Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis

Journal of Neuroimmunology

Volumn 187, Issue 1-2, 2007, Pages 61-73

  Kleiter, Ingo ^a   Pedré, Xiomara ^a   Mueller, André M ^a   Poeschl, Peter ^a   Couillard Despres, Sebastien ^a   Spruss, Thilo ^a   Bogdahn, Ulrich ^a   Giegerich, Gerhard ^a,b   Steinbrecher, Andreas ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b Entelechon GmbH   (Germany)

Author keywords

Antisense oligonucleotide; Autoimmunity; Inflammation; Smad7; T cell; TGF beta

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BRAIN PROTEIN; MESSENGER RNA; PHOSPHOROTHIOIC ACID; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL LINE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EX VIVO STUDY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; KIDNEY CELL; LIVER CELL; LYMPH NODE; LYMPH NODE CELL; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPINAL CORD; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION REGULATION; LYMPHOCYTES; MICE; MICE, INBRED STRAINS; OLIGONUCLEOTIDES, ANTISENSE; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; THIONUCLEOTIDES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 34347238571     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.04.014     Document Type: Article

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