Paradoxical expression of maspin in gastric carcinomas: correlation with carcinogenesis and progression

Human Pathology

Volumn 38, Issue 8, 2007, Pages 1248-1255

  Yu, Miao ^a   Zheng, Huachuan ^a   Tsuneyama, Koichi ^a   Takahashi, Hiroyuki ^a   Nomoto, Kazuhiro ^a   Xu, Huimian ^a   Takano, Yasuo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Carcinogenesis; Gastric carcinoma; Maspin

Indexed keywords

MASPIN;

ADENOMA; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CARCINOMA; STOMACH MUCOSA; TISSUE MICROARRAY; UPREGULATION; WESTERN BLOTTING;

ADENOCARCINOMA; ADENOMA; ADULT; AGED; AGED, 80 AND OVER; CELL NUCLEUS; CYTOPLASM; DISEASE PROGRESSION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; HUMANS; LYMPH NODES; MALE; METAPLASIA; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PRECANCEROUS CONDITIONS; SERPINS; STOMACH; STOMACH NEOPLASMS; SURVIVAL RATE; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 34447318352     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.11.025     Document Type: Article

References (34)

1. Zou Z., Anisowicz A., Hendrix M.J., et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 263 (1994) 526-529
2. Schneider S.S., Schick C., Fish K.E., et al. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A 92 (1995) 3147-3151
3. Maass N., Hojo T., Zhang M., Sager R., Jonat W., and Nagasaki K. Maspin-a novel protease inhibitor with tumor-suppressing activity in breast cancer. Acta Oncol 39 (2000) 931-934
4. Zhang W., Shi H.Y., and Zhang M. Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins. BMC Cancer 5 (2005) 50
5. Liu J., Yin S., Reddy N., Spencer C., and Sheng S. Bax mediates the apoptosis-sensitizing effect of maspin. Cancer Res 64 (2004) 1703-1711
6. Zhang M., Volpert O., Shi Y.H., and Bouck N. Maspin is an angiogenesis inhibitor. Nat Med 6 (2000) 196-199
7. Zhang M., Sheng S., Maass N., and Sager R. mMaspin: the mouse homolog of a human tumor suppressor gene inhibits mammary tumor invasion and motility. Mol Med 3 (1997) 49-59
8. Zheng H.C., Wang M.C., Li J.Y., Yang X.F., Sun J.M., and Xin Y. Expression of maspin and kai1 and their clinicopathological significance in carcinogenesis and progression of gastric cancer. Chin Med Sci J 19 (2004) 193-198
9. Maass N., Hojo T., Ueding M., et al. Expression of the tumor suppressor gene maspin in human pancreatic cancers. Clin Cancer Res 7 (2001) 812-817
10. Sood A.K., Fletcher M.S., Gruman L.M., et al. The paradoxical expression of maspin in ovarian carcinoma. Clin Cancer Res 8 (2002) 2924-2932
11. Marioni G., Blandamura S., Giacomelli L., et al. Nuclear expression of maspin is associated with a lower recurrence rate and a longer disease-free interval after surgery for squamous cell carcinoma of the larynx. Histopathology 46 (2005) 576-582
12. Mohsin S.K., Zhang M., Clark G.M., and Craig Allred D. Maspin expression in invasive breast cancer: association with other prognostic factors. J Pathol 199 (2003) 432-435
13. Akiyama Y., Maesawa C., Ogasawara S., Terashima M., and Masuda T. Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells. Am J Pathol 163 (2003) 1911-1919
14. Bettstetter M., Woenckhaus M., Wild P.J., et al. Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer. J Pathol 205 (2005) 606-614
15. Kelley J.R., and Duggan J.M. Gastric cancer epidemiology and risk factors. J Clin Epidemiol 56 (2003) 1-9
16. Son H.J., Sohn T.S., Song S.Y., Lee J.H., and Rhee J.C. Maspin expression in human gastric adenocarcinoma. Pathol Int 52 (2002) 508-513
17. Ito R., Nakayama H., Yoshida K., Oda N., and Yasui W. Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality. Oncol Rep 12 (2004) 985-990
18. Sobin L.H., and Wittekind C.H. TNM classification of malignant tumors. 6th ed. (2002), John Wiley & Sons, Hoboken (NJ)
19. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64 (1965) 31-49
20. Kumada T., Tsuneyama K., Hatta H., Ishizawa S., and Takano Y. Improved 1-h rapid immunostaining method using intermittent microwave irradiation: practicability based on 5 years application in Toyama Medical and Pharmaceutical University Hospital. Mod Pathol 17 (2004) 1141-1149
21. Harlozinska A. Progress in molecular mechanisms of tumor metastasis and angiogenesis. Anticancer Res 25 (2005) 3327-3333
22. Chen E.I., Florens L., Axelrod F.T., et al. Maspin alters the carcinoma proteome. FASEB J 19 (2005) 1123-1124
23. Kim S., Han J., Kim J., and Park C. Maspin expression is transactivated by p63 and is critical for the modulation of lung cancer progression. Cancer Res 64 (2004) 6900-6905
24. Lonardo F., Li X., Siddiq F., et al. Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma. Lung Cancer 51 (2006) 31-39
25. Maass N., Hojo T., Rosel F., Ikeda T., Jonat W., and Nagasaki K. Down regulation of the tumor suppressor gene maspin in breast carcinoma is associated with a higher risk of distant metastasis. Clin Biochem 34 (2001) 303-307
26. Beecken W.D., Engl T., Engels K., et al. Clinical relevance of maspin expression in bladder cancer. World J Urol 24 (2006) 338-344
27. Boltze C. Loss of maspin is a helpful prognosticator in colorectal cancer: a tissue microarray analysis. Pathol Res Pract 200 (2005) 783-790
28. Chen E.I., and Yates J.R. Maspin and tumor metastasis. IUBMB Life 58 (2006) 25-29
29. Terashima M., Maesawa C., Oyama K., et al. Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis. Br J Cancer 92 (2005) 1130-1136
30. Song S.Y., Lee S.K., Kim D.H., et al. Expression of maspin in colon cancers: its relationship with p53 expression and microvessel density. Dig Dis Sci 47 (2002) 1831-1835
31. Xu C., Quddus M.R., Sung C.J., Steinhoff M.M., Zhang C., and Lawrence W.D. Maspin expression in CIN 3, microinvasive squamous cell carcinoma, and invasive squamous cell carcinoma of the uterine cervix. Mod Pathol 18 (2005) 1102-1106
32. Machtens S., Serth J., Bokemeyer C., et al. Expression of the p53 and Maspin protein in primary prostate cancer: correlation with clinical features. Int J Cancer 95 (2001) 337-342
33. Umekita Y., and Yoshida H. Expression of maspin is up-regulated during the progression of mammary ductal carcinoma. Histopathology 42 (2003) 541-545
34. Hirai K., Koizumi K., Haraguchi S., et al. Prognostic significance of the tumor suppressor gene maspin in non-small cell lung cancer. Ann Thorac Surg 79 (2005) 248-253