Solid-phase synthesis of a combinatorial array of 1,3-bis(acylamino)-2-butanones, inhibitors of the cysteine proteases cathepsins K and L

Journal of Combinatorial Chemistry

Volumn 1, Issue 3, 1999, Pages 207-215

  Yamashita, Dennis S ^a   Dong, Xiaoyang ^a   Oh, Hye Ja ^a   Brook, Christopher S ^a   Tomaszek, Thaddeus A ^a   Szewczuk, Lawrence ^a   Tew, David G ^a   Veber, Daniel F ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BIS(ACYLAMINO) 2 BUTANONE; 1,3-BIS(ACYLAMINO)-2-BUTANONE; ALKANONE; CATHEPSIN; CATHEPSIN K; CATHEPSIN L; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; PROTEINASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; KINETICS; METHODOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BUTANONES; CATHEPSINS; COMBINATORIAL CHEMISTRY TECHNIQUES; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; ENDOPEPTIDASES; KINETICS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033123142     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc9800374     Document Type: Article

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