Pharmacokinetics of letrozole in male and female rats: Influence of complexation with hydroxybutenyl-β-cyclodextrin

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 6, 2007, Pages 795-802

  Wempe, Michael F ^a,b   Buchanan, Charles M ^a   Buchanan, Norma L ^a   Edgar, Kevin J ^a   Hanley, Gregory A ^b   Ramsey, Michael G ^a   Skotty, Jennifer S ^a   Rice, Peter J ^b  

^a EASTMAN CHEMICAL COMPANY   (United States)

^b EAST TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLODEXTRIN DERIVATIVE; HYDROXYBUTENYL BETA CYCLODEXTRIN; LETROZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BREAST CANCER; COMPLEX FORMATION; CONTROLLED STUDY; DISSOLUTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; RAT; SEX DIFFERENCE;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CAPSULES; CHEMISTRY, PHARMACEUTICAL; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; NITRILES; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; SOLUBILITY; TRIAZOLES;

EID: 34447316997     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.6.0006     Document Type: Article

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