M S, Maeda T, Magnoni C, Atwal D, Gilchrest B A. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response. Proc Natl Acad Sci U S A 1997: 94: 12627-12632.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12627-12632
-
-
Eller, M.S.1
Maeda, T.2
Magnoni, C.3
Atwal, D.4
Gilchrest, B.A.5
-
34
-
-
0032996123
-
Enhanced repair of benzo(a)pyrene-induced DNA damage in human cells treated with thymidine dinucleotides
-
Maeda T, Eller M S, Hedayati M, Grossman L, Gilchrest B A. Enhanced repair of benzo(a)pyrene-induced DNA damage in human cells treated with thymidine dinucleotides. Mutat Res 1999: 433: 137-145.
-
(1999)
Mutat Res
, vol.433
, pp. 137-145
-
-
Maeda, T.1
Eller, M.S.2
Hedayati, M.3
Grossman, L.4
Gilchrest, B.A.5
-
35
-
-
0032948110
-
Thymidine dinucleotide mimics the effect of solar simulated irradiation on p53 and p53-regulated proteins
-
Goukassian D A, Eller M S, Yaar M, Gilchrest B A. Thymidine dinucleotide mimics the effect of solar simulated irradiation on p53 and p53-regulated proteins. J Invest Dermatol 1999: 112: 25-31.
-
(1999)
J Invest Dermatol
, vol.112
, pp. 25-31
-
-
Goukassian, D.A.1
Eller, M.S.2
Yaar, M.3
Gilchrest, B.A.4
-
36
-
-
0032822974
-
Age-associated decreases in human DNA repair capacity: Implications for the skin
-
Hadshiew I M, Gilchrest B.A. Age-associated decreases in human DNA repair capacity: Implications for the skin. Age 1999: 22: 45-57.
-
(1999)
Age
, vol.22
, pp. 45-57
-
-
Hadshiew, I.M.1
Gilchrest, B.A.2
-
37
-
-
0008913903
-
Thymidine dinucleotide pre-treatment reduces DNA mutation frequency
-
Khlgatian M, Hadshiew I M, Eller MS, Giese H, Vijg J, Gilchrest B A. Thymidine dinucleotide pre-treatment reduces DNA mutation frequency. J Invest Dermatol 1999: 112: 557A.
-
(1999)
J Invest Dermatol
, vol.112
-
-
Khlgatian, M.1
Hadshiew, I.M.2
Eller, M.S.3
Giese, H.4
Vijg, J.5
Gilchrest, B.A.6
-
38
-
-
6344285987
-
Exposure of fibroblasts to telomere 3′ overhang specific DNA enhances repair of UVB-induced DNA photoproducts and provides protection against UVB-induced mutagenesis
-
Ruenger T, Li G Z, Luo D, Eller M S, Gilchrest B A. Exposure of fibroblasts to telomere 3′ overhang specific DNA enhances repair of UVB-induced DNA photoproducts and provides protection against UVB-induced mutagenesis. J Invest Dermatol 2002: 119: 328A.
-
(2002)
J Invest Dermatol
, vol.119
-
-
Ruenger, T.1
Li, G.Z.2
Luo, D.3
Eller, M.S.4
Gilchrest, B.A.5
-
39
-
-
33845610991
-
T-oligos augment UV-induced protective responses in human skin
-
Arad S, Konnikov N, Goukassian D A, Gilchrest B A. T-oligos augment UV-induced protective responses in human skin. FASEB J 2006: 20: 1895-1897.
-
(2006)
FASEB J
, vol.20
, pp. 1895-1897
-
-
Arad, S.1
Konnikov, N.2
Goukassian, D.A.3
Gilchrest, B.A.4
-
40
-
-
0035185159
-
Stimulation of melanogenesis by DNA oligonucleotides: Effect of size, sequence and 5′ phosphorylation
-
Hadshiew I M, Eller M S, Gasparro F P, Gilchrest B A. Stimulation of melanogenesis by DNA oligonucleotides: Effect of size, sequence and 5′ phosphorylation. J Dermatol Sci 2001: 25: 127-138.
-
(2001)
J Dermatol Sci
, vol.25
, pp. 127-138
-
-
Hadshiew, I.M.1
Eller, M.S.2
Gasparro, F.P.3
Gilchrest, B.A.4
-
41
-
-
0031416522
-
Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene
-
McKay B C, Francis M A, Rainbow A J. Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene. Carcinogenesis 1997: 18: 245-249.
-
(1997)
Carcinogenesis
, vol.18
, pp. 245-249
-
-
McKay, B.C.1
Francis, M.A.2
Rainbow, A.J.3
-
42
-
-
0036352910
-
Induction of apoptosis by telomere 3′ overhang-specific DNA
-
Eller M S, Puri N, Hadshiew I M, Venna S S, Gilchrest B A. Induction of apoptosis by telomere 3′ overhang-specific DNA. Exp Cell Res 2002: 276: 185-193.
-
(2002)
Exp Cell Res
, vol.276
, pp. 185-193
-
-
Eller, M.S.1
Puri, N.2
Hadshiew, I.M.3
Venna, S.S.4
Gilchrest, B.A.5
-
43
-
-
0037309426
-
Induction of a p95/Nbs1-mediated S phase checkpoint by telomere 3′ overhang specific DNA
-
Eller M S, Li G Z, Firoozabadi R, Puri N, Gilchrest B A. Induction of a p95/Nbs1-mediated S phase checkpoint by telomere 3′ overhang specific DNA. FASEB J 2003: 17: 152-162.
-
(2003)
FASEB J
, vol.17
, pp. 152-162
-
-
Eller, M.S.1
Li, G.Z.2
Firoozabadi, R.3
Puri, N.4
Gilchrest, B.A.5
-
44
-
-
8644238845
-
Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides
-
Li G Z, Eller M S, Hanna K, Gilchrest B A. Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides. Exp Cell Res 2004: 301: 189-200.
-
(2004)
Exp Cell Res
, vol.301
, pp. 189-200
-
-
Li, G.Z.1
Eller, M.S.2
Hanna, K.3
Gilchrest, B.A.4
-
45
-
-
33750048144
-
A role for WRN in telomere-based DNA damage responses
-
Eller M S, Liao X, Liu S et.al. A role for WRN in telomere-based DNA damage responses. Proc Natl Acad Sci U S A 2006: 103: 15073-15078.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15073-15078
-
-
Eller, M.S.1
Liao, X.2
Liu, S.3
-
46
-
-
4344650868
-
Telomere-based DNA damage responses: A new approach to melanoma
-
Puri N, Eller M S, Byers H R, Dykstra S, Kubera J, Gilchrest B A. Telomere-based DNA damage responses: A new approach to melanoma. FASEB J 2004: 18: 1373-1381.
-
(2004)
FASEB J
, vol.18
, pp. 1373-1381
-
-
Puri, N.1
Eller, M.S.2
Byers, H.R.3
Dykstra, S.4
Kubera, J.5
Gilchrest, B.A.6
-
47
-
-
33845433298
-
Telomeres rather than telomerase a key target for anti-cancer therapy?
-
Boukamp P, Mirancea N. Telomeres rather than telomerase a key target for anti-cancer therapy? Exp Dermatol 2007: 16: 71-79.
-
(2007)
Exp Dermatol
, vol.16
, pp. 71-79
-
-
Boukamp, P.1
Mirancea, N.2
-
48
-
-
0038701811
-
Telomerase inhibition as cancer therapy
-
Saretzki G. Telomerase inhibition as cancer therapy. Cancer Lett 2003: 194: 209-219.
-
(2003)
Cancer Lett
, vol.194
, pp. 209-219
-
-
Saretzki, G.1
-
49
-
-
33846622360
-
Features that determine telomere homolog oligonucleotide-induced therapeutic DNA damage-like responses in cancer cells
-
Ohashi N, Yaar M, Eller M S, Truzzi F, Gilchrest B A. Features that determine telomere homolog oligonucleotide-induced therapeutic DNA damage-like responses in cancer cells. J Cell Physiol 2007: 210: 582-595.
-
(2007)
J Cell Physiol
, vol.210
, pp. 582-595
-
-
Ohashi, N.1
Yaar, M.2
Eller, M.S.3
Truzzi, F.4
Gilchrest, B.A.5
-
50
-
-
0035018021
-
G-quadruplex DNA structures -variations on a theme
-
Simonsson T. G-quadruplex DNA structures -variations on a theme. Biol Chem 2001: 382: 621-628.
-
(2001)
Biol Chem
, vol.382
, pp. 621-628
-
-
Simonsson, T.1
-
51
-
-
0035900673
-
Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides
-
Xu X, Hamhouyia F, Thomas S D et al. Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides. J Biol Chem 2001: 276: 43221-43230.
-
(2001)
J Biol Chem
, vol.276
, pp. 43221-43230
-
-
Xu, X.1
Hamhouyia, F.2
Thomas, S.D.3
-
52
-
-
0033543548
-
Antiproliferative activity of G-rich oligonucleotides correlates with protein binding
-
Bates P J, Kahlon J B, Thomas S D, Trent J O, Miller D M. Antiproliferative activity of G-rich oligonucleotides correlates with protein binding. J Biol Chem 1999: 274: 26369-26377.
-
(1999)
J Biol Chem
, vol.274
, pp. 26369-26377
-
-
Bates, P.J.1
Kahlon, J.B.2
Thomas, S.D.3
Trent, J.O.4
Miller, D.M.5
-
53
-
-
33846192385
-
G-quadruplexes induce apoptosis in tumor cells
-
Qi H, Lin C P, Fu X et.al. G-quadruplexes induce apoptosis in tumor cells. Cancer Res 2006: 66: 11808-11816.
-
(2006)
Cancer Res
, vol.66
, pp. 11808-11816
-
-
Qi, H.1
Lin, C.P.2
Fu, X.3
-
54
-
-
0033575958
-
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments
-
Saretzki G, Sitte N, Merkel U, Wurm R E, von Zglinicki T. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments. Oncogene 1999: 18: 5148-5158.
-
(1999)
Oncogene
, vol.18
, pp. 5148-5158
-
-
Saretzki, G.1
Sitte, N.2
Merkel, U.3
Wurm, R.E.4
von Zglinicki, T.5
-
55
-
-
34248184169
-
Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells
-
Yaar M, Eller M S, Panova I et.al. Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells. Breast Cancer Res 2007: 9: R13.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Yaar, M.1
Eller, M.S.2
Panova, I.3
-
57
-
-
1642315226
-
Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice
-
Goukassian D A, Helms E, van Steeg H, van Oostrom C, Bhawan J, Gilchrest B A. Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice. Proc Natl Acad Sci U S A 2004: 101: 3933-3938.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3933-3938
-
-
Goukassian, D.A.1
Helms, E.2
van Steeg, H.3
van Oostrom, C.4
Bhawan, J.5
Gilchrest, B.A.6
-
58
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou E P, Pilch D R, Orr A H, Ivanova V S, Bonner W M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998: 273: 5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
59
-
-
33646106590
-
gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
-
Stucki M, Jackson S P. gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair (Amst) 2006: 5: 534-543.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 534-543
-
-
Stucki, M.1
Jackson, S.P.2
-
60
-
-
7244251599
-
Phosphorylation of H2AX at short telomeres in T cells and fibroblasts
-
Hao L Y, Strong M A, Greider C. W. Phosphorylation of H2AX at short telomeres in T cells and fibroblasts. J Biol Chem 2004: 279: 45148-45154.
-
(2004)
J Biol Chem
, vol.279
, pp. 45148-45154
-
-
Hao, L.Y.1
Strong, M.A.2
Greider, C.W.3
-
61
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusions
-
van Steensel B, Smogorzewska A, de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell 1998: 92: 401-413.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
van Steensel, B.1
Smogorzewska, A.2
de Lange, T.3
-
62
-
-
0347362703
-
Werner syndrome protein contains three structure-specific DNA binding domains
-
von Kobbe C, Thoma N H, Czyzewski B K, Pavletich N P, Bohr V A. Werner syndrome protein contains three structure-specific DNA binding domains. J Biol Chem 2003: 278: 52997-53006.
-
(2003)
J Biol Chem
, vol.278
, pp. 52997-53006
-
-
von Kobbe, C.1
Thoma, N.H.2
Czyzewski, B.K.3
Pavletich, N.P.4
Bohr, V.A.5
-
63
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C E, Oshima J, Fu Y H et al. Positional cloning of the Werner's syndrome gene. Science 1996: 272: 258-262.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
-
64
-
-
0014816132
-
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, genotype
-
Martin G M, Sprague C A, Epstein C J. Replicative life-span of cultivated human cells. Effects of donor's age, tissue, genotype. Lab Invest 1970: 23: 86-92.
-
(1970)
Lab Invest
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sprague, C.A.2
Epstein, C.J.3
-
65
-
-
0029971241
-
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
-
Schulz V P, Zakian V A, Ogburn C E et al. Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells. Hum Genet 1996: 97: 750-754.
-
(1996)
Hum Genet
, vol.97
, pp. 750-754
-
-
Schulz, V.P.1
Zakian, V.A.2
Ogburn, C.E.3
-
66
-
-
0942290416
-
TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA
-
Machwe A, Xiao L, Orren D K. TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA. Oncogene 2004: 23: 149-156.
-
(2004)
Oncogene
, vol.23
, pp. 149-156
-
-
Machwe, A.1
Xiao, L.2
Orren, D.K.3
-
67
-
-
2942637828
-
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
-
Opresko P L, Otterlei M, Graakjaer J et al. The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Mol Cell 2004: 14: 763-774.
-
(2004)
Mol Cell
, vol.14
, pp. 763-774
-
-
Opresko, P.L.1
Otterlei, M.2
Graakjaer, J.3
-
68
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
-
Lee J H, Paull T T. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005: 308: 551-554.
-
(2005)
Science
, vol.308
, pp. 551-554
-
-
Lee, J.H.1
Paull, T.T.2
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