-
1
-
-
0030987070
-
Regulation of protein kinase C
-
Newton, A. C. (1997) Regulation of protein kinase C. Curr. Opin. Cell Biol. 9, 161-167
-
(1997)
Curr. Opin. Cell Biol
, vol.9
, pp. 161-167
-
-
Newton, A.C.1
-
2
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Nishizuka, Y. (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
3
-
-
0021879854
-
Interleukin-2 stimulates association of protein kinase C with plasma membrane
-
Farrar, W. L. and Anderson, W. B. (1985) Interleukin-2 stimulates association of protein kinase C with plasma membrane. Nature 315, 233-235
-
(1985)
Nature
, vol.315
, pp. 233-235
-
-
Farrar, W.L.1
Anderson, W.B.2
-
4
-
-
0032582525
-
Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals
-
Oancea, E. and Meyer, T. (1998) Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals. Cell 95, 307-318
-
(1998)
Cell
, vol.95
, pp. 307-318
-
-
Oancea, E.1
Meyer, T.2
-
5
-
-
0031466995
-
Direct visualization of the translocation of the γ-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein
-
Sakai, N., Sasaki, K., Ikegaki, N., Shirai, Y., Ono, Y. and Saito, N. (1997) Direct visualization of the translocation of the γ-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein. J. Cell Biol. 139, 1465-1476
-
(1997)
J. Cell Biol
, vol.139
, pp. 1465-1476
-
-
Sakai, N.1
Sasaki, K.2
Ikegaki, N.3
Shirai, Y.4
Ono, Y.5
Saito, N.6
-
6
-
-
0031865214
-
Three distinct mechanisms for translocation and activation of the δ subspecies of protein kinase C
-
Ohmori, S., Shirai, Y., Sakai, N., Fujii, M., Konishi, H., Kikkawa, U. and Saito, N. (1998) Three distinct mechanisms for translocation and activation of the δ subspecies of protein kinase C. Mol. Cell. Biol. 18, 5263-5271
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 5263-5271
-
-
Ohmori, S.1
Shirai, Y.2
Sakai, N.3
Fujii, M.4
Konishi, H.5
Kikkawa, U.6
Saito, N.7
-
7
-
-
0037124093
-
Importance of C1B domain for lipid messenger-induced targeting of protein kinase
-
Kashiwagi, K., Shirai, Y., Kuriyama, M., Sakai, N. and Saito, N. (2002) Importance of C1B domain for lipid messenger-induced targeting of protein kinase C. J. Biol. Chem. 277, 18037-18045
-
(2002)
C. J. Biol. Chem
, vol.277
, pp. 18037-18045
-
-
Kashiwagi, K.1
Shirai, Y.2
Kuriyama, M.3
Sakai, N.4
Saito, N.5
-
8
-
-
0037462741
-
Mechanisms of regulation of phospholipase D1 by protein kinase Cα
-
Hu, T. and Exton, J. H. (2003) Mechanisms of regulation of phospholipase D1 by protein kinase Cα. J. Biol. Chem. 278, 2348-2355
-
(2003)
J. Biol. Chem
, vol.278
, pp. 2348-2355
-
-
Hu, T.1
Exton, J.H.2
-
9
-
-
0037636466
-
The regulatory domain of protein kinase Cθ localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells
-
Schultz, A., Jönsson, J.-I. and Larsson, C. (2003) The regulatory domain of protein kinase Cθ localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells. Cell Death Differ. 10, 662-675
-
(2003)
Cell Death Differ
, vol.10
, pp. 662-675
-
-
Schultz, A.1
Jönsson, J.-I.2
Larsson, C.3
-
10
-
-
0033577576
-
PKCε, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells
-
Zeidman, R., Löfgren, B., Påhlman, S. and Larsson, C. (1999) PKCε, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells. J. Cell Biol. 145, 713-726
-
(1999)
J. Cell Biol
, vol.145
, pp. 713-726
-
-
Zeidman, R.1
Löfgren, B.2
Påhlman, S.3
Larsson, C.4
-
11
-
-
0037200009
-
Induction of apoptosis by protein kinase Cδ is independent of its kinase activity
-
Goerke, A., Sakai, N., Gutjahr, E., Schlapkohl, W. A., Mushinski, J. F., Haller, H., Kolch, W., Saito, N. and Mischak, H. (2002) Induction of apoptosis by protein kinase Cδ is independent of its kinase activity. J. Biol. Chem. 277, 32054-32062
-
(2002)
J. Biol. Chem
, vol.277
, pp. 32054-32062
-
-
Goerke, A.1
Sakai, N.2
Gutjahr, E.3
Schlapkohl, W.A.4
Mushinski, J.F.5
Haller, H.6
Kolch, W.7
Saito, N.8
Mischak, H.9
-
12
-
-
0026548701
-
Kinetic analysis of protein kinase C inhibition by staurosporine: Evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates
-
Ward, N. E. and O'Brian, C. A. (1992) Kinetic analysis of protein kinase C inhibition by staurosporine: evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates. Mol. Pharmacol. 41, 387-392
-
(1992)
Mol. Pharmacol
, vol.41
, pp. 387-392
-
-
Ward, N.E.1
O'Brian, C.A.2
-
13
-
-
0025942516
-
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase
-
Toullec, D., Pianetti, P., Coste, H., Bellevergue, P., Grand-Perret, T., Ajakane, M., Baudet, V., Boissin, P., Boursier, E., Loriolle, F., Duhamel, L. et al. (1991) The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266, 15771-15781
-
(1991)
C. J. Biol. Chem
, vol.266
, pp. 15771-15781
-
-
Toullec, D.1
Pianetti, P.2
Coste, H.3
Bellevergue, P.4
Grand-Perret, T.5
Ajakane, M.6
Baudet, V.7
Boissin, P.8
Boursier, E.9
Loriolle, F.10
Duhamel, L.11
-
14
-
-
0026538078
-
Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity
-
Davis, P. D., Elliott, L. H., Harris, W., Hill, C. H., Hurst, S. A., Keech, E., Kumar, M. K., Lawton, G. and Nixon J.S., Wilkinson S. E. (1992) Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity. J. Med. Chem. 35, 994-1001.
-
(1992)
J. Med. Chem
, vol.35
, pp. 994-1001
-
-
Davis, P.D.1
Elliott, L.H.2
Harris, W.3
Hill, C.H.4
Hurst, S.A.5
Keech, E.6
Kumar, M.K.7
Lawton, G.8
Nixon, J.S.9
Wilkinson, S.E.10
-
15
-
-
0027157640
-
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976
-
Martiny-Baron, G., Kazanietz, M. G., Mischak, H., Blumberg, P. M., Kochs, G., Hug, H., Marmé, D. and Schächtele, C. (1993) Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268, 9194-9197
-
(1993)
J. Biol. Chem
, vol.268
, pp. 9194-9197
-
-
Martiny-Baron, G.1
Kazanietz, M.G.2
Mischak, H.3
Blumberg, P.M.4
Kochs, G.5
Hug, H.6
Marmé, D.7
Schächtele, C.8
-
16
-
-
9644264028
-
Catalytic domain crystal structure of protein kinase C-θ (PKCθ)
-
Xu, Z.-B., Chaudhary, D., Olland, S., Wolfram, S., Czerwinski, R., Malakian, K., Lin, L., Stahl, M. L., Joseph-McCarthy, D., Benander, C., Fitz, L., Greco, R. et al. (2004) Catalytic domain crystal structure of protein kinase C-θ (PKCθ). J. Biol. Chem. 279, 50401-50409
-
(2004)
J. Biol. Chem
, vol.279
, pp. 50401-50409
-
-
Xu, Z.-B.1
Chaudhary, D.2
Olland, S.3
Wolfram, S.4
Czerwinski, R.5
Malakian, K.6
Lin, L.7
Stahl, M.L.8
Joseph-McCarthy, D.9
Benander, C.10
Fitz, L.11
Greco, R.12
-
17
-
-
24644488646
-
Crystal structure of the catalytic domain of human atypical protein kinase C-ι reveals interaction mode of phosphorylation site in turn motif
-
Messerschmidt, A., Madeira, S., Velarde, M., Badeker, M., Benda, C., Jestel, A., Brandstetter, H., Neuefeind, T. and Blaesse, M. (2005) Crystal structure of the catalytic domain of human atypical protein kinase C-ι reveals interaction mode of phosphorylation site in turn motif. J. Mol. Biol. 352, 918-931
-
(2005)
J. Mol. Biol
, vol.352
, pp. 918-931
-
-
Messerschmidt, A.1
Madeira, S.2
Velarde, M.3
Badeker, M.4
Benda, C.5
Jestel, A.6
Brandstetter, H.7
Neuefeind, T.8
Blaesse, M.9
-
18
-
-
4644326204
-
Autophosphorylation suppresses whereas kinase inhibition augments the translocation of protein kinase Cα in response to diacylglycerol
-
Stensman, H., Rraghunath, A. and Larsson, C. (2004) Autophosphorylation suppresses whereas kinase inhibition augments the translocation of protein kinase Cα in response to diacylglycerol. J. Biol. Chem. 279, 40576-40583
-
(2004)
J. Biol. Chem
, vol.279
, pp. 40576-40583
-
-
Stensman, H.1
Rraghunath, A.2
Larsson, C.3
-
19
-
-
0037047310
-
Interplay between calcium, diacylglycerol and phosphorylation in the spatial and temporal regulation of PKCα-GFP
-
Tanimura, A., Nezu, A., Morita, T., Hashimoto, N. and Tojyo, Y. (2002) Interplay between calcium, diacylglycerol and phosphorylation in the spatial and temporal regulation of PKCα-GFP. J. Biol. Chem. 277, 29054-29062
-
(2002)
J. Biol. Chem
, vol.277
, pp. 29054-29062
-
-
Tanimura, A.1
Nezu, A.2
Morita, T.3
Hashimoto, N.4
Tojyo, Y.5
-
20
-
-
0032500506
-
An essential role for autophosphorylation in the dissociation of activated protein kinase C from the plasma membrane
-
Feng, X. and Hannun, Y. A. (1998) An essential role for autophosphorylation in the dissociation of activated protein kinase C from the plasma membrane. J. Biol. Chem. 273, 26870-26874
-
(1998)
J. Biol. Chem
, vol.273
, pp. 26870-26874
-
-
Feng, X.1
Hannun, Y.A.2
-
21
-
-
0038758753
-
2 plus vanadate induce reverse translocation of phrbol-ester-activated PKCβII
-
2 plus vanadate induce reverse translocation of phrbol-ester-activated PKCβII. Cell Struct. Funct. 28, 123-130
-
(2003)
Cell Struct. Funct
, vol.28
, pp. 123-130
-
-
Takahashi, H.1
Suzuki, K.2
Namiki, H.3
-
22
-
-
0035163570
-
Ceramide inhibition of NF-κB activation involves reverse translocation of classical protein kinase C (PKC) isoenzymes: Reqirement for kinase activity and carboxyl-terminal phosphorylation of PKC for ceramide response
-
Signorelli, P., Luberto, C. and Hannun, Y. A. (2001) Ceramide inhibition of NF-κB activation involves reverse translocation of classical protein kinase C (PKC) isoenzymes: reqirement for kinase activity and carboxyl-terminal phosphorylation of PKC for ceramide response. FASEB J. 15, 2401-2414
-
(2001)
FASEB J
, vol.15
, pp. 2401-2414
-
-
Signorelli, P.1
Luberto, C.2
Hannun, Y.A.3
-
23
-
-
4143050486
-
Protein kinase Cα translocates to the perinuclear region to activate phospholipase D1
-
Hu, T. and Exton, J. H. (2004) Protein kinase Cα translocates to the perinuclear region to activate phospholipase D1. J. Biol. Chem. 279, 35702-35708
-
(2004)
J. Biol. Chem
, vol.279
, pp. 35702-35708
-
-
Hu, T.1
Exton, J.H.2
-
24
-
-
3142654821
-
Isoenzyme-specific translocation of protein kinase C (PKCβII) and not PKCβI to a juxtanuclear subset of recycling endosomes
-
Becker, P. B. and Hannun, Y. A. (2004) Isoenzyme-specific translocation of protein kinase C (PKCβII) and not PKCβI to a juxtanuclear subset of recycling endosomes. J. Biol. Chem. 279, 28251-28256
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28251-28256
-
-
Becker, P.B.1
Hannun, Y.A.2
-
25
-
-
1842582001
-
Ceramide-induced apoptosis by translocation, phosphorylation and activation of protein kinase Cδ in the Golgi complex
-
Kajimoto, T., Shirai, Y., Sakai, N., Yamamoto, T., Matsuzaki, H., Kikkawa, U. and Saito, N. (2004) Ceramide-induced apoptosis by translocation, phosphorylation and activation of protein kinase Cδ in the Golgi complex. J. Biol. Chem. 279, 12668-12676
-
(2004)
J. Biol. Chem
, vol.279
, pp. 12668-12676
-
-
Kajimoto, T.1
Shirai, Y.2
Sakai, N.3
Yamamoto, T.4
Matsuzaki, H.5
Kikkawa, U.6
Saito, N.7
-
26
-
-
0032568122
-
Identification of a BRCA1-associated kinase with potential biological relevance
-
Burke, T. F., Cocke, K. S., Lemke, S. J., Angleton, E., Becker, G. W. and Beckmann, R. P. (1998) Identification of a BRCA1-associated kinase with potential biological relevance. Oncogene 16, 1031-1040
-
(1998)
Oncogene
, vol.16
, pp. 1031-1040
-
-
Burke, T.F.1
Cocke, K.S.2
Lemke, S.J.3
Angleton, E.4
Becker, G.W.5
Beckmann, R.P.6
-
27
-
-
1642318398
-
Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C βII are mediated by Src-family tyrosine kinases in porcine neutrophils
-
Takahashi, H., Suzuki, K. and Namiki, H. (2004) Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C βII are mediated by Src-family tyrosine kinases in porcine neutrophils. Biochem. Biophys. Res. Commun. 314, 830-837
-
(2004)
Biochem. Biophys. Res. Commun
, vol.314
, pp. 830-837
-
-
Takahashi, H.1
Suzuki, K.2
Namiki, H.3
-
28
-
-
0022970190
-
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes and ras- and sis-transformed normal rat kidney cells
-
Preiss, J., Loomis, C. R., Bishop, W. R., Stein, R., Niedel, J. E. and Bell, R. M. (1986) Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes and ras- and sis-transformed normal rat kidney cells. J. Biol. Chem. 261, 8597-8600
-
(1986)
J. Biol. Chem
, vol.261
, pp. 8597-8600
-
-
Preiss, J.1
Loomis, C.R.2
Bishop, W.R.3
Stein, R.4
Niedel, J.E.5
Bell, R.M.6
-
29
-
-
0028959121
-
Identification, activity and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C
-
Wender, P. A., Irie, K. and Miller, B. L. (1995) Identification, activity and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C. Proc. Natl. Acad. Sci. U.S.A. 92, 239-243
-
(1995)
Proc. Natl. Acad. Sci. U.S.A
, vol.92
, pp. 239-243
-
-
Wender, P.A.1
Irie, K.2
Miller, B.L.3
-
30
-
-
0035131424
-
Subtype-specific translocation of the δ subtype of protein kinase C and its activation by tyrosine phosphorylation induced by ceramide in HeLa cells
-
Kajimoto, T., Ohmori, S., Shirai, Y., Sakai, N. and Saito, N. (2001) Subtype-specific translocation of the δ subtype of protein kinase C and its activation by tyrosine phosphorylation induced by ceramide in HeLa cells. Mol. Cell. Biol. 21, 1769-1783
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 1769-1783
-
-
Kajimoto, T.1
Ohmori, S.2
Shirai, Y.3
Sakai, N.4
Saito, N.5
-
31
-
-
31944435607
-
Targeting of PKC-ε during FcγR-dependent phagocytosis requires the εC1B domain and phospholipase C-γ1
-
Cheeseman, K. L., Ueyama, T., Michaud, T. M., Kashiwagi, K., Wang, D., Flax, L. A., Shirai, Y., Loegering, D. J., Saito, N. and Lennartz, M. R. (2006) Targeting of PKC-ε during FcγR-dependent phagocytosis requires the εC1B domain and phospholipase C-γ1. Mol. Bol. Cell. 17, 799-813
-
(2006)
Mol. Bol. Cell
, vol.17
, pp. 799-813
-
-
Cheeseman, K.L.1
Ueyama, T.2
Michaud, T.M.3
Kashiwagi, K.4
Wang, D.5
Flax, L.A.6
Shirai, Y.7
Loegering, D.J.8
Saito, N.9
Lennartz, M.R.10
-
32
-
-
0037780971
-
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
-
Violin, J. D., Zhang, J., Tsien, R. Y. and Newton, A. C. (2003) A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. J. Cell Biol. 161, 899-909
-
(2003)
J. Cell Biol
, vol.161
, pp. 899-909
-
-
Violin, J.D.1
Zhang, J.2
Tsien, R.Y.3
Newton, A.C.4
-
33
-
-
0035918217
-
Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase Cλ
-
Perander, M., Bjørkøy, G. and Johansen, T. (2001) Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase Cλ. J. Biol. Chem. 276, 13015-13024
-
(2001)
J. Biol. Chem
, vol.276
, pp. 13015-13024
-
-
Perander, M.1
Bjørkøy, G.2
Johansen, T.3
-
34
-
-
0033538433
-
Interplay of C1 and C2 domain of protein kinase C-α in its membrane binding and activation
-
Medkova, M. and Cho, W. (1999) Interplay of C1 and C2 domain of protein kinase C-α in its membrane binding and activation. J. Boil. Chem. 274, 19852-19861
-
(1999)
J. Boil. Chem
, vol.274
, pp. 19852-19861
-
-
Medkova, M.1
Cho, W.2
-
35
-
-
0035830872
-
Roles of ionic residues of the C1 domain in protein kinase C-α activation and the origin of phosphatidylserine specificity
-
Bittova, L., Stahelin, B. V. and Cho, W. (2001) Roles of ionic residues of the C1 domain in protein kinase C-α activation and the origin of phosphatidylserine specificity. J. Biol. Chem. 276, 4218-4226
-
(2001)
J. Biol. Chem
, vol.276
, pp. 4218-4226
-
-
Bittova, L.1
Stahelin, B.V.2
Cho, W.3
-
36
-
-
3142733752
-
Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cδ
-
Stahelin, R. V., Digman, M. A., Medkova, M., Ananthanarayanan, B., Rafter, J. D., Melowic, H. R. and Cho, W. (2004) Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cδ. J. Biol. Chem. 279, 29501-29512
-
(2004)
J. Biol. Chem
, vol.279
, pp. 29501-29512
-
-
Stahelin, R.V.1
Digman, M.A.2
Medkova, M.3
Ananthanarayanan, B.4
Rafter, J.D.5
Melowic, H.R.6
Cho, W.7
-
37
-
-
0026040577
-
The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus
-
Divecha, N., Banfic, H. and Irvine, R. F. (1991) The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J. 10, 3207-3214
-
(1991)
EMBO J
, vol.10
, pp. 3207-3214
-
-
Divecha, N.1
Banfic, H.2
Irvine, R.F.3
-
39
-
-
0037059451
-
Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane
-
Baron, C. L. and Malhotra, V. (2002) Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. Science 295, 325-328
-
(2002)
Science
, vol.295
, pp. 325-328
-
-
Baron, C.L.1
Malhotra, V.2
-
40
-
-
0041488671
-
Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1
-
Bivona, T. G., Perez, De Castro, I., Ahearn, I. M., Grana, T. M., Chiu, V. K., Lockyer, P. J., Cullen, P. J., Pellicer, A., Cox, A. D. and Philips, M. R. (2003) Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1. Nature 424, 694-698
-
(2003)
Nature
, vol.424
, pp. 694-698
-
-
Bivona, T.G.1
Perez, D.2
Castro, I.3
Ahearn, I.M.4
Grana, T.M.5
Chiu, V.K.6
Lockyer, P.J.7
Cullen, P.J.8
Pellicer, A.9
Cox, A.D.10
Philips, M.R.11
-
41
-
-
33847746323
-
A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production
-
Dries, D. R., Gallegos, L. L. and Newton, A. C. (2006) A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production. J. Biol. Chem. 282, 826-830
-
(2006)
J. Biol. Chem
, vol.282
, pp. 826-830
-
-
Dries, D.R.1
Gallegos, L.L.2
Newton, A.C.3
|