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Volumn 8, Issue , 2007, Pages

Identification of sequence motifs significantly associated with antisense activity

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE ACTIVITY; ANTISENSE OLIGONUCLEOTIDES; MODELLING PROCESS; OLIGONUCLEOTIDE SEQUENCES; PREDICTIVE MODELING; RANDOMIZATION PROCEDURE; RNA-INDUCED SILENCING COMPLEXES; SUPPORT VECTOR REGRESSION (SVR);

EID: 34447517391     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-8-184     Document Type: Article
Times cited : (8)

References (24)
  • 1
    • 0032700656 scopus 로고    scopus 로고
    • Molecular mechanisms of action of antisense drugs
    • 10806995
    • Crooke ST Molecular mechanisms of action of antisense drugs Biochim Biophys Acta 1999 1489 1 31-44 10806995
    • (1999) Biochim Biophys Acta , vol.1489 , Issue.1 , pp. 31-44
    • Crooke, S.T.1
  • 2
    • 0031922256 scopus 로고    scopus 로고
    • Molecular mechanisms of antisense drugs: RNase H
    • 9593052
    • Crooke ST Molecular mechanisms of antisense drugs: RNase H Antisense Nucleic Acid Drug Dev 1998 8 2 133-134 9593052
    • (1998) Antisense Nucleic Acid Drug Dev , vol.8 , Issue.2 , pp. 133-134
    • Crooke, S.T.1
  • 3
    • 0036953263 scopus 로고    scopus 로고
    • Computational antisense oligo prediction with a neural network model
    • 10.1093/bioinformatics/18.12.1567 12490440
    • Chalk AM Sonnhammer EL Computational antisense oligo prediction with a neural network model Bioinformatics 2002 18 12 1567-1575 10.1093/ bioinformatics/18.12.1567 12490440
    • (2002) Bioinformatics , vol.18 , Issue.12 , pp. 1567-1575
    • Chalk, A.M.1    Sonnhammer, E.L.2
  • 4
    • 0036800016 scopus 로고    scopus 로고
    • Artificial neural network prediction of antisense oligodeoxynucleotide activity
    • 140555 12364609 10.1093/nar/gkf557
    • Giddings MC Shah AA Freier S Atkins JF Gesteland RF Matveeva OV Artificial neural network prediction of antisense oligodeoxynucleotide activity Nucleic Acids Res 2002 30 19 4295-4304 140555 12364609 10.1093/ nar/gkf557
    • (2002) Nucleic Acids Res , vol.30 , Issue.19 , pp. 4295-4304
    • Giddings, M.C.1    Shah, A.A.2    Freier, S.3    Atkins, J.F.4    Gesteland, R.F.5    Matveeva, O.V.6
  • 5
    • 0035975193 scopus 로고    scopus 로고
    • Rational selection and quantitative evaluation of antisense oligonucleotides
    • 11513951
    • Jayaraman A Walton SP Yarmush ML Roth CM Rational selection and quantitative evaluation of antisense oligonucleotides Biochim Biophys Acta 2001 1520 2 105-114 11513951
    • (2001) Biochim Biophys Acta , vol.1520 , Issue.2 , pp. 105-114
    • Jayaraman, A.1    Walton, S.P.2    Yarmush, M.L.3    Roth, C.M.4
  • 8
    • 0033570886 scopus 로고    scopus 로고
    • A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability
    • 148713 10536139 10.1093/nar/27.22.4328
    • Patzel V Steidl U Kronenwett R Haas R Sczakiel G A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability Nucleic Acids Res 1999 27 22 4328-4334 148713 10536139 10.1093/nar/27.22.4328
    • (1999) Nucleic Acids Res , vol.27 , Issue.22 , pp. 4328-4334
    • Patzel, V.1    Steidl, U.2    Kronenwett, R.3    Haas, R.4    Sczakiel, G.5
  • 9
    • 0034234550 scopus 로고    scopus 로고
    • RNA accessibility prediction: A theoretical approach is consistent with experimental studies in cell extracts
    • 102709 10871393 10.1093/nar/28.13.2455
    • Scherr M Rossi JJ Sczakiel G Patzel V RNA accessibility prediction: A theoretical approach is consistent with experimental studies in cell extracts Nucleic Acids Res 2000 28 13 2455-2461 102709 10871393 10.1093/ nar/28.13.2455
    • (2000) Nucleic Acids Res , vol.28 , Issue.13 , pp. 2455-2461
    • Scherr, M.1    Rossi, J.J.2    Sczakiel, G.3    Patzel, V.4
  • 10
    • 0027289572 scopus 로고
    • Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1
    • 8495105
    • Sczakiel G Homann M Rittner K Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1 Antisense Res Dev 1993 3 1 45-52 8495105
    • (1993) Antisense Res Dev , vol.3 , Issue.1 , pp. 45-52
    • Sczakiel, G.1    Homann, M.2    Rittner, K.3
  • 11
    • 0033860727 scopus 로고    scopus 로고
    • Rational selection of antisense oligonucleotide sequences
    • 10.1016/S0928-0987(00)00100-7 11042224
    • Smith L Andersen KB Hovgaard L Jaroszewski JW Rational selection of antisense oligonucleotide sequences Eur J Pharm Sci 2000 11 3 191-198 10.1016/S0928-0987(00)00100-7 11042224
    • (2000) Eur J Pharm Sci , vol.11 , Issue.3 , pp. 191-198
    • Smith, L.1    Andersen, K.B.2    Hovgaard, L.3    Jaroszewski, J.W.4
  • 12
    • 0033977659 scopus 로고    scopus 로고
    • Application of secondary structure prediction in antisense drug design targeting protein kinase C-alpha mRNA and QSAR analysis
    • 11263253
    • Song HF Tang ZM Yuan SJ Zhu BZ Application of secondary structure prediction in antisense drug design targeting protein kinase C-alpha mRNA and QSAR analysis Acta Pharmacol Sin 2000 21 1 80-86 11263253
    • (2000) Acta Pharmacol Sin , vol.21 , Issue.1 , pp. 80-86
    • Song, H.F.1    Tang, Z.M.2    Yuan, S.J.3    Zhu, B.Z.4
  • 13
    • 0032566621 scopus 로고    scopus 로고
    • Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design
    • 10.1074/jbc.273.39.25125 9737971
    • Tu GC Cao QN Zhou F Israel Y Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design J Biol Chem 1998 273 39 25125-25131 10.1074/jbc.273.39.25125 9737971
    • (1998) J Biol Chem , vol.273 , Issue.39 , pp. 25125-25131
    • Tu, G.C.1    Cao, Q.N.2    Zhou, F.3    Israel, Y.4
  • 14
    • 0033527352 scopus 로고    scopus 로고
    • Prediction of antisense oligonucleotide binding affinity to a structured RNA target
    • 10.1002/(SICI)1097-0290(19991005)65:1<1::AID-BIT1>3.0.CO;2-F 10440665
    • Walton SP Stephanopoulos GN Yarmush ML Roth CM Prediction of antisense oligonucleotide binding affinity to a structured RNA target Biotechnol Bioeng 1999 65 1 1-9 10.1002/ (SICI)1097-0290(19991005)65:1<1::AID-BIT1>3.0.CO;2-F 10440665
    • (1999) Biotechnol Bioeng , vol.65 , Issue.1 , pp. 1-9
    • Walton, S.P.1    Stephanopoulos, G.N.2    Yarmush, M.L.3    Roth, C.M.4
  • 16
    • 0029028723 scopus 로고
    • Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides
    • 307240 7567472 10.1093/nar/23.17.3578
    • Kandimalla ER Manning A Lathan C Byrn RA Agrawal S Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides Nucleic Acids Res 1995 23 17 3578-3584 307240 7567472 10.1093/nar/23.17.3578
    • (1995) Nucleic Acids Res , vol.23 , Issue.17 , pp. 3578-3584
    • Kandimalla, E.R.1    Manning, A.2    Lathan, C.3    Byrn, R.A.4    Agrawal, S.5
  • 17
    • 33645469194 scopus 로고    scopus 로고
    • Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
    • 1421440 16526963 10.1186/1471-2105-7-122
    • Bo X Lou S Sun D Shu W Yang J Wang S Selection of antisense oligonucleotides based on multiple predicted target mRNA structures BMC Bioinformatics 2006 7 122 1421440 16526963 10.1186/1471-2105-7-122
    • (2006) BMC Bioinformatics , vol.7 , pp. 122
    • Bo, X.1    Lou, S.2    Sun, D.3    Shu, W.4    Yang, J.5    Wang, S.6
  • 18
    • 25844435161 scopus 로고    scopus 로고
    • Technical improvements in the computational target search for antisense oligonucleotides
    • 10.1089/oli.2005.15.223 16201910
    • Far RK Leppert J Frank K Sczakiel G Technical improvements in the computational target search for antisense oligonucleotides Oligonucleotides 2005 15 3 223-233 10.1089/oli.2005.15.223 16201910
    • (2005) Oligonucleotides , vol.15 , Issue.3 , pp. 223-233
    • Far, R.K.1    Leppert, J.2    Frank, K.3    Sczakiel, G.4
  • 19
    • 14644417900 scopus 로고    scopus 로고
    • Structural rearrangements in RNA on the binding of an antisense oligonucleotide: Implications for the study of intra-molecular RNA interactions and the design of cooperatively acting antisense reagents with enhanced efficacy
    • 10.1080/10611860400003825 15848955
    • Sohail M Doran G Kang S Akhtar S Southern EM Structural rearrangements in RNA on the binding of an antisense oligonucleotide: Implications for the study of intra-molecular RNA interactions and the design of cooperatively acting antisense reagents with enhanced efficacy J Drug Target 2005 13 1 61-70 10.1080/10611860400003825 15848955
    • (2005) J Drug Target , vol.13 , Issue.1 , pp. 61-70
    • Sohail, M.1    Doran, G.2    Kang, S.3    Akhtar, S.4    Southern, E.M.5
  • 20
    • 0033665573 scopus 로고    scopus 로고
    • ODNBase--a web database for antisense oligonucleotide effectiveness studies. Oligodeoxynucleotides
    • 10.1093/bioinformatics/16.9.843 11108708
    • Giddings MC Matveeva OV Atkins JF Gesteland RF ODNBase--a web database for antisense oligonucleotide effectiveness studies. Oligodeoxynucleotides Bioinformatics 2000 16 9 843-844 10.1093/ bioinformatics/16.9.843 11108708
    • (2000) Bioinformatics , vol.16 , Issue.9 , pp. 843-844
    • Giddings, M.C.1    Matveeva, O.V.2    Atkins, J.F.3    Gesteland, R.F.4
  • 21
    • 84886765629 scopus 로고    scopus 로고
    • United States Patent Office http://www.uspto.gov
  • 22
    • 84874656820 scopus 로고    scopus 로고
    • IDT ftp repository ftp://scitoolsftp.idtdna.com
    • IDT ftp repository ftp://scitoolsftp.idtdna.com
  • 24
    • 0032539693 scopus 로고    scopus 로고
    • A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
    • 19045 9465037 10.1073/pnas.95.4.1460
    • SantaLucia J Jr. A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics Proc Natl Acad Sci U S A 1998 95 4 1460-1465 19045 9465037 10.1073/pnas.95.4.1460
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.4 , pp. 1460-1465
    • SantaLucia Jr., J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.