P-selectin mediates reperfusion injury through neutrophil and platelet sequestration in the warm ischemic mouse liver

Hepatology

Volumn 29, Issue 5, 1999, Pages 1494-1502

  Kashyap, Surinder S ^a  

^a Division of Liver Transplantation and Hepatobiliary Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; PADGEM PROTEIN;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CYTOTOXICITY; IMMUNOHISTOCHEMISTRY; LEUKOCYTE ADHERENCE; LIVER INJURY; LIVER ISCHEMIA; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REPERFUSION INJURY; SURVIVAL; THROMBOCYTE ADHESION;

ANIMALS; BLOOD PLATELETS; CELL ADHESION; ISCHEMIA; LIVER; LIVER CIRCULATION; MICE; MICE, INBRED C57BL; NEUTROPHILS; P-SELECTIN; REPERFUSION INJURY; SURVIVAL ANALYSIS; TRANSAMINASES;

EID: 0032955559     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290505     Document Type: Article

References (5)

1. Granger ND, Korthuis RJ. Physiologic mechanism of postischemic tissue injury. Annu Rev Physiol 1995;57:311-332.
2. Clavien PA, Harvey PR, Strasberg SM. Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies. Transplantation 1992;53:957-978.
3. Camargo CAJ, Madden JF, Gao W, Selvan RS, Clavien P-A. Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. HEPATOLOGY 1997;26:1513-1520.
4. Clavien PA. IL-6, a key cytokine in liver regeneration. HEPATOLOGY 1997;25:1294-1296.
5. Jaeschke H, Baustista AP, Spolarics Z, Spitzer JJ. Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia. Free Radic Res Commun 1991;15:277-285.