Quantitative structure vasodilatory activity relationship - Synthesis and "in silico" and "in vitro" evaluation of resveratrol-coumarin hybrids

QSAR and Combinatorial Science

Volumn 26, Issue 3, 2007, Pages 317-332

  Vilar, Santiago ^a   Quezada, Elías ^a   Alcaide, Carlos ^a   Orallo, Francisco ^a   Santana, Lourdes ^a   Uriarte, Eugenio ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Coumarin; Linear discriminant analysis; QSAR; Resveratrol; Vasodilators

Indexed keywords

COMPUTATIONAL CHEMISTRY; DISCRIMINANT ANALYSIS; MOLECULAR GRAPHICS; SYNTHESIS (CHEMICAL);

ACTIVE COMPOUNDS; COUMARIN; IN-SILICO; IN-VITRO EVALUATION; LINEAR DISCRIMINANT ANALYZE; MOLECULAR DESCRIPTORS; QSAR; QUANTITATIVE STRUCTURES; THEORETICAL MODELING; VASODILATOR;

RESVERATROL;

ACECARBROMAL; ACENOCOUMAROL; ACETANILIDE; ACETOCHLOR; ACETOPHENAZINE; ALIZAPRIDE; AMETRYN; AMINOREX; BENFURODIL HEMISUCCINATE; BENORILATE; BEZITRAMIDE; BUPHENINE; CLORICROMEN; COUMARIN DERIVATIVE; DIPYRIDAMOLE; FENDILINE; HEXESTROL BIS(2 DIETHYLAMINOETHYL) ETHER; ISOXSUPRINE; MINOXIDIL; NIFEDIPINE; NORADRENALIN; PENTAERYTHRITYL TETRANITRATE; PRENYLAMINE; RESVERATROL; SALICYLIC ACID BENZYL ESTER; SULOCTIDIL; TOLAZOLINE; UNINDEXED DRUG; VINPOCETINE; ZOLERTINE;

ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; VASODILATATION;

RATTUS;

EID: 34250675344     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200630006     Document Type: Article

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