-
1
-
-
0000358195
-
Case of hypertrophy of the spleen and liver, in which death took place from suppuration of the blood
-
Bennett JH: Case of hypertrophy of the spleen and liver, in which death took place from suppuration of the blood. Edinburgh Medical and Surgical Journal 1845; 64: 413-423.
-
(1845)
Edinburgh Medical and Surgical Journal
, vol.64
, pp. 413-423
-
-
Bennett, J.H.1
-
2
-
-
0000358194
-
Case of disease of the spleen, in which death took place in consequence of the presence of purulent matter in the blood
-
Cragie D: Case of disease of the spleen, in which death took place in consequence of the presence of purulent matter in the blood. Edinburgh Medical and Surgical Journal 1845; 64: 400-413.
-
(1845)
Edinburgh Medical and Surgical Journal
, vol.64
, pp. 400-413
-
-
Cragie, D.1
-
3
-
-
0000690351
-
Weisses Blut
-
Virchow R: Weisses Blut. Froriep's Notizen 1845; 36: 151-156.
-
(1845)
Froriep's Notizen
, vol.36
, pp. 151-156
-
-
Virchow, R.1
-
5
-
-
0000286732
-
Minute chromosome in human chrnic granulocytic leukemia
-
Nowell PC, Hungerford DAA: minute chromosome in human chrnic granulocytic leukemia. Science 1960; 132: 1497.
-
(1960)
Science
, vol.132
, pp. 1497
-
-
Nowell, P.C.1
Hungerford, D.A.A.2
-
6
-
-
0015694748
-
A new consistent chromosomal abnormality in chrnic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley JD: A new consistent chromosomal abnormality in chrnic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining. Nature 1973; 243: 290-293.
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.D.1
-
7
-
-
0021346853
-
Philaderphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
-
Groffen J, Stephenson JR, Heinterkamp N, De Klein A, Bartram CR, Grosveld G: Philaderphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93-99.
-
(1984)
Cell
, vol.36
, pp. 93-99
-
-
Groffen, J.1
Stephenson, J.R.2
Heinterkamp, N.3
De Klein, A.4
Bartram, C.R.5
Grosveld, G.6
-
8
-
-
0021802841
-
Fused transcript of abl and bcr genes in chrnic myelogenous leukemia
-
Shtivelman E, Lifshitz B, Gale RP, Canaani E: Fused transcript of abl and bcr genes in chrnic myelogenous leukemia. Nature 1985; 315: 550-554.
-
(1985)
Nature
, vol.315
, pp. 550-554
-
-
Shtivelman, E.1
Lifshitz, B.2
Gale, R.P.3
Canaani, E.4
-
10
-
-
0035174344
-
The SH2 domain of Bcr-Abl is not required to induce a murine myeloproliferative disease; however, SH2 signaling influences disease latency and phenotype
-
Zhang X, Rong R, Hao SX, Pear WS, Ren R: The SH2 domain of Bcr-Abl is not required to induce a murine myeloproliferative disease; however, SH2 signaling influences disease latency and phenotype. Blood 2001; 97: 277-287.
-
(2001)
Blood
, vol.97
, pp. 277-287
-
-
Zhang, X.1
Rong, R.2
Hao, S.X.3
Pear, W.S.4
Ren, R.5
-
11
-
-
0032841181
-
Growth factor independence and BCR/ABL transformation: Promise and pitfalls of murine model systems and assays
-
Ghaffari S, Daley GQ, Lodish HF: Growth factor independence and BCR/ABL transformation: promise and pitfalls of murine model systems and assays. Leukemia 1999; 13: 1200-1206.
-
(1999)
Leukemia
, vol.13
, pp. 1200-1206
-
-
Ghaffari, S.1
Daley, G.Q.2
Lodish, H.F.3
-
12
-
-
0025766195
-
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner
-
Pendergast AM, Muller AJ, Havlik MH, Maru Y, Witte ON: BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. Cell 1991; 66: 161-171.
-
(1991)
Cell
, vol.66
, pp. 161-171
-
-
Pendergast, A.M.1
Muller, A.J.2
Havlik, M.H.3
Maru, Y.4
Witte, O.N.5
-
13
-
-
0031459864
-
dok a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
-
dok a constitutively tyrosine-phosphorylated , GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 1997; 88: 197-204.
-
(1997)
Cell
, vol.88
, pp. 197-204
-
-
Carpino, N.1
Wisniewski, D.2
Strife, A.3
-
14
-
-
0030917924
-
Interactions of CBL with BCR-ABL and CRKL in BCR-ABL-transformed myeloid cells
-
Bhat A, Kolibaba K, Oda T, Ohno-Jones S, Heaney C, Druker BJ: Interactions of CBL with BCR-ABL and CRKL in BCR-ABL-transformed myeloid cells. J Biol Chem 1997; 272: 16170-16175.
-
(1997)
J Biol Chem
, vol.272
, pp. 16170-16175
-
-
Bhat, A.1
Kolibaba, K.2
Oda, T.3
Ohno-Jones, S.4
Heaney, C.5
Druker, B.J.6
-
15
-
-
0035166003
-
The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase
-
Roumiantsev S, de Aos IE, Varticovski L, Ilaria R, Van Etten RA: The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase. Blood 2001; 97: 4-13.
-
(2001)
Blood
, vol.97
, pp. 4-13
-
-
Roumiantsev, S.1
De Aos, I.E.2
Varticovski, L.3
Ilaria, R.4
Van Etten, R.A.5
-
16
-
-
0034641709
-
Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity
-
Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc Natl Acad Sci USA 2000; 97: 10538-10543.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10538-10543
-
-
Jiang, Y.1
Zhao, R.C.H.2
Verfaillie, C.M.3
-
17
-
-
0028256425
-
Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
-
Bedi A, Zehnbauer BA, Barber JP, Sharkis SJ, Jones RJ: Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 1994; 83: 2038-2044.
-
(1994)
Blood
, vol.83
, pp. 2038-2044
-
-
Bedi, A.1
Zehnbauer, B.A.2
Barber, J.P.3
Sharkis, S.J.4
Jones, R.J.5
-
19
-
-
0026608119
-
Initiation of dysregulated growth of multipotent progenitor cells by bcr-abl in vitro
-
Gishizky ML, Witte ON: Initiation of dysregulated growth of multipotent progenitor cells by bcr-abl in vitro. Science 1992; 256: 836-839.
-
(1992)
Science
, vol.256
, pp. 836-839
-
-
Gishizky, M.L.1
Witte, O.N.2
-
20
-
-
0033614446
-
Chronic myeloid leukemia
-
Sawyers CL: Chronic myeloid leukemia. N Engl J Med 1999; 340: 1330-1340.
-
(1999)
N Engl J Med
, vol.340
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
21
-
-
0030725775
-
The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates Gl-to-S phase transition in hematopoietic cells
-
Cortez D, Reuther G, Pendergast AM: The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates Gl-to-S phase transition in hematopoietic cells. Oncogene 1997; 15: 2333-2342.
-
(1997)
Oncogene
, vol.15
, pp. 2333-2342
-
-
Cortez, D.1
Reuther, G.2
Pendergast, A.M.3
-
22
-
-
0027368352
-
BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein
-
Pendergast AM, Quilliam LA, Cripe LD, et al.: BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell 1993; 75: 175-185.
-
(1993)
Cell
, vol.75
, pp. 175-185
-
-
Pendergast, A.M.1
Quilliam, L.A.2
Cripe, L.D.3
-
23
-
-
0030710188
-
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
-
Skorski T, Bellacosa A, Nieborowska-Skorska M, et al.: Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J 1997; 16: 6151-6161.
-
(1997)
EMBO J
, vol.16
, pp. 6151-6161
-
-
Skorski, T.1
Bellacosa, A.2
Nieborowska-Skorska, M.3
-
25
-
-
0025209916
-
Acute leukaemia in bcr/abl transgenic mice
-
Heisterkamp N, Jenster G, ten Hoeve J, Zovich D, Pattengale PK, Goffen J: Acute leukaemia in bcr/abl transgenic mice. Nature 1990; 344: 251-253.
-
(1990)
Nature
, vol.344
, pp. 251-253
-
-
Heisterkamp, N.1
Jenster, G.2
Ten Hoeve, J.3
Zovich, D.4
Pattengale, P.K.5
Goffen, J.6
-
26
-
-
0032533257
-
Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow
-
Pear WS, Miller JP, Xu L, et al.: Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow. Blood 1998; 92: 3780-3792.
-
(1998)
Blood
, vol.92
, pp. 3780-3792
-
-
Pear, W.S.1
Miller, J.P.2
Xu, L.3
-
27
-
-
0032533620
-
Bcr-Abl Efficiently Induces a Myeloproliferative Disease and Production of Excess Interleukin-3 and Granulocyte-Macrophage Colony-Stimulating Factor in Mice: A Novel Model for Chronic Myelogenous Leukemia
-
Zhang X, Ren R: Bcr-Abl Efficiently Induces a Myeloproliferative Disease and Production of Excess Interleukin-3 and Granulocyte-Macrophage Colony-Stimulating Factor in Mice: A Novel Model for Chronic Myelogenous Leukemia. Blood 1998; 92: 3829-3840.
-
(1998)
Blood
, vol.92
, pp. 3829-3840
-
-
Zhang, X.1
Ren, R.2
-
28
-
-
0033519238
-
The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity
-
Li S, Ilaria RJ, Million RP, Daley GQ, Van Etten RA: The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. J Exp Med 1999; 189: 1399-1412.
-
(1999)
J Exp Med
, vol.189
, pp. 1399-1412
-
-
Li, S.1
Ilaria, R.J.2
Million, R.P.3
Daley, G.Q.4
Van Etten, R.A.5
-
29
-
-
0030221263
-
Normal and leukemic human stem cells assayed in SCID mice
-
Dick JE: Normal and leukemic human stem cells assayed in SCID mice. Semin Immunol 1996; 8: 197-206.
-
(1996)
Semin Immunol
, vol.8
, pp. 197-206
-
-
Dick, J.E.1
-
30
-
-
0029826591
-
Phenotype and function of human hematopoietic cells engrafting immune- deficient CB 17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells
-
Pflumio F, Izac B, Katz A, Shultz LD, Vainchenker W, Coulombel L: Phenotype and function of human hematopoietic cells engrafting immune- deficient CB 17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells. Blood 1996; 88: 3731-3740.
-
(1996)
Blood
, vol.88
, pp. 3731-3740
-
-
Pflumio, F.1
Izac, B.2
Katz, A.3
Shultz, L.D.4
Vainchenker, W.5
Coulombel, L.6
-
31
-
-
0030925298
-
Kinetic Evidence of the Regeneration of Multilineage Hematopoiesis from Primitive Cells in Normal Human Bone Marrow Transplanted into Immunodeficient Mice
-
Cashman JD, Lapidot T, Wang JCY, et al.: Kinetic Evidence of the Regeneration of Multilineage Hematopoiesis From Primitive Cells in Normal Human Bone Marrow Transplanted Into Immunodeficient Mice. Blood 1997; 89: 4307-4316.
-
(1997)
Blood
, vol.89
, pp. 4307-4316
-
-
Cashman, J.D.1
Lapidot, T.2
Wang, J.C.Y.3
-
32
-
-
13344262695
-
Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis
-
Sirard C, Lapidot T, Vormoor J, et al.: Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood 1996; 87: 1539-1548.
-
(1996)
Blood
, vol.87
, pp. 1539-1548
-
-
Sirard, C.1
Lapidot, T.2
Vormoor, J.3
-
33
-
-
0032529306
-
The Kinetics and Extent of Engraftment of Chronic Myelogenous Leukemia Cells in Non-Obese Diabetic/Severe Combined Immunodeficiency Mice Reflect the Phase of the Donor's Disease: An in vivo Model of Chronic Myelogenous Leukemia Biology
-
Dazzi F, Capelli D, Hesserjian R, et al.: The Kinetics and Extent of Engraftment of Chronic Myelogenous Leukemia Cells in Non-Obese Diabetic/Severe Combined Immunodeficiency Mice Reflect the Phase of the Donor's Disease: An In vivo Model of Chronic Myelogenous Leukemia Biology. Blood 1998; 92: 1390-1396.
-
(1998)
Blood
, vol.92
, pp. 1390-1396
-
-
Dazzi, F.1
Capelli, D.2
Hesserjian, R.3
-
35
-
-
0035344668
-
Models of chronic myeloid leukemia
-
Van Etten RA: Models of chronic myeloid leukemia. Curr Oncol Rep 2001; 3: 228-237.
-
(2001)
Curr Oncol Rep
, vol.3
, pp. 228-237
-
-
Van Etten, R.A.1
-
36
-
-
0026362729
-
Human bcr-abl gene has a lethal effect on embryogenesis
-
Heisterkamp N, Jenster G, Kioussis D, Pattengale PK, Goffen J: Human bcr-abl gene has a lethal effect on embryogenesis. Transgenic Res 1991; 1: 45-53.
-
(1991)
Transgenic Res
, vol.1
, pp. 45-53
-
-
Heisterkamp, N.1
Jenster, G.2
Kioussis, D.3
Pattengale, P.K.4
Goffen, J.5
-
38
-
-
0038240346
-
Myeloproliferative disease in transgenic mice expressing P230 Bcr/Abl: Longer disease latency, thrombocytosis, and mild leukocytosis
-
Inokuchi K, Dan K, Takatori M, et al.: Myeloproliferative disease in transgenic mice expressing P230 Bcr/Abl: longer disease latency, thrombocytosis, and mild leukocytosis. Blood 2003; 102: 320-322.
-
(2003)
Blood
, vol.102
, pp. 320-322
-
-
Inokuchi, K.1
Dan, K.2
Takatori, M.3
-
40
-
-
0142183447
-
Inducible expression of BCR/ABL using human CD 34 regulatory elements results in a megakaryocytic myeloproliferative syndrome
-
Huettner CS, Koschmieder S, Iwasaki H, et al.: Inducible expression of BCR/ABL using human CD 34 regulatory elements results in a megakaryocytic myeloproliferative syndrome. Blood 2003; 102: 3363-3370.
-
(2003)
Blood
, vol.102
, pp. 3363-3370
-
-
Huettner, C.S.1
Koschmieder, S.2
Iwasaki, H.3
-
41
-
-
19944426030
-
Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis
-
Koschmieder S, Gottgens B, Zhang P, et al.: Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis. Blood 2005; 105: 324-334.
-
(2005)
Blood
, vol.105
, pp. 324-334
-
-
Koschmieder, S.1
Gottgens, B.2
Zhang, P.3
-
42
-
-
0036569823
-
Neutrophilic-chronic myeloid leukemia: Low levels of p230 BCR/ABL mRNA and undetectable BCR/ABL protein may predict an indolent course
-
Verstovsek S, Lin H, Kantarjian H, et al.: Neutrophilic-chronic myeloid leukemia: low levels of p230 BCR/ABL mRNA and undetectable BCR/ABL protein may predict an indolent course. Cancer 2002; 94: 2416-2425.
-
(2002)
Cancer
, vol.94
, pp. 2416-2425
-
-
Verstovsek, S.1
Lin, H.2
Kantarjian, H.3
-
43
-
-
0029976933
-
Elevated platelet count features the variant type of BCR/ABL junction in chronic myelogenous leukaemia
-
Yamagata T, Mitani K, Kanda Y, Yazaki Y, Hirai H: Elevated platelet count features the variant type of BCR/ABL junction in chronic myelogenous leukaemia. Br J Haematol 1996; 94: 370-372.
-
(1996)
Br J Haematol
, vol.94
, pp. 370-372
-
-
Yamagata, T.1
Mitani, K.2
Kanda, Y.3
Yazaki, Y.4
Hirai, H.5
-
44
-
-
0035166003
-
The Src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase
-
Roumiantsev S, de Aos I, Varticovski L, Ilaria RL, Van Etten RA: The Src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase. Blood 2001; 97: 4-13.
-
(2001)
Blood
, vol.97
, pp. 4-13
-
-
Roumiantsev, S.1
De Aos, I.2
Varticovski, L.3
Ilaria, R.L.4
Van Etten, R.A.5
-
45
-
-
0036280235
-
Bcb-Abl variants: Biological and clinical aspects
-
Advani AS, Pendergast AM: Bcb-Abl variants: biological and clinical aspects. Leukem Res 2002; 26: 713-720.
-
(2002)
Leukem Res
, vol.26
, pp. 713-720
-
-
Advani, A.S.1
Pendergast, A.M.2
-
46
-
-
0029060662
-
Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein
-
Wada H, Mizutani S, Nishimura J, et al.: Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein. Cancer Res 1995; 55: 3192-3196.
-
(1995)
Cancer Res
, vol.55
, pp. 3192-3196
-
-
Wada, H.1
Mizutani, S.2
Nishimura, J.3
-
47
-
-
0025873083
-
Bcr encodes a GTPase-activating protein for p21rac
-
Diekmann D, Brill S, Garrett MD, et al.: Bcr encodes a GTPase-activating protein for p21rac. Nature 1991; 351: 400-402.
-
(1991)
Nature
, vol.351
, pp. 400-402
-
-
Diekmann, D.1
Brill, S.2
Garrett, M.D.3
-
48
-
-
0029348008
-
Abl tyrosine protein kinase
-
Laneuville P: Abl tyrosine protein kinase. Semin Immunol 1995; 7: 255-266.
-
(1995)
Semin Immunol
, vol.7
, pp. 255-266
-
-
Laneuville, P.1
-
49
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, et al.: Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 2004; 36: 453-461.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
-
50
-
-
0029816460
-
The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
-
Melo JV: The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood 1996; 88: 2375-2384.
-
(1996)
Blood
, vol.88
, pp. 2375-2384
-
-
Melo, J.V.1
-
51
-
-
0023142769
-
A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukemia
-
Kurzrock R, Shtalrid M, Romero P, et al.: A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukemia. Nature 1987; 325: 631-635.
-
(1987)
Nature
, vol.325
, pp. 631-635
-
-
Kurzrock, R.1
Shtalrid, M.2
Romero, P.3
-
52
-
-
0023105320
-
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukemia
-
Chan L, Karhi KK, Rayter SI, et al.: A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukemia. Nature 1987; 325: 635-637.
-
(1987)
Nature
, vol.325
, pp. 635-637
-
-
Chan, L.1
Karhi, K.K.2
Rayter, S.I.3
-
53
-
-
0034192222
-
Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases
-
Quackenbush RQ, Reuther GW, Miller JP, Courtney KD, Pear WS, Pendergast AM: Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases. Blood 2000; 95: 2913-2921.
-
(2000)
Blood
, vol.95
, pp. 2913-2921
-
-
Quackenbush, R.Q.1
Reuther, G.W.2
Miller, J.P.3
Courtney, K.D.4
Pear, W.S.5
Pendergast, A.M.6
-
54
-
-
10144254429
-
Neutrophilic-chronic myeloid leukemia: A distinct disease with a specific molecular marker BCR/ABL with C3/A2 junction
-
Pane F, Friger F, Sindona M, et al.: Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker BCR/ABL with C3/A2 junction. Blood 1996; 88: 2410-2414.
-
(1996)
Blood
, vol.88
, pp. 2410-2414
-
-
Pane, F.1
Friger, F.2
Sindona, M.3
-
55
-
-
0024551255
-
Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells
-
McLaughlin J, Chianese E, Witte ON: Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells. Mol Cell Biol 1989; 9: 1866-1874.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1866-1874
-
-
McLaughlin, J.1
Chianese, E.2
Witte, O.N.3
-
56
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
Lugo TG, Pendergast AM, Muller AJ, Witte ON: Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 1990; 247: 1079-1082.
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
57
-
-
0029845079
-
p210 BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines
-
Okuda K, Golub TR, Gilliland DG, Griffin JD: p210 BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines. Oncogene 1996; 13: 1147-1152.
-
(1996)
Oncogene
, vol.13
, pp. 1147-1152
-
-
Okuda, K.1
Golub, T.R.2
Gilliland, D.G.3
Griffin, J.D.4
-
58
-
-
0024425981
-
Rac, a novel ras-related family of proteins that are botulinum toxin substrates
-
Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R: Rac, a novel ras-related family of proteins that are botulinum toxin substrates. J Biol Chem 1989; 264: 16378-16382.
-
(1989)
J Biol Chem
, vol.264
, pp. 16378-16382
-
-
Didsbury, J.1
Weber, R.F.2
Bokoch, G.M.3
Evans, T.4
Snyderman, R.5
-
59
-
-
0030670095
-
Effect of Bcr sequences on the cellular function of the Bcr-Abl oncoprotein
-
McWhirter JR, Wang JY: Effect of Bcr sequences on the cellular function of the Bcr-Abl oncoprotein. Oncogene 1997; 15: 1625-1634.
-
(1997)
Oncogene
, vol.15
, pp. 1625-1634
-
-
McWhirter, J.R.1
Wang, J.Y.2
-
60
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley AJ, Hall A: The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992; 70: 389-399.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
61
-
-
0023756869
-
The site of the breakpoint within the bcr is a prognostic factor in Philadelphia-positive CML patients
-
Mills KI, Anderson VA, Burns JH, Birnie GD: The site of the breakpoint within the bcr is a prognostic factor in Philadelphia-positive CML patients. Blood 1988; 72: 1237-1241.
-
(1988)
Blood
, vol.72
, pp. 1237-1241
-
-
Mills, K.I.1
Anderson, V.A.2
Burns, J.H.3
Birnie, G.D.4
-
62
-
-
0027236472
-
Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia
-
Fioretos T, Nilsson PG, Aman P, et al.: Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia. Leukemia 1993; 7: 1225-1231.
-
(1993)
Leukemia
, vol.7
, pp. 1225-1231
-
-
Fioretos, T.1
Nilsson, P.G.2
Aman, P.3
-
63
-
-
0028960453
-
Analysis of molecular breakpoint and m-RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: No correlation with clinical features, cytogenetic response, duration of chronic phase, or survival
-
Shepherd P, Suffolk R, Halsey J, Allan N: Analysis of molecular breakpoint and m-RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: no correlation with clinical features, cytogenetic response, duration of chronic phase, or survival. Br J Haematol 1995; 89: 546-554.
-
(1995)
Br J Haematol
, vol.89
, pp. 546-554
-
-
Shepherd, P.1
Suffolk, R.2
Halsey, J.3
Allan, N.4
-
64
-
-
0026345834
-
A possible correlation between the type of bcr-abl hybrid messenger RNA and platelet count in Philadelphia-positive chronic myelogenous leukemia
-
Inokuchi K, Inoue T, Tojo A, et al.: A possible correlation between the type of bcr-abl hybrid messenger RNA and platelet count in Philadelphia-positive chronic myelogenous leukemia. Blood 1991; 78: 3125-3127.
-
(1991)
Blood
, vol.78
, pp. 3125-3127
-
-
Inokuchi, K.1
Inoue, T.2
Tojo, A.3
-
65
-
-
0026411131
-
The relationship between the site of breakpoints within the bcr gene and thrombopoiesis of Philadelphia-positive chronic myelocytic leukemia
-
Inokuchi K, Futaki M, Yamada T, et al.: The relationship between the site of breakpoints within the bcr gene and thrombopoiesis of Philadelphia-positive chronic myelocytic leukemia. Leukemia Research 1991; 15: 1067-1073.
-
(1991)
Leukemia Research
, vol.15
, pp. 1067-1073
-
-
Inokuchi, K.1
Futaki, M.2
Yamada, T.3
-
66
-
-
0033934404
-
The possible influences of B2A2 and B3A2 BCR/ABL protein structure on thrombopoiesis in chronic myeloid leukaemia
-
Perego RA, Costantini M, Cornacchini G, et al.: The possible influences of B2A2 and B3A2 BCR/ABL protein structure on thrombopoiesis in chronic myeloid leukaemia. Eur J Cancer 2000; 36: 1395-1401.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1395-1401
-
-
Perego, R.A.1
Costantini, M.2
Cornacchini, G.3
-
67
-
-
0036282898
-
Younger age and shorter chronic phase in b2a2-positive chronic myeloid leukemia adults with high white blood cell count at diagnosis
-
Martinez-Mancilla M, Gutierrez M, Zafra de la Rosa G, Garcia-Carranca A, Gariglio P, Miranda E: Younger age and shorter chronic phase in b2a2-positive chronic myeloid leukemia adults with high white blood cell count at diagnosis. Haematologica 2002; 87: 666-668.
-
(2002)
Haematologica
, vol.87
, pp. 666-668
-
-
Martinez-Mancilla, M.1
Gutierrez, M.2
Zafra De La Rosa, G.3
Garcia-Carranca, A.4
Gariglio, P.5
Miranda, E.6
-
68
-
-
0027209326
-
Will molecular biology contribute to refine prognosis and to select treatment?
-
The Molecular Biology Committee. Italian Cooperative Study Group on Chronic Myeloid Leukemia
-
Zaccaria A, Martinelli G, Buzzi M, Farabegoli P: Will molecular biology contribute to refine prognosis and to select treatment? The Molecular Biology Committee. Italian Cooperative Study Group on Chronic Myeloid Leukemia. Leuk Lymphoma 1993; 11, Suppl 1: 81-89.
-
(1993)
Leuk Lymphoma
, vol.11
, Issue.1 SUPPL.
, pp. 81-89
-
-
Zaccaria, A.1
Martinelli, G.2
Buzzi, M.3
Farabegoli, P.4
-
69
-
-
0030035440
-
Chronic myeloid leukemia of thrombocythemic onset: A CML subtype with distinct hematological and molecular features?
-
Cervantes F, Colomer D, Vives-Corrons JL, Rozman C, Montserrat E: Chronic myeloid leukemia of thrombocythemic onset: a CML subtype with distinct hematological and molecular features? Leukemia 1996; 10: 1241-1243.
-
(1996)
Leukemia
, vol.10
, pp. 1241-1243
-
-
Cervantes, F.1
Colomer, D.2
Vives-Corrons, J.L.3
Rozman, C.4
Montserrat, E.5
-
70
-
-
0030852332
-
BCR-ABL transcripts in bone marrow aspirates of Philadelphia-negative essential thrombocytopenia patients: Clinical presentation
-
Blickstein D, Aviram A, Luboshitz J, et al.: BCR-ABL transcripts in bone marrow aspirates of Philadelphia-negative essential thrombocytopenia patients: clinical presentation. Blood 1997; 90: 2768-2771.
-
(1997)
Blood
, vol.90
, pp. 2768-2771
-
-
Blickstein, D.1
Aviram, A.2
Luboshitz, J.3
-
71
-
-
0036569823
-
Neutrophilic-chronic myeloid leukemia: Low levels of p230 BCR/ABL mRNA and undetectable p230 BCR/ABL protein may predict an indolent course
-
Verstovsek S, Lin H, Kantarjian H, et al.: Neutrophilic-chronic myeloid leukemia: Low levels of p230 BCR/ABL mRNA and undetectable p230 BCR/ABL protein may predict an indolent course. Cancer 2002; 94: 2416-2425.
-
(2002)
Cancer
, vol.94
, pp. 2416-2425
-
-
Verstovsek, S.1
Lin, H.2
Kantarjian, H.3
-
72
-
-
0037049764
-
BCR/ABL genes and leukemic phenotype: From molecular mechanisms to clinical correlations
-
Pane F, Intrieri M, Quintarelli C, Izzo B, Muccioli GC, Salvatore F: BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical correlations. Oncogene 2002; 21: 8652-8667.
-
(2002)
Oncogene
, vol.21
, pp. 8652-8667
-
-
Pane, F.1
Intrieri, M.2
Quintarelli, C.3
Izzo, B.4
Muccioli, G.C.5
Salvatore, F.6
-
73
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al.: Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996; 2: 561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
74
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger E, Zimmermann J, Mett H, et al.: Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res 1996; 56: 100-104.
-
(1996)
Cancer Res
, vol.56
, pp. 100-104
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
-
75
-
-
0034665713
-
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase
-
Schindler T, Bornmann W, Pellicena P, Miller WT, Clarkson B, Kuriyan J: Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science 2000; 289: 1938-1942.
-
(2000)
Science
, vol.289
, pp. 1938-1942
-
-
Schindler, T.1
Bornmann, W.2
Pellicena, P.3
Miller, W.T.4
Clarkson, B.5
Kuriyan, J.6
-
76
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al.: Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
77
-
-
0036094117
-
Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia
-
Cohen MH, Williams G, Johnson JR, et al.: Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin Cancer Res 2002; 8: 935-942.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 935-942
-
-
Cohen, M.H.1
Williams, G.2
Johnson, J.R.3
-
78
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al.: Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293: 876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
79
-
-
0036566540
-
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI 571) resistance
-
Branford S, Rudzki Z, Walsh S, et al.: High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI 571) resistance. Blood 2002; 99: 3472-3475.
-
(2002)
Blood
, vol.99
, pp. 3472-3475
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
80
-
-
0034161460
-
Induction of resistance to the Abelson inhibitor STI 571 in human leukemic cells through gene amplification
-
Le Coutre P, Tassi E, Varella-Garcia M, et al.: Induction of resistance to the Abelson inhibitor STI 571 in human leukemic cells through gene amplification. Blood 2000; 95: 1758-1766.
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Le Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
-
81
-
-
0036850514
-
Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
-
Hochhaus A, Kreil S, Corbin AS, et al.: Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia 2002; 16: 2190-2196.
-
(2002)
Leukemia
, vol.16
, pp. 2190-2196
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.S.3
-
82
-
-
0034665713
-
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase
-
Schindler T, Bornmann W, Pellicena P, Miller WT, B. Clarkson B, Kuriyan J: Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science 2000; 289: 1938-1942.
-
(2000)
Science
, vol.289
, pp. 1938-1942
-
-
Schindler, T.1
Bornmann, W.2
Pellicena, P.3
Miller, W.T.4
Clarkson, B.5
Kuriyan, J.6
-
83
-
-
13844251975
-
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
-
Weisberg E, Manley PW, Breitenstein W, et al.: Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell 2005; 7: 129-141.
-
(2005)
Cancer Cell
, vol.7
, pp. 129-141
-
-
Weisberg, E.1
Manley, P.W.2
Breitenstein, W.3
-
84
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL: Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 2004; 305: 399-401.
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
85
-
-
13844261144
-
A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance
-
Gumireddy K, Baker SJ, Cosenza SC, et al.: A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance. Proc Natl Acad Sci USA 2005; 102: 1992-1997.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1992-1997
-
-
Gumireddy, K.1
Baker, S.J.2
Cosenza, S.C.3
-
86
-
-
0025614040
-
The location of the Philadelphia chromosomal breakpoint site and prognosis in chronic granulocytic leukemia
-
Tefferi A, Bren GD, Wagner KV, Schaid DJ, Ash RC, Thinbodeau SN: The location of the Philadelphia chromosomal breakpoint site and prognosis in chronic granulocytic leukemia. Leukemia 1990; 4: 839-842.
-
(1990)
Leukemia
, vol.4
, pp. 839-842
-
-
Tefferi, A.1
Bren, G.D.2
Wagner, K.V.3
Schaid, D.J.4
Ash, R.C.5
Thinbodeau, S.N.6
-
87
-
-
0026688906
-
Molecular breakpoints and platelet counts in chrnic myeloid leukemia
-
Shepherd PCA, Bond C, Allan NC: Molecular breakpoints and platelet counts in chrnic myeloid leukemia. Blood 1992; 80: 556-557.
-
(1992)
Blood
, vol.80
, pp. 556-557
-
-
Shepherd, P.C.A.1
Bond, C.2
Allan, N.C.3
-
88
-
-
18344365978
-
Transgenic mouse models of BCR/ABL-positive chronic myelogenous leukemia: A Review
-
Inokuchi K: Transgenic mouse models of BCR/ABL-positive chronic myelogenous leukemia: A Review. Curr Genom 2005; 6: 89-95.
-
(2005)
Curr Genom
, vol.6
, pp. 89-95
-
-
Inokuchi, K.1
-
89
-
-
0027172203
-
The relationship between the type of bcr-abl hybrid messenger RNA and thrombopoiesis in Philadelphia-positive chrnic myelogenous leukemia
-
Inokuchi K, Nomura T: The relationship between the type of bcr-abl hybrid messenger RNA and thrombopoiesis in Philadelphia-positive chrnic myelogenous leukemia. Leukem Lymphom 1993; 10: 9-15.
-
(1993)
Leukem Lymphom
, vol.10
, pp. 9-15
-
-
Inokuchi, K.1
Nomura, T.2
|