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Volumn 20, Issue 6, 2007, Pages 905-912

DC-81-indole conjugate agent induces mitochondria mediated apoptosis in human melanoma A375 cells

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,11A TETRAHYDRO 8 HYDROXY 7 METHOXY 5H PYRROLO[2,1 C][1,4]BENZODIAZEPIN 5 ONE; BENZODIAZEPINE DERIVATIVE; INDOLE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PYRROLO[2,1 C] [1,4]BENZODIAZEPINE; UNCLASSIFIED DRUG;

EID: 34447127577     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx6003387     Document Type: Article
Times cited : (30)

References (27)
  • 1
    • 0017642450 scopus 로고
    • Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin
    • Hurley, L. H. (1977) Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin. J. Antibiot. 30, 349-370.
    • (1977) J. Antibiot , vol.30 , pp. 349-370
    • Hurley, L.H.1
  • 4
    • 0018568879 scopus 로고
    • Proposed structure of the anthramycin-DNA adduct
    • Hurley, L. H., and Petrusek, R. L. (1979) Proposed structure of the anthramycin-DNA adduct. Nature 282, 529-531.
    • (1979) Nature , vol.282 , pp. 529-531
    • Hurley, L.H.1    Petrusek, R.L.2
  • 5
    • 0023819065 scopus 로고
    • 2 adduct. Evidence for two covalent adducts with opposite orientations and stereochemistries at the covalent linkage site
    • 2 adduct. Evidence for two covalent adducts with opposite orientations and stereochemistries at the covalent linkage site. J. Med. Chem. 31, 583-590.
    • (1988) J. Med. Chem , vol.31 , pp. 583-590
    • Cheatham, S.1    Kook, A.2    Hurley, L.H.3    Barkley, M.D.4    Remers, W.5
  • 6
    • 0026746329 scopus 로고
    • Template-directed design of a DNA-DNA cross-linker based upon a bis-tomaymycin-duplex adduct
    • Wang, J. J., Hill, G. C., and Hurley, L. H. (1992) Template-directed design of a DNA-DNA cross-linker based upon a bis-tomaymycin-duplex adduct. J. Med. Chem. 35, 2995-3002.
    • (1992) J. Med. Chem , vol.35 , pp. 2995-3002
    • Wang, J.J.1    Hill, G.C.2    Hurley, L.H.3
  • 7
    • 0028063086 scopus 로고
    • Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: An example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin
    • Mountzouris, J. A., Wang, J. J., Thurston, D. E., and Hurley, L. H. (1994) Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: an example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin. J. Med. Chem. 37, 3132-3140.
    • (1994) J. Med. Chem , vol.37 , pp. 3132-3140
    • Mountzouris, J.A.1    Wang, J.J.2    Thurston, D.E.3    Hurley, L.H.4
  • 8
    • 0016233526 scopus 로고
    • Effects of daunomycin and anthramycin on electrocardiogram and mitochondrial metabolism of the rat heart
    • Cargill, C., Bachmann, E., and Zbinden, G. (1974) Effects of daunomycin and anthramycin on electrocardiogram and mitochondrial metabolism of the rat heart. J. Natl. Cancer Inst. 53, 481-486.
    • (1974) J. Natl. Cancer Inst , vol.53 , pp. 481-486
    • Cargill, C.1    Bachmann, E.2    Zbinden, G.3
  • 9
    • 0000143411 scopus 로고
    • Synthesis of DNA-interactive pyrrolo[2, 1-c][1,4]benzodiazpines
    • Thurston, D. E., and Bose, D. S. (1994) Synthesis of DNA-interactive pyrrolo[2, 1-c][1,4]benzodiazpines. Chem. Rev. 94, 433-465.
    • (1994) Chem. Rev , vol.94 , pp. 433-465
    • Thurston, D.E.1    Bose, D.S.2
  • 10
    • 34447135146 scopus 로고
    • Advances in the Study of Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Antibiotics
    • Neidle, S, and Waring, M. J.,Eds, pp, Macmillan Press, New York
    • Hurley, L H., and Draves, P. H. (1993) Advances in the Study of Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Antibiotics. In Molecular Aspects of the Interaction of (+)-CC-1065 with DNA (Neidle, S., and Waring, M. J.,Eds.) pp 89-133, Macmillan Press, New York.
    • (1993) Molecular Aspects of the Interaction of (+)-CC-1065 with DNA , pp. 89-133
    • Hurley, L.H.1    Draves, P.H.2
  • 12
    • 0034828193 scopus 로고    scopus 로고
    • Design and synthesis of a novel DNA-DNA interstrand adenine-guanine cross-linking agent
    • Zhou, Q., Duan, W., Simmons, D., Shayo, Y., Raymond, M. A., Dorr, R. T., and Hurley, L. H. (2001) Design and synthesis of a novel DNA-DNA interstrand adenine-guanine cross-linking agent. J. Am. Chem, Soc. 123, 4865-4866.
    • (2001) J. Am. Chem, Soc , vol.123 , pp. 4865-4866
    • Zhou, Q.1    Duan, W.2    Simmons, D.3    Shayo, Y.4    Raymond, M.A.5    Dorr, R.T.6    Hurley, L.H.7
  • 13
    • 0022500301 scopus 로고
    • K-252a, a potent inhibitor of protein kinase c from microbial origin
    • Kase, H., Iwahashi, K., and Matsuda, Y. (1986) K-252a, a potent inhibitor of protein kinase c from microbial origin. J. Antibiot. 39, 1059-1065.
    • (1986) J. Antibiot , vol.39 , pp. 1059-1065
    • Kase, H.1    Iwahashi, K.2    Matsuda, Y.3
  • 14
    • 33144473207 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents
    • Wang, J. J., Shen, Y. K., Hu, W. P., Hsieh, M. C., Lin, F. L., Hsu, M. K., and Hsu, M. H. (2006) Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents. J. Med. Chem. 49, 1442-1449.
    • (2006) J. Med. Chem , vol.49 , pp. 1442-1449
    • Wang, J.J.1    Shen, Y.K.2    Hu, W.P.3    Hsieh, M.C.4    Lin, F.L.5    Hsu, M.K.6    Hsu, M.H.7
  • 15
    • 0030932709 scopus 로고    scopus 로고
    • Induction of apoptosis in human T-cells by organomercuric compounds: A flow cytometric analysis
    • Shenker, B. J., Datar, S., Mansfield, K., and Shapiro, I. M. (1997) Induction of apoptosis in human T-cells by organomercuric compounds: A flow cytometric analysis. Toxicol. Appl. Pharmacol. 143, 397-406.
    • (1997) Toxicol. Appl. Pharmacol , vol.143 , pp. 397-406
    • Shenker, B.J.1    Datar, S.2    Mansfield, K.3    Shapiro, I.M.4
  • 17
    • 0023339383 scopus 로고
    • Biology of tumor progression in human melanocytes
    • Herlyn, M., Clark, W. H., and Rodeck, U. (1987) Biology of tumor progression in human melanocytes. Lab. Invest. 56, 461-474.
    • (1987) Lab. Invest , vol.56 , pp. 461-474
    • Herlyn, M.1    Clark, W.H.2    Rodeck, U.3
  • 18
    • 0023792919 scopus 로고
    • Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
    • Scudiero, D. A., Shoemaker, R. H., Paull, K. D., Monks, A., Tierney, S., Nofziger, T. H., Currens, M. J., Seniff, D. D., and Boyd, M. R. (1988) Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res. 48, 4827-4833.
    • (1988) Cancer Res , vol.48 , pp. 4827-4833
    • Scudiero, D.A.1    Shoemaker, R.H.2    Paull, K.D.3    Monks, A.4    Tierney, S.5    Nofziger, T.H.6    Currens, M.J.7    Seniff, D.D.8    Boyd, M.R.9
  • 19
    • 0033564272 scopus 로고    scopus 로고
    • Purified photoproducts of merocyanine 540 trigger cytochrome c release and caspase 8-dependent apoptosis in human leukemia and melanoma cells
    • Pervaiz, S., Seyed, M., Hirpara, J., Clement, M., and Loh, K. (1999) Purified photoproducts of merocyanine 540 trigger cytochrome c release and caspase 8-dependent apoptosis in human leukemia and melanoma cells. Blood 93, 4096-4108.
    • (1999) Blood , vol.93 , pp. 4096-4108
    • Pervaiz, S.1    Seyed, M.2    Hirpara, J.3    Clement, M.4    Loh, K.5
  • 20
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer, G., Dallaporta, B., and Resche-Rigon, M. (1998) The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60, 619-642.
    • (1998) Annu. Rev. Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 21
    • 0025465346 scopus 로고
    • The effect of pH on the toxicity of ammonia to a murine hybridoma
    • Doyle, C., and Butler, M. (1990) The effect of pH on the toxicity of ammonia to a murine hybridoma. J. Biotechnol. 15, 91-100.
    • (1990) J. Biotechnol , vol.15 , pp. 91-100
    • Doyle, C.1    Butler, M.2
  • 22
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997) Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275, 1129-1132.
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6    Peng, T.I.7    Jones, D.P.8    Wang, X.9
  • 23
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 24
    • 0035917337 scopus 로고    scopus 로고
    • An efficient synthesis of pyrrolo[2,1-c]-[1,4]benzodiazepine. Synthesis of the antibiotic DC-81
    • Hu, W. P., Wang, J. J., Lin, F. L., Lin, Y. C., Lin, S. R., and Hsu, M. H. (2001) An efficient synthesis of pyrrolo[2,1-c]-[1,4]benzodiazepine. Synthesis of the antibiotic DC-81. J. Org. Chem. 66, 2881-2883.
    • (2001) J. Org. Chem , vol.66 , pp. 2881-2883
    • Hu, W.P.1    Wang, J.J.2    Lin, F.L.3    Lin, Y.C.4    Lin, S.R.5    Hsu, M.H.6
  • 25
    • 27544493820 scopus 로고    scopus 로고
    • Mutant p53 melanoma cell lines respond differently to CP-31398-induced apoptosis
    • Ho, C. K., and Li, G. (2005) Mutant p53 melanoma cell lines respond differently to CP-31398-induced apoptosis. Br. J. Dermatol. 153, 900-910.
    • (2005) Br. J. Dermatol , vol.153 , pp. 900-910
    • Ho, C.K.1    Li, G.2
  • 27
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.