A novel synthesis of 2,5-disubstituted 1,3,4-oxadiazolines by the regioselective cyclization of 1,4-disubstituted thiosemicarbazides

Synthesis

Volumn , Issue 12, 2007, Pages 1779-1784

  Feng, Dexin ^a   Huang, You ^a   Chen, Ruyu ^a   Yu, Yaqin ^a   Song, Haibin ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

Cyclization; Desulfurization; Oxadiazole; Regioselective; Thiosemicarbazide

Indexed keywords

REGIOSELECTIVE SYNTHESIS; TRANS-ISOMER;

CYCLIZATION; DESULFURIZATION; REGIOSELECTIVITY; SYNTHESIS (CHEMICAL);

AROMATIC HYDROCARBONS;

1 BENZOYL 4 [(4 ARYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)THIOSEMICARBAZIDE; 1,3,4 OXADIAZOLE DERIVATIVE; 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (2 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (3 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (4 METHOXYPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (4 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 PHENYL 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (2 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (3 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (4 METHOXYPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE5; 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 (4 METHYLPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 5 PHENYL 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 2 [(4 CHLOROPHENYL 5,5 DIMETHYL 2 OXO 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 2,3 DIHYDRO 1,3,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 2 [(5,5 DIMETHYL 2 OXO 4 PHENYL 1,3,2 DIOXAPHOSPHINAN 2 YL)IMINO] 2,3 DIHYDRO 1,3,4 OXADIAZOLE; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; ISOMERIZATION; NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE;

EID: 34347393323     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-983714     Document Type: Article

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