1H-NMR determination of the thermodynamics of drug complexation with single-stranded and double-stranded oligonucleotides in solution: Ethidium bromide complexation with the deoxytetranucleotides 5′-d(ApCpGpT), 5′-d(ApGpCpT), and 5′-d(TpGpCpA)

Biopolymers - Nucleic Acid Sciences Section

Volumn 42, Issue 3, 1997, Pages 285-295

  Davies, D B ^a   Djimant, L N ^b   Baranovsky, S F ^a   Veselkov, A N ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b SEVASTOPOL STATE UNIVERSITY   (Russian Federation)

Author keywords

'h nmr of drug binding; Ethidium bromide binding (ag, ah, as,); Intercalation of ethidium bromide; Oligodeoxynucleotides; Thermodynamic parameters of drug binding

Indexed keywords

BROMINE COMPOUNDS; COMPLEXATION; ELECTROSTATICS; ENTHALPY; ENTROPY; FREE ENERGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS; PROTONS; SOLUTIONS; THERMAL EFFECTS; VAN DER WAALS FORCES;

DEOXYTETRANUCLEOTIDES; ETHIDIUM BROMIDE; OLIGONUCLEOTIDES;

DRUG PRODUCTS;

ETHIDIUM BROMIDE; OLIGONUCLEOTIDE; TETRAMER; ETHIDIUM; INTERCALATING AGENT; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; COMPLEX FORMATION; DRUG BINDING; ENTHALPY; ENTROPY; PROTON NUCLEAR MAGNETIC RESONANCE; THERMODYNAMICS; BINDING SITE; CHEMISTRY; DNA BASE COMPOSITION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TEMPERATURE;

BASE COMPOSITION; BINDING SITES; ETHIDIUM; INTERCALATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; OLIGODEOXYRIBONUCLEOTIDES; TEMPERATURE; THERMODYNAMICS;

EID: 0031215266     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0282(199709)42:3<285::aid-bip2>3.0.co;2-i     Document Type: Article

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