Polyethylene Glycol (Molecular Weight 400 DA) Vehicle Improves Gene Expression of Adenovirus Mediated Gene Therapy

Journal of Urology

Volumn 175, Issue 5, 2006, Pages 1921-1925

  Barton, K N ^a   Stricker, H ^a   Kolozsvary, A ^a   Kohl, R ^a   Heisey, G ^a   Nagaraja, T N ^a   Zhu, G ^a   Lu, M ^a   Kim, J H ^a   Freytag, S O ^a   Brown, S L ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Adenoviridae; dogs; gene therapy; polyethylene glycols; prostate

Indexed keywords

ADENOVIRUS VECTOR; MACROGOL 400; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CONTROL; CANCER INHIBITION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOG; FLUORESCENCE; GENE EXPRESSION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; SUICIDE GENE THERAPY; TRANSGENE; TUMOR GROWTH; TUMOR XENOGRAFT; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; DRUG CARRIERS; GENE EXPRESSION REGULATION, VIRAL; GENE THERAPY; POLYETHYLENE GLYCOLS;

EID: 33645980624     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)00918-3     Document Type: Article

References (19)

1. Freytag S.O., Kim J.H., Brown S.L., Barton K., Lu M., and Chung M. Gene therapy strategies to improve the effectiveness of cancer radiotherapy. Expert Opin Biol Ther 4 (2004) 1757
2. Wiewrodt R., Amin K., Kiefer M., Jovanovic V.P., Kapoor V., Force S., et al. Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing. Cancer Gene Ther 10 (2003) 353
3. Siemens D.R., Austin J.C., Hedican S.P., Tartaglia J., and Ratliff T.L. Viral vector delivery in solid-state vehicles. gene expression in a murine prostate cancer model. J Natl Cancer Inst 92 (2000) 403
4. Croyle M.A., Cheng X., Sandhu A., and Wilson J.M. Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo. Mol Ther 4 (2001) 22
5. Freytag S.O., Khil M., Stricker H., Peabody J., Menon M., DePeralta-Venturina M., et al. Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res 62 (2002) 4968
6. Barton K.N., Tyson D., Stricker H., Lew Y.S., Heisey G., Koul S., et al. GENIS. gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo. Mol Ther 8 (2003) 508
7. Barton K.N., Xia X., Yan H., Stricker H., Heisey G., Yin F.F., et al. A quantitative method for measuring gene expression magnitude and volume delivered by gene therapy vectors. Mol Ther 9 (2004) 625
8. Andrawiss M., Opolon P., Benihoud K., Devauchelle P., Di Falco N., Villette J.M., et al. Adenovirus-mediated gene transfer in dog prostate. a preclinical study of a relevant model system for gene therapy of human prostatic cancer. Prostate Cancer Prostatic Dis 2 (1999) 25
9. Fisher R.A. Statistical Methods for Research Workers (1925), Oliver and Boyd, Edinburgh
10. Beer S.J., Matthews C.B., Stein C.S., Ross B.D., Hilfinger J.M., and Davidson B.L. Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo. Gene Ther 5 (1998) 740
11. Ohsawa T., Nakamura T., Mihara M., and Sato K. Enhancement of adenovirus-mediated gene transfer into dermal fibroblasts in vitro and in vivo by polyethylene glycol 6000. J Dermatol 27 (2000) 244
12. Toyoda K., Ooboshi H., Chu Y., Fasbender A., Davidson B.L., Welsh M.J., et al. Cationic polymer and lipids enhance adenovirus-mediated gene transfer to rabbit carotid artery. Stroke 29 (1998) 2181
13. Feorino P.M., and Hannon W.H. Use of DEAE dextran in agar overlays to enhance size of ECHO virus plaques. Public Health Rep 81 (1966) 1015
14. Kaplan J.M., Pennington S.E., St George J.A., Woodworth L.A., Fasbender A., Marshall J., et al. Potentiation of gene transfer to the mouse lung by complexes of adenovirus vector and polycations improves therapeutic potential. Hum Gene Ther 9 (1998) 1469
15. Gregory L.G., Harbottle R.P., Lawrence L., Knapton H.J., Themis M., and Coutelle C. Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo. Mol Ther 7 (2003) 19
16. Siemens D.R., Iwasawa T., Austin J.C., Williams R.D., See W.A., Hedican S.P., et al. Biomarker distribution after injection into the canine prostate. implications for gene therapy. BJU 86 (2000) 1076
17. March K.L., Madison J.E., and Trapnell B.C. Pharmacokinetics of adenoviral vector-mediated gene delivery to vascular smooth muscle cells. modulation by poloxamer 407 and implications for cardiovascular therapy. Hum Gene Ther 6 (1995) 41
18. Fasbender A., Zabner J., Chillon M., Moninger T.O., Puga A.P., Davidson B.L., et al. Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo. J Biol Chem 272 (1997) 6479
19. Croyle M.A., Yu Q.C., and Wilson J.M. Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. Hum Gene Ther 11 (2000) 1713