Expression of maspin is up-regulated during the progression of mammary ductal carcinoma

Histopathology

Volumn 42, Issue 6, 2003, Pages 541-545

  Umekita, Yoshihisa ^a   Yoshida, H ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Ductal carcinoma in situ; Immunohistochemistry; Maspin

Indexed keywords

MASPIN;

ARTICLE; CANCER GRADING; CARCINOMA IN SITU; COMEDO NECROSIS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; MASPIN GENE; PRIORITY JOURNAL; TISSUE NECROSIS; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DISEASE PROGRESSION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODES; LYMPHATIC METASTASIS; PROTEINS; SERPINS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 0037832784     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.2003.01620.x     Document Type: Article

References (21)

1. Zou Z, Anisowicz A, Hendrix MJ et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 1994; 263; 526-529.
2. Sheng S, Pemberton P, Sagar R. Production, purification and characterization of recombinant maspin protein. J. Biol. Chem. 1994: 269; 30988-30993.
3. Sheng S, Carey J, Seftor EA et al. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl Acad. Sci. USA 1996; 93; 11669-11674.
4. Sheng S, Truong B, Fredrickson D et al. Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin. Proc. Natl Acad. Sci. USA 1998; 95; 499-504.
5. Maass N, Teffner M, Rosel F et al. Decline in the expression of the serine proteinase inhibitor maspin is associated with tumor progression in ductal carcinoma of the breast. J. Pathol. 2001; 195; 321-326.
6. Umekita Y, Ohi Y, Sagara Y et al. Expression of maspin predicts poor prognosis in breast-cancer patients. Int. J. Cancer 2002; 100; 452-455.
7. Silverstein MJ, Poller DN, Waisman JR et al. Prognostic classification of breast ductal carcinoma-in-situ. Lancet 1995; 345; 1154-1157.
8. World Health Organization. Histological typing of breast tumours. 2nd edn. Geneva: WHO. 1981.
9. UICC International Union Against Cancer. Breast tumours. In Sobin LH, Wittekind C eds. TNM classification of malignant tumours. 5th edn. New York: Wiley-Liss. 1997; 123-130.
10. Umekita Y, Takasaki T, Yoshida H. Expression of p53 protein in benign epithelial hyperplasia, atypical ductal hyperplasia, noninvasive and invasive mammary carcinoma: an immunohistochemical study. Virchows Arch. 1994; 424; 491-494.
11. Page DL, Rogers LW. Combined histologic and cytologic criteria for the diagnosis of mammary atypical ductal hyperplasia. Hum. Pathol. 1992; 23; 1095-1097.
12. Umekita Y, Hiipakka RA, Liao S. Rat and human maspins: structures, metastatic suppressor activity and mutation in prostate cancer cells. Cancer Lett. 1997; 113; 87-93.
13. Umekita Y, Hiipakka RA, Kokontis JM et al. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride. Proc. Natl Acad. Sci. USA 1996; 93; 11802-11807.
14. Hendricks JB, Wilkinson EJ. Comparison of two antibodies for evaluation of estrogen receptors in paraffin-embedded tumors. Mod. Pathol. 1993; 6; 765-770.
15. Maass N, Hojo T, Rosel F et al. Down regulation of the tumor suppressor gene maspin in breast carcinoma is associated with a higher risk of distant metastasis. Clin. Biochem. 2001: 34; 303-307.
16. Sternlichit MD, Kedeshian P, Shao ZM et al. The human myoepithelial cell is a natural tumor suppressor. Clin. Cancer Res. 1997; 3; 1949-1958.
17. Ballestrero A, Coviello DA, Garuti A et al. Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. Cancer 2001: 92; 2030-2035.
18. Liu T, Pemberton PA, Robertson AD. Three-state unfolding and self association of maspin, a tumor-suppressing serpin. J. Biol. Chem. 1999: 274; 29628-29632.
19. Jones C, Nonni AV, Fuitord L et al. CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. Br. J. Cancer 2001: 85; 422-427.
20. Maass N, Hojo T, Ueding M et al. Expression of the tumor suppressor gene Maspin in human pancreatic cancers. Clin. Cancer Res. 2001: 7; 812-817.
21. Sood AK, Fletcher MS, Gruman LM et al. The paradoxical expression of maspin in ovarian carcinoma. Clin. Cancer Res. 2002; 8; 2924-2932.