-
1
-
-
2942689783
-
Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice
-
Alonzi T, Agrati C, Costabile B, Cicchini C, Amicone L, Cavallari C, Rocca CD, Folgori A, Fipaldini C, Poccia F, Monica NL, Tripodi M. 2004. Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice. J Gen Virol 85:1509-1520.
-
(2004)
J Gen Virol
, vol.85
, pp. 1509-1520
-
-
Alonzi, T.1
Agrati, C.2
Costabile, B.3
Cicchini, C.4
Amicone, L.5
Cavallari, C.6
Rocca, C.D.7
Folgori, A.8
Fipaldini, C.9
Poccia, F.10
Monica, N.L.11
Tripodi, M.12
-
2
-
-
0029075822
-
Co-regulation of two gene activities by tetracycline via a bidirectional promoter
-
Baron U, Freundlieb S, Gossen M, Bujard H. 1995. Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res 23:3605-3606.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3605-3606
-
-
Baron, U.1
Freundlieb, S.2
Gossen, M.3
Bujard, H.4
-
3
-
-
0029021814
-
Selection of recombinant vaccinia viruses on the basis of plaque formation
-
Blasco R, Moss B. 1995. Selection of recombinant vaccinia viruses on the basis of plaque formation. Gene 158:157-162.
-
(1995)
Gene
, vol.158
, pp. 157-162
-
-
Blasco, R.1
Moss, B.2
-
4
-
-
0037621934
-
Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice
-
Blindenbacher A, Duong FH, Hunziker L, Stutvoet ST, Wang X, Terracciano L, Moradpour D, Blum HE, Alonzi T, Tripodi M, La Monica N, Heim MH. 2003. Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice. Gastroenterology 124:1465-1475.
-
(2003)
Gastroenterology
, vol.124
, pp. 1465-1475
-
-
Blindenbacher, A.1
Duong, F.H.2
Hunziker, L.3
Stutvoet, S.T.4
Wang, X.5
Terracciano, L.6
Moradpour, D.7
Blum, H.E.8
Alonzi, T.9
Tripodi, M.10
La Monica, N.11
Heim, M.H.12
-
5
-
-
0024487141
-
Insertional mutations in transgenic mice
-
Costantini F, Radice G, Lee JL, Chada KK, Perry W, Son HJ. 1989. Insertional mutations in transgenic mice. Prog Nucleic Acid Res Mol Biol 36:159-169.
-
(1989)
Prog Nucleic Acid Res Mol Biol
, vol.36
, pp. 159-169
-
-
Costantini, F.1
Radice, G.2
Lee, J.L.3
Chada, K.K.4
Perry, W.5
Son, H.J.6
-
6
-
-
10744232784
-
Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein
-
Disson O, Haouzi D, Desagher S, Loesch K, Hahne M, Kremer EJ, Jacquet C, Lemon SM, Hibner U, Lerat H. 2004. Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein. Gastroenterology 126:859-872.
-
(2004)
Gastroenterology
, vol.126
, pp. 859-872
-
-
Disson, O.1
Haouzi, D.2
Desagher, S.3
Loesch, K.4
Hahne, M.5
Kremer, E.J.6
Jacquet, C.7
Lemon, S.M.8
Hibner, U.9
Lerat, H.10
-
7
-
-
0037334936
-
CpG immunostimulatory motifs enhance humoral immune responses against hepatitis C virus core protein after DNA-based immunization
-
Encke J, zu Putlitz J, Stremmel W, Wands JR. 2003. CpG immunostimulatory motifs enhance humoral immune responses against hepatitis C virus core protein after DNA-based immunization. Arch Virol 148:435-448.
-
(2003)
Arch Virol
, vol.148
, pp. 435-448
-
-
Encke, J.1
zu Putlitz, J.2
Stremmel, W.3
Wands, J.R.4
-
8
-
-
0036157469
-
Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T lymphocyte population
-
Estcourt MJ, Ramsay AJ, Brooks A, Thomson SA, Medveckzy CJ, Ramshaw IA. 2002. Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T lymphocyte population. Int Immunol 14:31-37.
-
(2002)
Int Immunol
, vol.14
, pp. 31-37
-
-
Estcourt, M.J.1
Ramsay, A.J.2
Brooks, A.3
Thomson, S.A.4
Medveckzy, C.J.5
Ramshaw, I.A.6
-
9
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M, Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547-5551.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
11
-
-
0035089060
-
Long-term, noninvasive imaging of regulated gene expression in living mice
-
Hasan MT, Schonig K, Berger S, Graewe W, Bujard H. 2001. Long-term, noninvasive imaging of regulated gene expression in living mice. Genesis 29:116-122.
-
(2001)
Genesis
, vol.29
, pp. 116-122
-
-
Hasan, M.T.1
Schonig, K.2
Berger, S.3
Graewe, W.4
Bujard, H.5
-
12
-
-
0029692895
-
Inactivation of hepatitis C virus cDNA transgene by hypermethylation in transgenic mice
-
Kato T, Ahmed M, Yamamoto T, Takahashi H, Oohara M, Ikeda T, Aida Y, Katsuki M, Arakawa Y, Shikata T, Esumi M. 1996. Inactivation of hepatitis C virus cDNA transgene by hypermethylation in transgenic mice. Arch Virol 141:951-958.
-
(1996)
Arch Virol
, vol.141
, pp. 951-958
-
-
Kato, T.1
Ahmed, M.2
Yamamoto, T.3
Takahashi, H.4
Oohara, M.5
Ikeda, T.6
Aida, Y.7
Katsuki, M.8
Arakawa, Y.9
Shikata, T.10
Esumi, M.11
-
13
-
-
10744233450
-
Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice
-
Kato T, Miyamoto M, Date T, Yasui K, Taya C, Yonekawa H, Ohue C, Yagi S, Seki E, Hirano T, Fujimoto J, Shirai T, Wakita T. 2003. Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice. Cancer Sci 94:679-685.
-
(2003)
Cancer Sci
, vol.94
, pp. 679-685
-
-
Kato, T.1
Miyamoto, M.2
Date, T.3
Yasui, K.4
Taya, C.5
Yonekawa, H.6
Ohue, C.7
Yagi, S.8
Seki, E.9
Hirano, T.10
Fujimoto, J.11
Shirai, T.12
Wakita, T.13
-
14
-
-
0030940874
-
Transgenic expression of hepatitis C virus structural proteins in the mouse
-
Kawamura T, Furusaka A, Koziel MJ, Chung RT, Wang TC, Schmidt EV, Liang TJ. 1997. Transgenic expression of hepatitis C virus structural proteins in the mouse. Hepatology 25:1014-1021.
-
(1997)
Hepatology
, vol.25
, pp. 1014-1021
-
-
Kawamura, T.1
Furusaka, A.2
Koziel, M.J.3
Chung, R.T.4
Wang, T.C.5
Schmidt, E.V.6
Liang, T.J.7
-
15
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
Kistner A, Gossen M, Zimmermann F, Jerecic J, Ullmer C, Lubbert H, Bujard H. 1996. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci USA 93:10933-10938.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10933-10938
-
-
Kistner, A.1
Gossen, M.2
Zimmermann, F.3
Jerecic, J.4
Ullmer, C.5
Lubbert, H.6
Bujard, H.7
-
16
-
-
0036097130
-
Role of hepatitis C virus in the development of hepatocellular carcinoma: Transgenic approach to viral hepatocarcinogenesis
-
Koike K, Moriya K, Kimura S. 2002. Role of hepatitis C virus in the development of hepatocellular carcinoma: Transgenic approach to viral hepatocarcinogenesis. J Gastroenterol Hepatol 17:394-400.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 394-400
-
-
Koike, K.1
Moriya, K.2
Kimura, S.3
-
17
-
-
0036346427
-
Advances in model systems for hepatitis C virus research
-
Lanford RE, Bigger C. 2002. Advances in model systems for hepatitis C virus research. Virology 293:1-9.
-
(2002)
Virology
, vol.293
, pp. 1-9
-
-
Lanford, R.E.1
Bigger, C.2
-
18
-
-
0036158719
-
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
-
Lerat H, Honda M, Beard MR, Loesch K, Sun J, Yang Y, Okuda M, Gosert R, Xiao SY, Weinman SA, Lemon SM. 2002. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterol 122:352-365.
-
(2002)
Gastroenterol
, vol.122
, pp. 352-365
-
-
Lerat, H.1
Honda, M.2
Beard, M.R.3
Loesch, K.4
Sun, J.5
Yang, Y.6
Okuda, M.7
Gosert, R.8
Xiao, S.Y.9
Weinman, S.A.10
Lemon, S.M.11
-
19
-
-
0031940344
-
Transgenic mouse expressing a full-length hepatitis C virus cDNA
-
Matsuda J, Suzuki M, Nozaki C, Shinya N, Tashiro K, Mizuno K, Uchinuno Y, Yamamura K. 1998. Transgenic mouse expressing a full-length hepatitis C virus cDNA. Jpn J Cancer Res 89:150-158.
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 150-158
-
-
Matsuda, J.1
Suzuki, M.2
Nozaki, C.3
Shinya, N.4
Tashiro, K.5
Mizuno, K.6
Uchinuno, Y.7
Yamamura, K.8
-
20
-
-
0030859121
-
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
-
Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, Miyamura T, Koike K. 1997. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 78:1527-1531.
-
(1997)
J Gen Virol
, vol.78
, pp. 1527-1531
-
-
Moriya, K.1
Yotsuyanagi, H.2
Shintani, Y.3
Fujie, H.4
Ishibashi, K.5
Matsuura, Y.6
Miyamura, T.7
Koike, K.8
-
21
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Ishibashi K, Matsuura Y, Kimura S, Miyamura T, Koike K. 1998. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 4:1065-1067.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
Yotsuyanagi, H.4
Tsutsumi, T.5
Ishibashi, K.6
Matsuura, Y.7
Kimura, S.8
Miyamura, T.9
Koike, K.10
-
22
-
-
0035360859
-
Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis
-
Moriya K, Nakagawa K, Santa T, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Miyazawa T, Ishibashi K, Horie T, Imai K, Todoroki T, Kimura S, Koike K. 2001. Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis. Cancer Res 61:4365-4370.
-
(2001)
Cancer Res
, vol.61
, pp. 4365-4370
-
-
Moriya, K.1
Nakagawa, K.2
Santa, T.3
Shintani, Y.4
Fujie, H.5
Miyoshi, H.6
Tsutsumi, T.7
Miyazawa, T.8
Ishibashi, K.9
Horie, T.10
Imai, K.11
Todoroki, T.12
Kimura, S.13
Koike, K.14
-
23
-
-
0031057659
-
Hepatitis C virus core and E2 protein expression in transgenic mice
-
Pasquinelli C, Shoenberger JM, Chung J, Chang KM, Guidotti LG, Selby M, Berger K, Lesniewski R, Houghton M, Chisari FV. 1997. Hepatitis C virus core and E2 protein expression in transgenic mice. Hepatology 25:719-727.
-
(1997)
Hepatology
, vol.25
, pp. 719-727
-
-
Pasquinelli, C.1
Shoenberger, J.M.2
Chung, J.3
Chang, K.M.4
Guidotti, L.G.5
Selby, M.6
Berger, K.7
Lesniewski, R.8
Houghton, M.9
Chisari, F.V.10
-
24
-
-
0346874205
-
Alcohol and hepatitis C virus core protein additively increase lipid peroxidation and synergistically trigger hepatic cytokine expression in a transgenic mouse model
-
Perlemuter G, Letteron P, Carnot F, Zavala F, Pessayre D, Nalpas B, Brechot C. 2003. Alcohol and hepatitis C virus core protein additively increase lipid peroxidation and synergistically trigger hepatic cytokine expression in a transgenic mouse model. J Hepatol 39:1020-1027.
-
(2003)
J Hepatol
, vol.39
, pp. 1020-1027
-
-
Perlemuter, G.1
Letteron, P.2
Carnot, F.3
Zavala, F.4
Pessayre, D.5
Nalpas, B.6
Brechot, C.7
-
25
-
-
0034176364
-
The prime-boost strategy: Exciting prospects for improved vaccination
-
Ramshaw IA, Ramsay AJ. 2000. The prime-boost strategy: Exciting prospects for improved vaccination. Immunol Today 21:163-165.
-
(2000)
Immunol Today
, vol.21
, pp. 163-165
-
-
Ramshaw, I.A.1
Ramsay, A.J.2
-
26
-
-
0030914741
-
Plasmid DNA-based immunization for hepatitis C virus structural proteins: Immune responses in mice
-
Saito T, Sherman GJ, Kurokohchi K, Guo ZP, Donets M, Yu MY, Berzofsky JA, Akatsuka T, Feinstone SM. 1997. Plasmid DNA-based immunization for hepatitis C virus structural proteins: Immune responses in mice. Gastroenterol 112:1321-1330.
-
(1997)
Gastroenterol
, vol.112
, pp. 1321-1330
-
-
Saito, T.1
Sherman, G.J.2
Kurokohchi, K.3
Guo, Z.P.4
Donets, M.5
Yu, M.Y.6
Berzofsky, J.A.7
Akatsuka, T.8
Feinstone, S.M.9
-
27
-
-
0042909334
-
Generating conditional mouse mutants via tetracycline-controlled gene expression
-
Schonig K, Bujard H. 2003. Generating conditional mouse mutants via tetracycline-controlled gene expression. Methods Mol Biol 209:69-104.
-
(2003)
Methods Mol Biol
, vol.209
, pp. 69-104
-
-
Schonig, K.1
Bujard, H.2
-
29
-
-
0028217613
-
The 5′ flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice
-
Talbot D, Descombes P, Schibler U. 1994. The 5′ flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice. Nucleic Acids Res 22:756-766.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 756-766
-
-
Talbot, D.1
Descombes, P.2
Schibler, U.3
-
30
-
-
0029971032
-
Expression and immune response to hepatitis C virus core DNA-based vaccine constructs
-
Tokushige K, Wakita T, Pachuk C, Moradpour D, Weiner DB, Zurawski VR, Jr., Wands JR. 1996. Expression and immune response to hepatitis C virus core DNA-based vaccine constructs. Hepatology 24:14-20.
-
(1996)
Hepatology
, vol.24
, pp. 14-20
-
-
Tokushige, K.1
Wakita, T.2
Pachuk, C.3
Moradpour, D.4
Weiner, D.B.5
Zurawski Jr., V.R.6
Wands, J.R.7
-
31
-
-
12244276796
-
Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein
-
Tsutsumi T, Suzuki T, Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Matsuura Y, Kimura S, Koike K, Miyamura T. 2002. Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein. Virology 304:415-424.
-
(2002)
Virology
, vol.304
, pp. 415-424
-
-
Tsutsumi, T.1
Suzuki, T.2
Moriya, K.3
Yotsuyanagi, H.4
Shintani, Y.5
Fujie, H.6
Matsuura, Y.7
Kimura, S.8
Koike, K.9
Miyamura, T.10
-
32
-
-
0141866947
-
Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice
-
Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T. 2003. Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice. Hepatology 38:820-828.
-
(2003)
Hepatology
, vol.38
, pp. 820-828
-
-
Tsutsumi, T.1
Suzuki, T.2
Moriya, K.3
Shintani, Y.4
Fujie, H.5
Miyoshi, H.6
Matsuura, Y.7
Koike, K.8
Miyamura, T.9
-
33
-
-
0032502731
-
Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system
-
Wakita T, Taya C, Katsume A, Kato J, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Kohara M. 1998. Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system. J Biol Chem 273:9001-9006.
-
(1998)
J Biol Chem
, vol.273
, pp. 9001-9006
-
-
Wakita, T.1
Taya, C.2
Katsume, A.3
Kato, J.4
Yonekawa, H.5
Kanegae, Y.6
Saito, I.7
Hayashi, Y.8
Koike, M.9
Kohara, M.10
-
34
-
-
0033799920
-
Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system
-
Wakita T, Katsume A, Kato J, Taya C, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Miyamoto M, Hiasa Y, Kohara M. 2000. Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system. J Med Virol 62:308-317.
-
(2000)
J Med Virol
, vol.62
, pp. 308-317
-
-
Wakita, T.1
Katsume, A.2
Kato, J.3
Taya, C.4
Yonekawa, H.5
Kanegae, Y.6
Saito, I.7
Hayashi, Y.8
Koike, M.9
Miyamoto, M.10
Hiasa, Y.11
Kohara, M.12
-
35
-
-
0030740520
-
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
-
Yanagi M, Purcell RH, Emerson SU, Bukh J. 1997. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee. Proc Natl Acad Sci USA 94:8738-8743.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8738-8743
-
-
Yanagi, M.1
Purcell, R.H.2
Emerson, S.U.3
Bukh, J.4
-
36
-
-
0029816480
-
Conditional transgene expression in the heart
-
Yu Z, Redfern CS, Fishman GI. 1996. Conditional transgene expression in the heart. Circ Res 79:691-697.
-
(1996)
Circ Res
, vol.79
, pp. 691-697
-
-
Yu, Z.1
Redfern, C.S.2
Fishman, G.I.3
|