Gender difference in letrozole pharmacokinetics in rats

Acta Pharmacologica Sinica

Volumn 21, Issue 8, 2000, Pages 680-684

  Lui, X D ^a   Lin, X ^a   Zhong, Y ^a   Li, C X ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Gender difference; Letrozole; Pharmacokinetics

Indexed keywords

LETROZOLE;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; ESTROGEN SYNTHESIS; GENDER IDENTITY; NONHUMAN; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; AROMATASE; AROMATASE INHIBITORS; ENZYME INHIBITORS; FEMALE; MALE; NITRILES; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; TISSUE DISTRIBUTION; TRIAZOLES;

EID: 0033870663     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Comprehensive pharmacology and clinical efficacy of aromatase inhibitors
2. Letrozole: A review of its use in postmenopausal women with advanced breast cancer
3. High-performance liquid chromatography of the aromatase inhibitor, letrozole, and its metabolite in biological fluids with automated liquid-solid extraction and fluorescence detection
4. Development, apllication and comparison of an enzyme immunoassay and a high-performance liquid chromatography method for the determination of the aromatase inhibitor CGS 20267 in biological fluids
5. Gender as a factor for adverse events to medication
6. Gender differences in toxicokinetics, liver metabolism, and plasma esterase activity: Observations from a chronic (27-weeks) toxixity study of enalapril/diltiazem combinations in rats
7. The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin
8. Effect of age and gender on tirialzad pharmacokine tics in humans