Cellular lifespan and regenerative medicine

Biomaterials

Volumn 28, Issue 26, 2007, Pages 3751-3756

  Petersen, Thomas ^a,b   Niklason, Laura ^b  

^a Duke University   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

ALT; bcl 2; Cellular lifespan; Telomerase

Indexed keywords

ALT; B-CELL LYMPHOMA 2 (BCL-2) EXPRESSION; CELL POPULATIONS; CELLULAR LIFESPAN; TELOMERAS;

CELLS; DRUG PRODUCTS; ENZYME ACTIVITY; TISSUE ENGINEERING;

PATIENT TREATMENT;

PROTEIN BCL 2; TELOMERASE REVERSE TRANSCRIPTASE;

ARTICLE; B CELL LYMPHOMA; CARCINOGENESIS; CELL DIFFERENTIATION; CELL DIVISION; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGENERATIVE MEDICINE; STEM CELL; TISSUE ENGINEERING;

CELL CULTURE TECHNIQUES; CELL SURVIVAL; HUMANS; PRESERVATION, BIOLOGICAL; REGENERATIVE MEDICINE; STEM CELLS; TISSUE ENGINEERING;

EID: 34447268986     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.05.012     Document Type: Article

References (52)

1. Poh M., Boyer M., Solan S., Dahl S.L.M., Pedrotty D., Banik S.S., et al. Blood vessels engineered from human cells. Lancet 365 (2005) 2122-2124
2. Peterson B., Zhang J., Iglesias R., Kabo M., Hedrick M., Benhaim P., et al. Healing of critically sized femoral defects, using genetically modified mesenchymal stem cells from human adipose tissue. Tissue Eng 11 (2005) 120-129
3. Ohashi K., Waugh J.M., Dake M.D., Yokohama T., Kuge H., Nakajima Y., et al. Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver disease. Hepatology 41 (2005) 132-140
4. Swift M.E., Kleinman H.K., and DiPietro L.A. Impaired wound repair and delayed angiogenesis in aged mice. Lab Invest 79 (1999) 1479-1487
5. Minamino T., Miyauchi H., Yoshida T., Tateno K., Kunieda T., and Komura I. Vascular cell senescence and vascular aging. J Mol Cell Cardiol 36 (2004) 175-183
6. Rao M.S., and Reddy J.K. Pancreatic stem cells: differentiation options. Stem Cell Rev 1 (2005) 265-272
7. Schechner J.S., Nath A.K., Zheng L., Kluger M.S., Hughes C.C.W., Sierra-Honigmann M.R., et al. In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse. PNAS 97 (2000) 9191-9196
8. Bodnar A.G., Ouellette M., Frolkis M., Holt S.E., Chiu C.-P., Morin G.B., et al. Extension of lifespan by introduction of telomerase into normal human cells. Science 279 (1998) 349-352
9. Yang J., Chang E., Cherry A.M., Bangs C.D., Oei Y., Bodnar A., et al. Human endothelial cell life extension by telomerase expression. J Biol Chem 274 (1999) 26141-26148
10. Simonsen J.L., Rosada C., Serakinci N., Justesen J., Stenderup K., Rattan S.I.S., et al. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotech 20 (2002) 592-596
11. Shay J.W., and Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 33 (1997) 787-791
12. Lee K.-D., Kuo T.K.-C., Whang-Peng J., Chung Y.-F., Lin C.-T., Chou S.-H., et al. In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology 40 (2004) 1275-1284
13. Petite H., Viateau V., Bensaid W., Meunier A., de Pollak C., Bourguignon M., et al. Tissue-engineered bone regeneration. Nat Biotechnol 18 (2000) 959-963
14. Jackson K.A., Majka S.M., Wang H., Pocius J., Hartley C., Majesky M., et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 107 (2001) 1395-1402
15. Schmidt D., Asmis L.M., Odermatt B., Kelm J., Breymann C., Gossi M., et al. Engineered living blood vessels: functional endothelia generated from human umbilical cord-derived precursors. Ann Thorac Surg 82 (2006) 1465-1471
16. Shepherd B.R., Enis D.R., Wang F., Suarez Y., Pober J.S., and Schechner J.S. Vascularization and engraftment of a human skin subsitute using circulating progenitor cell-derived endothelial cells. FASEB J 20 (2006) E1124-E1132
17. Bianco P., and Robey P.G. Stem cells in tissue engineering. Nature 414 (2001) 118-121
18. Levenberg S., Golub J.S., Amit M., Itskovitz-Eldor J., and Langer R. Endothelial cells derived from human embryonic stem cells. PNAS 99 (2002) 4391-4396
19. n, present at the telomeres of human chromosomes. Proc Natl Acad Sci 85 (1988) 6622-6626
20. Hayflick L., and Moorehead P.S. The serial cultivation of human diploid cell strains. Exp Cell Res 25 (1961) 585-621
21. Harley C.B., Vaziri H., Counter C.M., and Allsopp R.C. The telomere hypothesis of cellular aging. Exp Gerontol 27 (1992) 375-382
22. Counter C.M., Press W., and Compton C.C. Telomere shortening in cultured autografts of patients with burns. Lancet 361 (2003) 1345-1346
23. Kolquist K.A., Ellisen L.W., Counter C.M., Meyerson M., Tan L.K., Weinberg R.A., et al. Expression of hTERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet 19 (1998) 182-186
24. Jiang X.R., Jimenez G., Chang E., Frolkis M., Kusler B., Sage M., et al. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 21 (1999) 111-114
25. Klinger R.Y., Blum J.L., Hearn B., Lebow B., and Niklason L.E. Relevance and safety of telomerase for human tissue engineering. PNAS 103 (2006) 2500-2505
26. Veitonmaki N., Fuxe J., Hultdin M., Roos G., Pettersson R.F., and Cao Y. Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16-INK4A/pRB. FASEB J 17 (2003) 764-766
27. Palanca-Wessels M.C.A., Klingelhutz A., Reid B.J., Norwood T.H., Opheim K.E., Paulson T.G., et al. Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. Carcinogenesis 24 (2003) 1183-1190
28. Roth A., Baerlocher G.M., Schertzer M., Chavez E., Duhrsen U., and Lansdorp P.M. Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT. Blood 106 (2005) 43-50
29. Wang J., Hannon G.J., and Beach D.H. Risky immortalization by telomerase. Nature 405 (2000) 755-756
30. Kiyono T., Foster S.A., Koop J.I., McDougall J.K., Galloway D.A., and Klingelhutz A.J. Both Rb/p16-INK4A inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396 (1998) 84-88
31. Harley C.B. Telomerase is not an oncogene. Oncogene 21 (2002) 494-502
32. Ungrin M.D., and Harrington L. Strict control of telomerase activation using Cre-mediated inversion. BMC Biotechnol 6 (2006) 10-19
33. Rudolph K.L., Chang S., Millard M., Schreiber-Agus N., and DePinho R.A. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science 287 (2000) 1253-1258
34. Colgin L.M., Baran K., Baumann P., Cech T.R., and Reddel R.R. Human POT1 facilitates telomere elongation by telomerase. Curr Biol 13 (2003) 942-946
35. Wang S., Rosengren L.E., Hamberger A., and Haglid K.G. Antisense inhibition of BCL-2 expressoin induces retinoic acid-mediated cell death during differentiation of human NT2N neurons. J Neurochem 76 (2001) 1089-1098
36. Tran V.V., Chen G., Newgard C.B., and Hohmeier H.E. Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy. Diabetes 52 (2003) 1423-1432
37. Tey B.T., Singh R.P., Piredda L., Piacentini M., and Al-Rubeai M. Influence of Bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody. Biotech Bioeng 68 (2000) 31-43
38. Kutschka I., Kofidis T., Chen I.Y., von Degenfeld G., Zwierzchoniewska M., Hoyt G., et al. Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts. Circulation 114 (2006) I-174-80
39. Enis D.R., Shepherd B.R., Wang Y., Qasim A., Shanahan C.M., Weissberg P.L., et al. Induction, differentiation and remodeling of blood vessels after transplantation of Bcl-2-transduced endothelial cells. PNAS 102 (2005) 425-430
40. Lin T.-M., Tsai J.-L., Lin S.-D., Lai C.-S., and Chang C.-C. Accelerated growth and prolonged lifespan of adipose tissue-derived human mesenchymal stem cells in a medium using reduced calcium and antioxidants. Stem Cells Dev 14 (2005) 92-102
41. Lehle K., Hoenicka N., Jacobs V.R., Schmid F.X., and Birnbaum D.E. Identification and reduction of cryoinjury in endothelial cells: a first step toward establishing a cell bank for vascular tissue engineering. Tissue Eng 12 (2006) 3439-3447
42. Fujita R., Hui T., Chelly M., and Demetriou A.A. The effect of antioxidants and a caspase inhibitor on cryopreserved rat hepatocytes. Cell Transplant 14 (2005) 391-396
43. Stewart S.A. Telomere maintenance and tumorigenesis: an alternative road. Curr Mol Med 5 (2005) 253-257
44. Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., and Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3 (1997) 1271-1274
45. Wang R.C., Smogorzewska A., and de Lange T. Homologous recombination generates T-loop-sized deletions at human telomeres. Cell 119 (2004) 355-368
46. Dunham M.A., Neumann A.A., Fasching C.L., and Reddel R.R. Telomere lengthening by recombination in human cells. Nat Genet 26 (2000) 447-450
47. Henson J.D., Neuman A.A., Yeager T.R., and Reddel R.R. Alternative lengthening of telomeres in mammalian cells. Oncogene 21 (2002) 598-610
48. Mitchell J.R., Wood E., and Collins K. A telomerase component is defective in the human disease dyskeratosis congenital. Nature 402 (1999) 551-555
49. Mason P.J., Wilson D.B., and Bessler M. Dyskeratosis congenital-a disease of dysfunctional telomere maintenance. Curr Mol Med (2005) 5159-5170
50. Blasco M.A., Lee H.W., Hande M.P., Samper E., Lansdorp P.M., DePinho R.A., et al. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91 (1997) 25-34
51. Grounds M.D. Muscle regeneration: molecular aspects and therapeutic implications. Curr Opin Neurol 12 (1999) 535-543
52. Seigneurin-Venin S., Bernard V., and Tremblay J.P. Telomerase allows the immortalization of T antigen-positive DMD myoblasts: a new source of cells for gene transfer application. Gene Ther 7 (2000) 619-623