메뉴 건너뛰기




Volumn 41, Issue 7, 2007, Pages 788-797

Chronic hypoxia promotes an aggressive phenotype in rat prostate cancer cells

Author keywords

Chronic hypoxia; HIF 1 ; MMPs; NF B; VEGF

Indexed keywords

GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MATRIGEL; VASCULOTROPIN;

EID: 34347266205     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760701361531     Document Type: Article
Times cited : (38)

References (46)
  • 1
    • 0035855668 scopus 로고    scopus 로고
    • Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
    • Suzuki, H., Tomida, A. and Tsuruo, T. (2001) Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene, 20, pp. 5779-5788.
    • (2001) Oncogene , vol.20 , pp. 5779-5788
    • Suzuki, H.1    Tomida, A.2    Tsuruo, T.3
  • 3
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter, HM, Ratcliffe, PJ, Watson, P., Greenberg, AH and Harris, AL (2001) HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res, 61, pp. 6669-6673.
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 5
    • 0034647933 scopus 로고    scopus 로고
    • Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
    • Haddad, JJ, Olver, RE and Land, SC (2000) Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells. J Biol Chem, 275, pp. 21130-21139.
    • (2000) J Biol Chem , vol.275 , pp. 21130-21139
    • Haddad, J.J.1    Olver, R.E.2    Land, S.C.3
  • 6
    • 0036830469 scopus 로고    scopus 로고
    • Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes
    • Michiels, C., Minet, E., Mottet, D. and Raes, M. (2002) Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes. Free Radic Biol Med, 33, pp. 1231-1242.
    • (2002) Free Radic Biol Med , vol.33 , pp. 1231-1242
    • Michiels, C.1    Minet, E.2    Mottet, D.3    Raes, M.4
  • 8
    • 0031034814 scopus 로고    scopus 로고
    • Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells
    • Schmedtje Jr., JF, Ji, YS, Liu, WL, DuBois, RN and Runge, MS (1997) Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells. J Biol Chem, 272, pp. 601-608.
    • (1997) J Biol Chem , vol.272 , pp. 601-608
    • Schmedtje Jr., J.F.1    Ji, Y.S.2    Liu, W.L.3    DuBois, R.N.4    Runge, M.S.5
  • 9
    • 0028032360 scopus 로고
    • Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2)
    • Koong, AC, Chen, EY, Mivechi, NF, Denko, NC, Stambrook, P. and Giaccia, AJ (1994) Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Res, 54, pp. 5273-5279.
    • (1994) Cancer Res , vol.54 , pp. 5273-5279
    • Koong, A.C.1    Chen, E.Y.2    Mivechi, N.F.3    Denko, N.C.4    Stambrook, P.5    Giaccia, A.J.6
  • 13
    • 0034641615 scopus 로고    scopus 로고
    • Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
    • Kamura, T., Sato, S., Iwai, K., Czyzyk-Krzeska, M., Conaway, RC and Conaway, JW (2000) Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. Proc Natl Acad Sci USA, 97, pp. 10430-10435.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10430-10435
    • Kamura, T.1    Sato, S.2    Iwai, K.3    Czyzyk-Krzeska, M.4    Conaway, R.C.5    Conaway, J.W.6
  • 14
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
    • Tanimoto, K., Makino, Y., Pereira, T. and Poellinger, L. (2000) Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. EMBO J, 19, pp. 4298-4309.
    • (2000) EMBO J , vol.19 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 15
    • 0033776536 scopus 로고    scopus 로고
    • Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
    • Ohh, M., Park, CW, Ivan, M., Hoffman, MA, Kim, TY, Huang, LE, Pavletich, N., Chau, V. and Kaelin, WG (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol, 2, pp. 423-427.
    • (2000) Nat Cell Biol , vol.2 , pp. 423-427
    • Ohh, M.1    Park, C.W.2    Ivan, M.3    Hoffman, M.A.4    Kim, T.Y.5    Huang, L.E.6    Pavletich, N.7    Chau, V.8    Kaelin, W.G.9
  • 16
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation
    • Verma, IM, Stevenson, JK, Schwarz, EM, Van Antwerp, D. and Miyamoto, S. (1995) Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation. Genes Dev, 9, pp. 2723-2735.
    • (1995) Genes Dev , vol.9 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 19
    • 0037470172 scopus 로고    scopus 로고
    • Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein
    • Jung, YJ, Isaacs, JS, Lee, S., Trepel, J. and Neckers, L. (2003) Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein. J Biol Chem, 278, pp. 7445-7452.
    • (2003) J Biol Chem , vol.278 , pp. 7445-7452
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 22
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang, S., Pettaway, CA, Uehara, H., Bucana, CD and Fidler, IJ (2001) Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene, 20, pp. 4188-4197.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 23
    • 0025230509 scopus 로고
    • Metalloproteinases and their inhibitors in matrix remodeling
    • Matrisian, LM (1990) Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet, 6, pp. 121-125.
    • (1990) Trends Genet , vol.6 , pp. 121-125
    • Matrisian, L.M.1
  • 24
    • 0028346025 scopus 로고
    • Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells
    • Bernhard, EJ, Gruber, SB and Muschel, RJ (1994) Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc Natl Acad Sci USA, 91, pp. 4293-4297.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4293-4297
    • Bernhard, E.J.1    Gruber, S.B.2    Muschel, R.J.3
  • 25
    • 0027713294 scopus 로고
    • Plasminogen activator and metalloprotease activities of Du-145, PC-3, and 1-LN-PC-3-1A human prostate tumors grown in nude mice: Correlation with tumor invasive behavior
    • Wilson, MJ and Sinha, AA (1993) Plasminogen activator and metalloprotease activities of Du-145, PC-3, and 1-LN-PC-3-1A human prostate tumors grown in nude mice: Correlation with tumor invasive behavior. Cell Mol Biol Res, 39, pp. 751-760.
    • (1993) Cell Mol Biol Res , vol.39 , pp. 751-760
    • Wilson, M.J.1    Sinha, A.A.2
  • 26
    • 0030838465 scopus 로고    scopus 로고
    • Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: Correlation with metastatic behavior in vivo
    • Quax, PH, de Bart, AC, Schalken, JA and Verheijen, JH (1997) Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: Correlation with metastatic behavior in vivo. Prostate, 32, pp. 196-204.
    • (1997) Prostate , vol.32 , pp. 196-204
    • Quax, P.H.1    de Bart, A.C.2    Schalken, J.A.3    Verheijen, J.H.4
  • 27
    • 0025611427 scopus 로고
    • Type IV collagenases in tumor invasion and metastasis
    • Stetler-Stevenson, WG (1990) Type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev, 9, pp. 289-303.
    • (1990) Cancer Metastasis Rev , vol.9 , pp. 289-303
    • Stetler-Stevenson, W.G.1
  • 28
    • 0029926229 scopus 로고    scopus 로고
    • Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences
    • Gum, R., Lengyel, E., Juarez, J., Chen, JH, Sato, H., Seiki, M. and Boyd, D. (1996) Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J Biol Chem, 271, pp. 10672-10680.
    • (1996) J Biol Chem , vol.271 , pp. 10672-10680
    • Gum, R.1    Lengyel, E.2    Juarez, J.3    Chen, J.H.4    Sato, H.5    Seiki, M.6    Boyd, D.7
  • 29
    • 0037699018 scopus 로고    scopus 로고
    • Overexpression of vimentin: Role in the invasive phenotype in an androgen-independent model of prostate cancer
    • Singh, S., Sadacharan, S., Belldegrun, A., Persad, S. and Singh, G. (2003) Overexpression of vimentin: Role in the invasive phenotype in an androgen-independent model of prostate cancer. Cancer Res, 63, pp. 2306-2311.
    • (2003) Cancer Res , vol.63 , pp. 2306-2311
    • Singh, S.1    Sadacharan, S.2    Belldegrun, A.3    Persad, S.4    Singh, G.5
  • 30
    • 0032910693 scopus 로고    scopus 로고
    • Role for NF-kappa B in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells
    • Cazals, V., Nabeyrat, E., Corroyer, S., de Keyzer, Y. and Clement, A. (1999) Role for NF-kappa B in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells. Biochim Biophys Acta, 1448, pp. 349-362.
    • (1999) Biochim Biophys Acta , vol.1448 , pp. 349-362
    • Cazals, V.1    Nabeyrat, E.2    Corroyer, S.3    de Keyzer, Y.4    Clement, A.5
  • 31
    • 0028805375 scopus 로고
    • Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences
    • Ebert, BL, Firth, JD and Ratcliffe, PJ (1995) Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences. J Biol Chem, 270, pp. 29083-29089.
    • (1995) J Biol Chem , vol.270 , pp. 29083-29089
    • Ebert, B.L.1    Firth, J.D.2    Ratcliffe, P.J.3
  • 32
    • 0027772521 scopus 로고
    • Growth factors, mitogens, oncogenes and the regulation of glucose transport
    • Merrall, NW, Plevin, R. and Gould, GW (1993) Growth factors, mitogens, oncogenes and the regulation of glucose transport. Cell Signal, 5, pp. 667-675.
    • (1993) Cell Signal , vol.5 , pp. 667-675
    • Merrall, N.W.1    Plevin, R.2    Gould, G.W.3
  • 33
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe, JA, Jiang, BH, Iyer, NV, Agani, F., Leung, SW, Koos, RD and Semenza, GL (1996) Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol, 16, pp. 4604-4613.
    • (1996) Mol Cell Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3    Agani, F.4    Leung, S.W.5    Koos, R.D.6    Semenza, G.L.7
  • 34
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol, 15, pp. 551-578.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 35
    • 0043234256 scopus 로고    scopus 로고
    • Regulation of HIF-1alpha protein level during hypoxic conditions by the PI3K/AKT/GSK3beta pathway in HepG2 cells
    • Mottet, D., Dumont, V., Deccache, Y., Demazy, C., Ninane, N., Raes, M. and Michiels, C. (2003) Regulation of HIF-1alpha protein level during hypoxic conditions by the PI3K/AKT/GSK3beta pathway in HepG2 cells. J Biol Chem, 278, pp. 31277-31285.
    • (2003) J Biol Chem , vol.278 , pp. 31277-31285
    • Mottet, D.1    Dumont, V.2    Deccache, Y.3    Demazy, C.4    Ninane, N.5    Raes, M.6    Michiels, C.7
  • 36
    • 0037177867 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription
    • Arsham, AM, Plas, DR, Thompson, CB and Simon, MC (2002) Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. J Biol Chem, 277, pp. 15162-15170.
    • (2002) J Biol Chem , vol.277 , pp. 15162-15170
    • Arsham, A.M.1    Plas, D.R.2    Thompson, C.B.3    Simon, M.C.4
  • 37
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • Sang, N., Stiehl, DP, Bohensky, J., Leshchinsky, I., Srinivas, V. and Caro, J. (2003) MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem, 278, pp. 14013-14019.
    • (2003) J Biol Chem , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 39
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang, BH, Rue, E., Wang, GL, Roe, R. and Semenza, GL (1996) Dimerization DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem, 271, pp. 17771-17778.
    • (1996) J Biol Chem , vol.271 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 40
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda, E., Achen, MG, Breier, G. and Risau, W. (1995) Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem, 270, pp. 19761-19766.
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 41
    • 0029795584 scopus 로고    scopus 로고
    • Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel Lindau protein
    • Levy, AP, Levy, NS and Goldberg, MA (1996) Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel Lindau protein. J Biol Chem, 271, pp. 25492-25497.
    • (1996) J Biol Chem , vol.271 , pp. 25492-25497
    • Levy, A.P.1    Levy, N.S.2    Goldberg, M.A.3
  • 42
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • Schreck, R., Rieber, P. and Baeuerle, PA (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J, 10, pp. 2247-2258.
    • (1991) EMBO J , vol.10 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 43
    • 0035933716 scopus 로고    scopus 로고
    • Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway
    • Srinivas, V., Leshchinsky, I., Sang, N., King, MP, Minchenko, A. and Caro, J. (2001) Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway. J Biol Chem, 276, pp. 21995-21998.
    • (2001) J Biol Chem , vol.276 , pp. 21995-21998
    • Srinivas, V.1    Leshchinsky, I.2    Sang, N.3    King, M.P.4    Minchenko, A.5    Caro, J.6
  • 44
    • 0023025173 scopus 로고
    • Establishment and characterization of seven dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers
    • Isaacs, JT, Isaacs, WB, Feitz, WF and Scheres, J. (1986) Establishment and characterization of seven dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers. Prostate, 9, pp. 261-281.
    • (1986) Prostate , vol.9 , pp. 261-281
    • Isaacs, J.T.1    Isaacs, W.B.2    Feitz, W.F.3    Scheres, J.4
  • 46
    • 0032570760 scopus 로고    scopus 로고
    • Studies of type IV collagenase regulation by hypoxia
    • Himelstein, BP and Koch, CJ (1998) Studies of type IV collagenase regulation by hypoxia. Cancer Lett, 124, pp. 127-133.
    • (1998) Cancer Lett , vol.124 , pp. 127-133
    • Himelstein, B.P.1    Koch, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.