Monoamine oxidases - Activities, genotypes and the shaping of behaviour

Journal of Neural Transmission

Volumn 114, Issue 6, 2007, Pages 817-822

  Oreland, L ^a,b   Nilsson, K ^a   Damberg, M ^a   Hallman, J ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Behaviour; Genotype; Monoamine oxidase; Personality; Platelet

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; BIOLOGICAL FACTOR;

ALLELE; BEHAVIOR; CONFERENCE PAPER; CRIMINAL BEHAVIOR; ENZYME ACTIVITY; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; PREDICTION; PRIORITY JOURNAL; PSYCHOSOCIAL ENVIRONMENT;

ADOLESCENT; AGING; BRAIN; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MONOAMINE OXIDASE; SEX CHARACTERISTICS; SOCIAL BEHAVIOR DISORDERS;

EID: 34250813331     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0694-8     Document Type: Conference Paper

References (62)

1. MS Ansorge M Zhou A Lira R Hen JA Gingrich 2004 Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice Science 306 879 881
2. AJ Bennett KP Lesch A Heils JC Long JG Lorenz SE Shoaf M Champoux SJ Suomi MV Linnoila JD Higley 2002 Early experience and serotonin transporter gene variation interact to influence primate CNS function Mol Psychiatry 7 118 122
3. SM Brown E Peet SB Manuck DE Williamson RE Dahl RE Ferrell AR Hariri 2005 A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity Mol Psychiatry 10 884 888
4. T Canli K Omura BW Haas A Fallgater RT Constable KP Lesch 2005a Beyond affect: a role for genetic variation of the serotonin transporter in neural activation during a cognitive attention task Proc Natl Acad Sci USA 102 12224 12229
5. T Canli E Congdon L Gutknecht RT Constable KP Lesch 2005b Amygdala responsiveness is modulated by tryptophan hydroxylase-2 gene variation J Neural Transm 112 1479 1485
6. L Carrel HF Willard 2005 X-inactivation profile reveals extensive variability in X-linked gene expression in females Nature 434 400 404
7. A Caspi J McClay TE Moffitt J Mill J Martin IW Craig A Taylor R Poulton 2002 Role of genotype in the cycle of violence in maltreated children Science 297 851 854
8. A Caspi K Sugden TE Moffitt A Taylor IW Craig H Harrington J McClay J Mill J Martin A Braithwaite R Poulton 2003 Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science 301 386 389
9. M Cederblad L Oreland E Zachrisson 1992 Thrombocyte monoamine oxidase activity and behavior deviances in adolescence Dev Pharmacol Ther 18 184 190
10. P Costa-Mallen SN Kelada LG Costa H Checkoway 2005 Characterization of the in vitro transcriptional activity of polymorphic alleles of the human monoamine oxidase-B gene Neurosci Lett 383 171 175
11. M Damberg 2005 Transcription factor AP-2 and monoaminergic functions in the central nervous system J Neural Transm 112 1281 1296
12. RM Denney H Koch IW Craig 1999 Association between monoamine oxidase A activity in human male skin fibroblasts and genotype of the MAOA promoter-associated variable number tandem repeat Hum Genet 105 542 551
13. D Eensoo M Harro H Pullmann J Allik J Harro 2007 Association of traffic behavior with personality and platelet monoamine oxidase activity in schoolchildren J Adolesc Health 40 311 317
14. M Eriksson U Berggren C Fahlke J Engel J Balldin 2006 Platelet monoamine oxidase B (MAO-B) activity and its relationship to DL-fenfluramine-induced prolactin response in healthy men J Neural Transm 113 33 41
15. C Fahlke H Garpenstrand L Oreland SJ Suomi JD Higley 2002 Platelet monoamine oxidase activity in a nonhuman primate model of type 2 excessive alcohol consumption Am J Psychiatry 159 2107
16. DL Foley LJ Eaves B Wormley JL Silberg HH Maes J Kuhn B Riley 2004 Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder Arch Gen Psychiatry 61 738 744
17. CJ Fowler A Wiberg L Oreland J Marcusson B Winblad 1980 The effect of age on the activity and molecular properties of human brain monoamine oxidase J Neural Transm 49 1 20
18. T Furmark M Tillfors H Garpenstrand I Marteinsdottir B Langstrom L Oreland M Fredrikson 2004 Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia Neurosci Lett 362 189 192
19. R Gade D Muhleman H Blake J MacMurray P Johnson R Verde G Saucier DE Comings 1998 Correlation of length of VNTR alleles at the X-linked MAOA gene and phenotypic effect in Tourette syndrome and drug abuse Mol Psychiatry 3 50 60
20. H Garpenstrand J Ekblom K Forslund G Rylander L Oreland 2000 Platelet monoamine oxidase activity is related to MAOB intron 13 genotype J Neural Transm 107 523 530
21. P Gaspar O Cases L Maroteaux 2003 The developmental role of serotonin: news from mouse molecular genetics Nat Rev Neurosci 4 1002 1012
22. Göktürk C, Schultze S, von Knorring L, Oreland L, Hallman J (2006) Monoaminergic genotypes in a sample of female heavy alcohol and drug abusers. Manuscript in preparation
23. C Guindalini S Scivoletto RG Ferreira A Nishimura ML Zilberman MM Peluso M Zatz 2005 Association of MAO A polymorphism and alcoholism in Brazilian females Psychiatr Genet 15 141 144
24. AR Hariri SM Brown 2006 Serotonin Am J Psychiatry 163 12
25. AR Hariri VS Mattay A Tessitore B Kolachana F Fera D Goldman MF Egan DR Weinberger 2002 Serotonin transporter genetic variation and the response of the human amygdala Science 297 400 403
26. AR Hariri EM Drabant DR Weinberger 2006 Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing Biol Psychiatry 59 888 897
27. D Huizinga BC Haberstick A Smolen S Menard SE Young RP Corley MC Stallings J Grotpeter JK Hewitt 2006 Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase a genotype Biol Psychiatry 60 677 683
28. M Jansson S McCarthy PF Sullivan P Dickman B Andersson L Oreland M Schalling NL Pedersen 2005 MAOA haplotypes associated with thrombocyte-MAO activity BMC Genet 6 46
29. EG Jonsson N Norton JP Gustavsson L Oreland MJ Owen CG Sevall 2000 A promotor polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers J Psychiatr Res 34 239 244
30. KP Lesch 2005 Alcohol dependence and gene x environment interaction in emotion regulation: Is serotonin the link? Eur J Pharmacol 526 113 124
31. KP Lesch D Bengel A Heils SZ Sabol BD Greenberg S Petri J Benjamin CR Muller DH Hamer DL Murphy 1996 Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1527 1531
32. Malmberg K, Wargelius H-L, Lichtenstein P, Oreland L, Larsson J-O (2006) ADHD and Disruptive Behavior are related to MAO-B in platelets and polymorphisms in MAO-A, 5-HTT, Ap2β genes. In preparation
33. I Manor S Tyano E Mel J Eisenberg R Bachner-Melman M Kotler RP Ebstein 2002 Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA) Mol Psychiatry 7 626 632
34. SB Manuck JD Flory RE Ferrell KM Dent JJ Mann MF Muldoon 1999 Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene Biol Psychiatry 45 603 614
35. SB Manuck JD Flory RE Ferrell JJ Mann MF Muldoon 2000 A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity Psychiatr Res 95 9 23
36. A Meyer-Lindenberg JW Buckholtz B Kolachana A Hariri L Pezawas G Blasi A Wabnitz R Honea B Verchinski JH Callicott 2006 Neural mechanisms of genetic risk for impulsivity and violence in humans Proc Natl Acad Sci USA 103 6269 6274
37. TK Newman YV Syagailo CS Barr JR Wendland M Champoux M Graessle SJ Suomi JD Higley KP Lesch 2005 Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys Biol Psychiatry 57 167 172
38. KW Nilsson 2006 Gene-environment interaction in adolescent deviant behaviour Uppsala University Uppsala
39. KW Nilsson RL Sjoberg M Damberg PO Alm J Ohrvik J Leppert L Lindstrom L Oreland 2005 Role of the serotonin transporter gene and family function in adolescent alcohol consumption Alcohol Clin Exp Res 29 564 570
40. KW Nilsson RL Sjoberg M Damberg J Leppert J Öhrvik P-O Alm L Lindström L Oreland 2006 Role of MAO-A genotype & psychosocial factors in male adolescent criminal activity Biol Psychiatry 2 121 127
41. KW Nilsson RL Sjoberg H-L Wargelius J Leppert L Lindstrom L Oreland 2007 The MAO-A gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption Addiction 102 389 398
42. N Nordquist L Oreland 2006 Monoallelic expression of MAOA in skin fibroblasts Biochem Biophys Res Commun 348 763 767
43. L Oreland 2004 Platelet monoamine oxidase, personality and alcoholism: the rise, fall and resurrection Neurotoxicology 25 79 89
44. L Oreland J Hallman 1995 The correlation between platelet MAO activity and personality - a short review of findings and a discussion on possible mechanisms PH Yu KF Tipton AA Boulton Progress in brain research Elsevier Amsterdam
45. Oreland L, Shaskan EG (1983) Monoamine oxidase activity as a biological marker. Trends Pharmacol Sci: 339-341
46. L Oreland A Wiberg M Asberg L Traskman L Sjostrand P Thoren L Bertilsson G Tybring 1981 Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls Psychiatr Res 4 21 29
47. L Oreland Y Arai A Stenström CJ Fowler 1983 Monoamine oxidase activity and localization in the brain and the activity in relation to psychiatric disorders H Beckmann P Riederer Modern problems in pharmacopsychiatry Karger Basel 246 254
48. L Oreland J Hallman M Damberg 2004 Platelet MAO and personality - function and dysfunction Curr Med Chem 11 2007 2016
49. XM Ou K Chen JC Shih 2006 Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1 J Biol Chem 281 21512 21525
50. Paaver M, Nordquist N, Parik J, Harro M, Oreland L, Harro J (2006) The association of serotonergic markers platelet MAO activity and 5-HTTLPR with self-reported impulsivity and the speed and accuracy of visual information processing. Manuscript in preparation
51. A Parsian CR Cloninger R Sinha ZH Zhang 2003 Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysis Am J Med Genet 117B 46 50
52. L Passamonti F Fera A Magariello A Cerasa MC Gioia M Muglia G Nicoletti O Gallo L Provinciali A Quattrone 2006 Monoamine oxidase-a genetic variations influence brain activity associated with inhibitory control: new insight into the neural correlates of impulsivity Biol Psychiatry 59 334 340
53. L Pezawas A Meyer-Lindenberg EM Drabant BA Verchinski KE Munoz BS Kolachana MF Egan VS Mattay AR Hariri DR Weinberger 2005 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression Nat Neurosci 8 828 834
54. SZ Sabol S Hu D Hamer 1998 A functional polymorphism in the monoamine oxidase A gene promoter Hum Genet 103 273 279
55. T Saito HM Lachman L Diaz T Hallikainen J Kauhanen JT Salonen OP Ryynanen MK Karvonen E Syvalahti T Pohjalainen 2002 Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics Psychiatr Res 109 113 119
56. J Samochowiec KP Lesch M Rottmann M Smolka YV Syagailo O Okladnova H Rommelspacher G Winterer LG Schmidt T Sander 1999 Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism Psychiatr Res 86 67 72
57. JC Shih RF Thompson 1999 Monoamine oxidase in neuropsychiatry and behavior Am J Hum Genet 65 593 598
58. RL Sjoberg KW Nilsson N Nordquist J Ohrvik J Leppert L Lindstrom L Oreland 2006 Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene Int J Neuropsychopharmacol 9 443 449
59. RL Sjoberg KW Nilsson H-L Wargelius J Leppert L Lindstrom L Oreland 2007 Adolescent girls and criminal activity - role of MAO-A genotype and psychosocial factors Am J Med Genet 144 159 164
60. PM Whitaker-Azmitia 2005 Behavioral and cellular consequences of increasing serotonergic activity during brain development: a role in autism? Int J Dev Neurosci 23 75 83
61. G Zalsman YY Huang JM Harkavy-Friedman MA Oquendo SP Ellis JJ Mann 2005 Relationship of MAO-A promoter (u-VNTR) and COMT (V158M) gene polymorphisms to CSF monoamine metabolites levels in a psychiatric sample of caucasians: a preliminary report Am J Med Genet 132B 100 103
62. P Zill TC Baghai P Zwanzger C Schule D Eser R Rupprecht HJ Moller B Bondy M Ackenheil 2004 SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression Mol Psychiatry 9 1030 1036