-
1
-
-
10744229097
-
GENIS: Gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo
-
BARTON, K.N., TYSON, D., STRICKER, H., LEW, Y.S., HEISEY, G., KOUL, S., DE LA ZERDA, A., YIN, F.F., YAN, H., NAGARAJA, T.N., RANDALL, K.A., JIN, G.K., FENSTERMACHER, J.D., JHIANG, S., KIM, J.H., FREYTAG, S.O., and BROWN, S.L. (2003). GENIS: Gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo. Mol. Ther. 8, 508-518.
-
(2003)
Mol. Ther
, vol.8
, pp. 508-518
-
-
BARTON, K.N.1
TYSON, D.2
STRICKER, H.3
LEW, Y.S.4
HEISEY, G.5
KOUL, S.6
DE LA ZERDA, A.7
YIN, F.F.8
YAN, H.9
NAGARAJA, T.N.10
RANDALL, K.A.11
JIN, G.K.12
FENSTERMACHER, J.D.13
JHIANG, S.14
KIM, J.H.15
FREYTAG, S.O.16
BROWN, S.L.17
-
2
-
-
2342640954
-
A quantitative method for measuring gene expression magnitude and volume delivered by gene therapy vectors
-
BARTON, K.N., XIA, X., YAN, H., STRICKER, H., HEISEY, G., YIN, F.F., NAGARAJA, T.N., ZHU, G., KOLOZSVARY, A., FENSTERMACHER, J.D., LU, M., KIM, J.H., FREYTAG, S.O., and BROWN, S.L. (2004). A quantitative method for measuring gene expression magnitude and volume delivered by gene therapy vectors. Mol. Ther. 9, 625-631.
-
(2004)
Mol. Ther
, vol.9
, pp. 625-631
-
-
BARTON, K.N.1
XIA, X.2
YAN, H.3
STRICKER, H.4
HEISEY, G.5
YIN, F.F.6
NAGARAJA, T.N.7
ZHU, G.8
KOLOZSVARY, A.9
FENSTERMACHER, J.D.10
LU, M.11
KIM, J.H.12
FREYTAG, S.O.13
BROWN, S.L.14
-
3
-
-
30344477005
-
Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity
-
BARTON, K.N., PAIELLI, D., ZHANG, Y., KOUL, S., BROWN, S.L., LU, M., SEELY, J., KIM, J.H., and FREYTAG, S.O. (2006a). Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity. Mol. Ther. 13, 347-356.
-
(2006)
Mol. Ther
, vol.13
, pp. 347-356
-
-
BARTON, K.N.1
PAIELLI, D.2
ZHANG, Y.3
KOUL, S.4
BROWN, S.L.5
LU, M.6
SEELY, J.7
KIM, J.H.8
FREYTAG, S.O.9
-
4
-
-
33645980624
-
Polyethylene glycol (molecular weight 400 DA) vehicle improves gene expression of adenovirus mediated gene therapy
-
BARTON, K.N., STRICKER, H., KOLOZSVARY, A., KOHL, R., HEISEY, G., NAGARAJA, T.N., ZHU, G., LU, M., KIM, J.H., FREYTAG, S.O., and BROWN, S.L. (2006b). Polyethylene glycol (molecular weight 400 DA) vehicle improves gene expression of adenovirus mediated gene therapy. J. Urol. 175, 1921-1925.
-
(2006)
J. Urol
, vol.175
, pp. 1921-1925
-
-
BARTON, K.N.1
STRICKER, H.2
KOLOZSVARY, A.3
KOHL, R.4
HEISEY, G.5
NAGARAJA, T.N.6
ZHU, G.7
LU, M.8
KIM, J.H.9
FREYTAG, S.O.10
BROWN, S.L.11
-
6
-
-
0035879042
-
CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity
-
CHEN, Y., DEWEESE, T., DILLEY, J., ZHANG, Y., LI, Y., RAMESH, N., LEE, J., PENNATHUR-DAS, R., RADZYMINSKI, J., WYPYCH, J., BRIGNETTI, D., SCOTT, S., STEPHENS, J., KARPF, D.B., HENDERSON, D.R., and YU, D.C. (2001). CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity. Cancer Res. 61, 5453-5460.
-
(2001)
Cancer Res
, vol.61
, pp. 5453-5460
-
-
CHEN, Y.1
DEWEESE, T.2
DILLEY, J.3
ZHANG, Y.4
LI, Y.5
RAMESH, N.6
LEE, J.7
PENNATHUR-DAS, R.8
RADZYMINSKI, J.9
WYPYCH, J.10
BRIGNETTI, D.11
SCOTT, S.12
STEPHENS, J.13
KARPF, D.B.14
HENDERSON, D.R.15
YU, D.C.16
-
7
-
-
0035887153
-
A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
-
DEWEESE, T.L., VAN DER POEL, H., LI, S., MIKHAK, B., DREW, R., GOEMANN, M., HAMPER, U., DEJONG, R., DETORIE, N., RODRIGUEZ, R., HAULK, T., DEMARZO, A.M., PIANTADOSI, S., YU, D.C., CHEN, Y., HENDERSON, D.R., CARDUCCI, M.A., NELSON, W.G., and SIMONS, J.W. (2001). A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res. 61, 7464-7472.
-
(2001)
Cancer Res
, vol.61
, pp. 7464-7472
-
-
DEWEESE, T.L.1
VAN DER POEL, H.2
LI, S.3
MIKHAK, B.4
DREW, R.5
GOEMANN, M.6
HAMPER, U.7
DEJONG, R.8
DETORIE, N.9
RODRIGUEZ, R.10
HAULK, T.11
DEMARZO, A.M.12
PIANTADOSI, S.13
YU, D.C.14
CHEN, Y.15
HENDERSON, D.R.16
CARDUCCI, M.A.17
NELSON, W.G.18
SIMONS, J.W.19
-
8
-
-
22944434253
-
Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity
-
DILLEY, J., REDDY, S., KO, D., NGUYEN, N., ROJAS, G., WORKING, P., and YU, D.C. (2005). Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity. Cancer Gene Ther. 12, 715-722.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 715-722
-
-
DILLEY, J.1
REDDY, S.2
KO, D.3
NGUYEN, N.4
ROJAS, G.5
WORKING, P.6
YU, D.C.7
-
9
-
-
0032503659
-
A novel three-pronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy
-
FREYTAG, S.O., ROGULSKI, K.R., PAIELLI, D.L., GILBERT, J.D., and KIM, J.H. (1998). A novel three-pronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy. Hum. Gene Ther. 9, 1323-1333.
-
(1998)
Hum. Gene Ther
, vol.9
, pp. 1323-1333
-
-
FREYTAG, S.O.1
ROGULSKI, K.R.2
PAIELLI, D.L.3
GILBERT, J.D.4
KIM, J.H.5
-
10
-
-
0010349948
-
Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model
-
FREYTAG, S.O., PAIELLI, D., WING, M., ROGULSKI, K., BROWN, S., KOLOZSVARY, A., SEELY, J., BARTON, K., DRAGOVIC, A., and KIM, J.H. (2002a). Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model. Int. J. Radiat. Oncol. Biol. Phys. 54, 873-885.
-
(2002)
Int. J. Radiat. Oncol. Biol. Phys
, vol.54
, pp. 873-885
-
-
FREYTAG, S.O.1
PAIELLI, D.2
WING, M.3
ROGULSKI, K.4
BROWN, S.5
KOLOZSVARY, A.6
SEELY, J.7
BARTON, K.8
DRAGOVIC, A.9
KIM, J.H.10
-
11
-
-
0036733759
-
Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer
-
FREYTAG, S.O., KHIL, M., STRICKER, H., PEABODY, J., MENON, M., DEPERALTA-VENTURINA, M., NAFZIGER, D., PEGG, J., PAIELLI, D., BROWN, S., BARTON, K., LU, M., AGUILAR-CORDOVA, E., and KIM, J.H. (2002b). Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res. 62, 4968-4976.
-
(2002)
Cancer Res
, vol.62
, pp. 4968-4976
-
-
FREYTAG, S.O.1
KHIL, M.2
STRICKER, H.3
PEABODY, J.4
MENON, M.5
DEPERALTA-VENTURINA, M.6
NAFZIGER, D.7
PEGG, J.8
PAIELLI, D.9
BROWN, S.10
BARTON, K.11
LU, M.12
AGUILAR-CORDOVA, E.13
KIM, J.H.14
-
12
-
-
10744227813
-
Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer
-
FREYTAG, S.O., STRICKER, H., PEGG, J., PAIELLI, D., PRADHAN, D.G., PEABODY, J., DEPERALTA-VENTURINA, M., XIA, X., BROWN, S., LU, M., and KIM, J.H. (2003). Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer Res. 63, 7497-7506.
-
(2003)
Cancer Res
, vol.63
, pp. 7497-7506
-
-
FREYTAG, S.O.1
STRICKER, H.2
PEGG, J.3
PAIELLI, D.4
PRADHAN, D.G.5
PEABODY, J.6
DEPERALTA-VENTURINA, M.7
XIA, X.8
BROWN, S.9
LU, M.10
KIM, J.H.11
-
13
-
-
34247218184
-
Phase I trial of replication-competent adenovirus-mediated suicide gene therapy combined with IMRT for prostate cancer
-
FREYTAG, S.O., MOVSAS, B., AREF, I., STRICKER, H., PEABODY, J., PEGG, J., ZHANG, Y., BARTON, K.N., BROWN, S.L., LU, M., SAVERA, A., and KIM, J.H. (2007a). Phase I trial of replication-competent adenovirus-mediated suicide gene therapy combined with IMRT for prostate cancer. Mol. Ther. 15, 1016-1023.
-
(2007)
Mol. Ther
, vol.15
, pp. 1016-1023
-
-
FREYTAG, S.O.1
MOVSAS, B.2
AREF, I.3
STRICKER, H.4
PEABODY, J.5
PEGG, J.6
ZHANG, Y.7
BARTON, K.N.8
BROWN, S.L.9
LU, M.10
SAVERA, A.11
KIM, J.H.12
-
14
-
-
33847212832
-
Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer
-
FREYTAG, S.O., STRICKER, H., PEABODY, J., PEGG, J., PAIELLI, D., MOVSAS, B., BARTON, K.N., BROWN, S.L., LU, M., and KIM, J.H. (2007b). Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer. Mol. Ther. 15, 636-642.
-
(2007)
Mol. Ther
, vol.15
, pp. 636-642
-
-
FREYTAG, S.O.1
STRICKER, H.2
PEABODY, J.3
PEGG, J.4
PAIELLI, D.5
MOVSAS, B.6
BARTON, K.N.7
BROWN, S.L.8
LU, M.9
KIM, J.H.10
-
15
-
-
0037215367
-
Dosimetric and technical considerations for interstitial adenoviral gene therapy as applied to prostate cancer
-
LI, S., SIMONS, J., DETORIE, N., O'ROURKE, B., HAMPER, U., and DEWEESE, T.L. (2003). Dosimetric and technical considerations for interstitial adenoviral gene therapy as applied to prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 55, 204-214.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys
, vol.55
, pp. 204-214
-
-
LI, S.1
SIMONS, J.2
DETORIE, N.3
O'ROURKE, B.4
HAMPER, U.5
DEWEESE, T.L.6
-
16
-
-
0033984339
-
Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization
-
ROGULSKI, K.R., WING, M.S., PAIELLI, D.L., GILBERT, J.D., KIM, J.H., and FREYTAG, S.O. (2000a). Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. Hum. Gene Ther. 11, 67-76.
-
(2000)
Hum. Gene Ther
, vol.11
, pp. 67-76
-
-
ROGULSKI, K.R.1
WING, M.S.2
PAIELLI, D.L.3
GILBERT, J.D.4
KIM, J.H.5
FREYTAG, S.O.6
-
17
-
-
0034161976
-
In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy
-
ROGULSKI, K.R., FREYTAG, S.O., ZHANG, K., GILBERT, J.D., PAIELLI, D.L., KIM, J.H., HEISE, C.C., and KIRN, D.H. (2000b). In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy. Cancer Res. 60, 1193-1196.
-
(2000)
Cancer Res
, vol.60
, pp. 1193-1196
-
-
ROGULSKI, K.R.1
FREYTAG, S.O.2
ZHANG, K.3
GILBERT, J.D.4
PAIELLI, D.L.5
KIM, J.H.6
HEISE, C.C.7
KIRN, D.H.8
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