α-Synuclein gene expression profile in the retina of vertebrates

Molecular Vision

Volumn 13, Issue , 2007, Pages 949-961

  Martínez Navarrete, Gema C ^a   Martín Nieto, José ^a   Esteve Rudd, Julián ^a   Angulo, Antonia ^a   Cuenca, Nicolás ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MESSENGER RNA; SYNAPTOPHYSIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL POLARITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; GABAERGIC TRANSMISSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOCATION; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; NERVE CELL; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RETINA AMACRINE CELL; RETINA CELL; RETINA CONE; RETINA INNER PLEXIFORM LAYER; RETINA ROD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPSE VESICLE; VERTEBRATE;

ALPHA-SYNUCLEIN; AMACRINE CELLS; ANIMALS; CONES (RETINA); CYTOPLASM; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLYCINE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; PHAGOSOMES; PIGMENT EPITHELIUM OF EYE; PRESYNAPTIC TERMINALS; RETINAL BIPOLAR CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ROD OUTER SEGMENTS; SYNAPTOPHYSIN; TISSUE DISTRIBUTION; VERTEBRATES;

EID: 34250845054     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Ueda K, Fukushima H, Masliah E, Xia Y, Iwai A, Yoshimoto M, Otero DA, Kondo J, Ihara Y, Saitoh T. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci U S A 1993; 90:11282-6.
2. Iwai A, Masliah E, Yoshimoto M, Ge N, Flanagan L, de Silva HA, Kittel A, Saitoh T. The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 1995; 14:467-75.
3. Irizarry MC, Kim TW, McNamara M, Tanzi RE, George JM, Clayton DF, Hyman BT. Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system. J Neuropathol Exp Neurol 1996; 55:889-95.
4. Bayer TA, Jakala P, Hartmann T, Egensperger R, Buslei R, Falkai P, Beyreuther K. Neural expression profile of alpha-synuclein in developing human cortex. Neuroreport 1999; 10:2799-803.
5. Solano SM, Miller DW, Augood SJ, Young AB, Penney JB Jr. Expression of alpha-synuclein, parkin, and ubiquitin carboxyterminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease. Ann Neurol 2000; 47:201-10.
6. Jakes R, Spillantini MG, Goedert M. Identification of two distinct synucleins from human brain. FEBS Lett 1994; 345:27-32.
7. Clayton DF, George JM. Synucleins in synaptic plasticity and neurodegenerative disorders. J Neurosci Res 1999; 58:120-9.
8. Lavedan C. The synuclein family. Genome Res 1998; 8:871-80.
9. Lotharius J, Brundin P. Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. Hum Mol Genet 2002; 11:2395-407.
10. Di Rosa G, Puzzo D, Sant'Angelo A, Trinchese F, Arancio O. Alpha-synuclein: between synaptic function and dysfunction. Histol Histopathol 2003; 18:1257-66.
11. Neystat M, Lynch T, Przedborski S, Kholodilov N, Rzhetskaya M, Burke RE. Alpha-synuclein expression in substantia nigra and cortex in Parkinson's disease. Mov Disord 1999; 14:417-22.
12. Kingsbury AE, Daniel SE, Sangha H, Eisen S, Lees AJ, Foster OJ. Alteration in alpha-synuclein mRNA expression in Parkinson's disease. Mov Disord 2004; 19:162-70.
13. Abeliovich A, Schmitz Y, Farinas I, Choi-Lundberg D, Ho WH, Castillo PE, Shinsky N, Verdugo JM, Armanini M, Ryan A, Hynes M, Phillips H, Sulzer D, Rosenthal A. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 2000; 25:239-52.
14. Lee FJ, Liu F, Pristupa ZB, Niznik HB. Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 2001; 15:916-26.
15. Perez RG, Hastings TG. Could a loss of alpha-synuclein function put dopaminergic neurons at risk? J Neurochem 2004; 89:1318-24.
16. Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci U S A 1998; 95:6469-73.
17. Lansbury PT Jr, Brice A. Genetics of Parkinson's disease and biochemical studies of implicated gene products. Curr Opin Genet Dev 2002; 12:299-306.
18. Betarbet R, Sherer TB, Greenamyre JT. Ubiquitin-proteasome system and Parkinson's diseases. Exp Neurol 2005; 191:S17-27.
19. Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci U S A 1983; 80:4546-50.
20. Cuenca N, Herrero MT, Angulo A, de Juan E, Martinez-Navarrete GC, Lopez S, Barcia C, Martin-Nieto J. Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease. J Comp Neurol 2005; 493:261-73.
21. George JM. The synucleins. Genome Biol 2002; 3:REVIEWS3002.
22. Trojanowski JQ, Lee VM. Parkinson's disease and related synucleinopathies are a new class of nervous system amyloidoses. Neurotoxicology 2002; 23:457-60.
23. Kahle PJ, Neumann M, Ozmen L, Muller V, Jacobsen H, Schindzielorz A, Okochi M, Leimer U, van Der Putten H, Probst A, Kremmer E, Kretzschmar HA, Haass C. Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain. J Neurosci 2000; 20:6365-73.
24. Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, Takeda A, Sagara Y, Sisk A, Mucke L. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 2000; 287:1265-9.
25. Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL. Human alphasynuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc Natl Acad Sci U S A 2002; 99:8968-73.
26. Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P. alpha-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc Natl Acad Sci U S A 2002; 99:10813-8.
27. Bodis-Wollner I. Visual deficits related to dopamine deficiency in experimental animals and Parkinson's disease patients. Trends Neurosci 1990; 13:296-302.
28. Nguyen-Legros J, Harnois C, Di Paolo T, Simon A. The retinal dopamine system in Parkinson's disease. Clinical and Visual Science. 1993; 8:1-12.
29. Rodnitzky RL. Visual dysfunction in Parkinson's disease. Clin Neurosci 1998; 5:102-6.
30. Uc EY, Rizzo M, Anderson SW, Qian S, Rodnitzky RL, Dawson JD. Visual dysfunction in Parkinson disease without dementia. Neurology 2005; 65:1907-13.
31. Barcia C, Bautista V, Sanchez-Bahillo A, Fernandez-Villalba E, Navarro-Ruis JM, Barreiro AF, Poza Y Poza M, Herrero MT. Circadian determinations of cortisol, prolactin and melatonin in chronic methyl-phenyl-tetrahydropyridine-treated monkeys. Neuroendocrinology 2003; 78:118-28.
32. Cuenca N, Pinilla I, Sauve Y, Lund R. Early changes in synaptic connectivity following progressive photoreceptor degeneration in RCS rats. Eur J Neurosci 2005; 22:1057-72.
33. Rozen S, Skaletsky HJ. Primer3 on the WWW for general users and for biologist programmers. In: Misener S, Krawetz SA, editors. Bioinformatics methods and protocols. Totowa (NJ): Humana Press; 2000. p. 365-86.
34. Schulz-Key S, Hofmann HD, Beisenherz-Huss C, Barbisch C, Kirsch M. Ciliary neurotrophic factor as a transient negative regulator of rod development in rat retina. Invest Ophthalmol Vis Sci 2002; 43:3099-108.
35. Kolb H, Zhang L, Dekorver L, Cuenca N. A new look at calretinin-immunoreactive amacrine cell types in the monkey retina. J Comp Neurol 2002; 453:168-84.
36. Cuenca N, Deng P, Linberg KA, Lewis GP, Fisher SK, Kolb H. The neurons of the ground squirrel retina as revealed by immunostains for calcium binding proteins and neurotransmitters. J Neurocytol 2002; 31:649-66.
37. Wiedenmann B, Franke WW. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 1985; 41:1017-28.
38. Brandstatter JH, Lohrke S, Morgans CW, Wassle H. Distributions of two homologous synaptic vesicle proteins, synaptoporin and synaptophysin, in the mammalian retina. J Comp Neurol 1996; 370:1-10.
39. Von Kriegstein K, Schmitz F, Link E, Sudhof TC. Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. Eur J Neurosci 1999; 11:1335-48.
40. Surguchov A. Focus on Molecules: The synucleins: "When friends become foes". Exp Eye Res 2006, Oct 14; [Epub ahead of print].
41. Surguchov A, McMahan B, Masliah E, Surgucheva I. Synucleins in ocular tissues. J Neurosci Res 2001; 65:68-77.
42. Chandra S, Gallardo G, Fernandez-Chacon R, Schluter OM, Sudhof TC. Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 2005; 123:383-96.
43. Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT Jr. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 1996; 35:13709-15.
44. Davidson WS, Jonas A, Clayton DF, George JM. Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J Biol Chem 1998; 273:9443-9.
45. Murphy DD, Rueter SM, Trojanowski JQ, Lee VM. Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 2000; 20:3214-20.
46. Chandra S, Fornai F, Kwon HB, Yazdani U, Atasoy D, Liu X, Hammer RE, Battaglia G, German DC, Castillo PE, Sudhof TC. Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proc Natl Acad Sci U S A 2004; 101:14966-71.
47. Kivela T, Tarkkanen A, Virtanen I. Synaptophysin in the human retina and retinoblastoma. An immunohistochemical and Western blotting study. Invest Ophthalmol Vis Sci 1989; 30:212-9.
48. Mandell JW, Townes-Anderson E, Czernik AJ, Cameron R, Greengard P, De Camilli P. Synapsins in the vertebrate retina: absence from ribbon synapses and heterogeneous distribution among conventional synapses. Neuron 1990; 5:19-33.
49. Catsicas S, Catsicas M, Keyser KT, Karten HJ, Wilson MC, Milner RJ. Differential expression of the presynaptic protein SNAP-25 in mammalian retina. J Neurosci Res 1992; 33:1-9.
50. Hering H, Kroger S. Formation of synaptic specializations in the inner plexiform layer of the developing chick retina. J Comp Neurol 1996; 375:393-405.
51. Schmied R, Holtzman E. Involvement of the Golgi apparatus in sorting of materials to opposite ends of frog rod retinal photoreceptors. J Neurobiol 1989; 20:115-38.
52. Surguchov A, Palazzo RE, Surgucheva I. Gamma synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motil Cytoskeleton 2001; 49:218-28.
53. Gibbs D, Kitamoto J, Williams DS. Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein. Proc Natl Acad Sci U S A 2003; 100:6481-6.
54. Ueda K, Saitoh T, Mori H. Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. Biochem Biophys Res Commun 1994; 205:1366-72.
55. Duda JE, Shah U, Arnold SE, Lee VM, Trojanowski JQ. The expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases. Exp Neurol 1999; 160:515-22.
56. Feany MB, Bender WW. A Drosophila model of Parkinson's disease. Nature 2000; 404:394-8.