Antioxidative and antitumor activity of derivatives of 4-β-amino- 4′-demethylepipodophyllotoxin and their structure-activity relationship

Pharmazie

Volumn 62, Issue 6, 2007, Pages 432-438

  Zhang, Xiao Yu ^a,c   Li, Wen Guang ^a,c   Wu, Yong Jie ^a,c   Tian, Xuan ^b  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c Key Laboratory of Preclinical Study for New Drugs of Gansu Province   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 BETA AMINO 4' DEMETHYLEPIPODOPHYLLOTOXIN; ASCORBIC ACID; EPIPODOPHYLLOTOXIN DERIVATIVE; FERRIC ION; FREE RADICAL; HYDROGEN PEROXIDE; HYDROXYL GROUP; MALONALDEHYDE; NITROBLUE TETRAZOLIUM; OXYGEN; SUPEROXIDE; THIOBARBITURIC ACID; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HEART; HEMOLYSIS; KIDNEY HOMOGENATE; LIVER HOMOGENATE; MALE; NEUTROPHIL; NONHUMAN; RAT; REDUCTION; SPECTROPHOTOMETRY; STRUCTURE ACTIVITY RELATION; TISSUE HOMOGENATE;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL PROLIFERATION; ERYTHROCYTES; FEMALE; HEMOLYSIS; HUMANS; HYDROGEN PEROXIDE; INDICATORS AND REAGENTS; K562 CELLS; LIVER; MALE; MALONDIALDEHYDE; NEUTROPHILS; PODOPHYLLOTOXIN; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 34250855684     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2007.6.6667     Document Type: Article

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