Antioxidative activity of 4-oxy- and 4-hydroxy-nitroxides in tissues and erythrocytes from rats

Acta Pharmacologica Sinica

Volumn 18, Issue 2, 1997, Pages 150-154

  Wu, Yong Jie ^a   Li, Wen Guang ^a   Zhang, Zhen Ming ^b,c   Tian, Xuan ^a  

^a LANZHOU MEDICAL COLLEGE   (China)

^b LANZHOU UNIVERSITY   (China)

^c GANSU PROVINCIAL HOSPITAL   (China)

Author keywords

antioxidants; erythrocytes; free radical scavengers; free radicals; malondialdehyde; neutrophils; nitroxides

Indexed keywords

HYDROGEN PEROXIDE; MALONALDEHYDE; NITROBLUE TETRAZOLIUM; NITROXIDE; NITROXIDE DERIVATIVE; SUPEROXIDE; TEMPOL; TEMPONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ZYMOSAN;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COLORIMETRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ERYTHROCYTE; FEMALE; HEART; HEMOLYSIS; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; NEUTROPHIL; NONHUMAN; RAT; SPECTROPHOTOMETRY; TISSUE HOMOGENATE;

ANIMALS; ANTIOXIDANTS; CYCLIC N-OXIDES; FEMALE; FREE RADICAL SCAVENGERS; HEMOLYSIS; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; SPIN LABELS;

EID: 0030964425     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Zhang JZ, Zhao BL, Zhang QG, editors. Basic theory and application of spin labelling ESR spectrum. 1st ed. Beijing: Science Press, 1987: 34-195.
2. Zheng RL, Liu LS, Swans HM, Zhang ZY, Wei LL. Inhibition of nitroxide free radicals against DNA synthesis of leukemia cells. Sci Sin (B) 1990; (6): 592-6.
3. Anastassopoulou JD, Rakintzis NT. Reaction of OH radicals with 2,2,6,6-tetramethyl-4-piperidinol-1-oxyl (TEMPOL) in aqueous solution. Z Phys Chem Neue Folge 1984; 141: S53-S58.
4. 2+ in rat neutrophils. Acta Pharmacol Sin 1991; 12: 280-4.
5. Tanizaw AH, Sazuka Y, Takino Y. Micro-determination of lipoperoxide in the mouse myocardium by thiobarbituric acid fluorophotometry. Chem Pharm Bull 1981; 29: 2910-4.
6. Baehner RL, Nathan DG. Quantitative nitroblue tetrazolium test in chronic granulomatous disease. N Engl J Med 1968; 278: 971-6.
7. Feng LM, Lin FB, Pan HZ, Zhang ZN, Huang F, Liang XF. The antioxidant action of maltol on the erythrocyte membrane. Chin Pharmacol Bull 1990; 6: 224-8.
8. Tallarida RJ, Murray RB. Manual of pharmacologic calculations with computer programs. 1st ed. New York: Springer, 1981: 14-21.
9. Lu XY. Injury in rat liver mitochondria induced by ascorbic acid and ferrous sulfate. Biochem Biophys 1989; 16: 372-4, 382.
10. DiGregorio KA, Cilento EV, Lants RC. Measurement of superoxide release from single pulmonary alveolar macrophages. Am J Physiol 1987; 252 (6 Pt 1): C677-C683.