Pyruvate induces mitochondrial biogenesis by a PGC-1α-independent mechanism

American Journal of Physiology - Cell Physiology

Volumn 292, Issue 5, 2007, Pages

  Wilson, Leanne ^a   Yang, Qing ^a   Szustakowski, Joseph D ^a   Gullicksen, P Scott ^a   Halse, Reza ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Mitochondria; Muscle; Oxidative metabolism; Peroxisomal proliferator activator receptor coactivator 1

Indexed keywords

MESSENGER RNA; MITOCHONDRIAL PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PYRUVATE SODIUM; PYRUVIC ACID; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; BIOGENESIS; BREATHING RATE; CONTROLLED STUDY; GENE EXPRESSION; MITOCHONDRION; MOUSE; MUSCLE CELL; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ADAPTATION; ANIMAL; CELL RESPIRATION; DNA MICROARRAY; DRUG EFFECT; ENERGY METABOLISM; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MITOCHONDRIAL SIZE; MOUSE MUTANT; MUSCLE MITOCHONDRION; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PROTEIN SYNTHESIS; RNA INTERFERENCE;

ADENOVIRIDAE; MUS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL RESPIRATION; ENERGY METABOLISM; GENE EXPRESSION; GENE EXPRESSION PROFILING; MICE; MICE, KNOCKOUT; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL SIZE; MYOBLASTS, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PROTEIN BIOSYNTHESIS; PYRUVIC ACID; RNA INTERFERENCE; TRANS-ACTIVATORS;

EID: 34250664641     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00428.2006     Document Type: Article

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