On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs

Biophysical Chemistry

Volumn 129, Issue 1, 2007, Pages 56-59

  Kostjukov, V V ^a   Lantushenko, A O ^a   Davies, D B ^b   Evstigneev, M P ^a  

^a SEVASTOPOL STATE UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Aromatic ligand; d(GCGAAGC); Molecular dynamics; Thermal stability; Water bridges

Indexed keywords

ADENINE; AROMATIC COMPOUND; CYTOSINE; DAUNORUBICIN; DNA; DOUBLE STRANDED DNA; ETHIDIUM BROMIDE; GUANINE; MITOXANTRONE; PROFLAVINE;

ANALYTIC METHOD; ARTICLE; COMPLEX FORMATION; DNA BINDING; DNA DRUG COMPLEX; HYDRATION; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; THERMOSTABILITY;

BASE SEQUENCE; BINDING SITES; DAUNORUBICIN; DNA; ETHIDIUM; HEAT; HYDROCARBONS, AROMATIC; MITOXANTRONE; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; PHARMACEUTICAL PREPARATIONS; PROFLAVINE; THERMODYNAMICS; WATER;

EID: 34347400649     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2007.05.005     Document Type: Article

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