A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis

Tuberculosis

Volumn 87, Issue 4, 2007, Pages 288-294

  Miguel Gómez, Luis ^a   Anaya, Juan Manuel ^a,b   Ramón Vilchez, José ^c   Cadena, Jose ^a   Hinojosa, Rosa ^a   Vélez, Luciano ^a   Angel Lopez Nevot, Miguel ^c   Martín, Javier ^d  

^a Unidad de Biología Celular y Molecular   (Colombia)

^b UNIVERSIDAD DEL ROSARIO   (Colombia)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^d CSIC   (Spain)

Author keywords

Genetics; Nitric oxide synthases; Tuberculosis

Indexed keywords

AMINO ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; TUBERCULIN;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; ENDEMIC DISEASE; FEMALE; GENE LOCATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; HUMAN; IMMUNOPATHOGENESIS; INFECTION RISK; LONG TERMINAL REPEAT; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SAMPLE SIZE; SHORT TANDEM REPEAT; SKIN TEST;

ADULT; COLOMBIA; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; SEROEPIDEMIOLOGIC STUDIES; TANDEM REPEAT SEQUENCES; TUBERCULOSIS, PULMONARY;

EID: 34250656205     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tube.2007.03.002     Document Type: Article

References (47)

1. Kwon O.J. The role of nitric oxide in the immune response of tuberculosis. J Korean Med Sci 12 (1997) 481-487
2. Lowenstein C.J., and Snyder S.H. Nitric oxide, a novel biologic messenger. Cell 70 (1992) 705-707
3. Moncada S. Nitric oxide in the vasculature: physiology and pathophysiology. Ann N Y Acad Sci 811 (1997) 60-67
4. MacMicking J.D., North R.J., LaCourse R., Mudgett J.S., Shah S.K., and Nathan C.F. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc Natl Acad Sci USA 94 (1997) 5243-5248
5. Greenberg S.S., Xie J., Kolls J., Mason C., and Didier P. Rapid induction of mRNA for nitric oxide synthase II in rat alveolar macrophages by intratracheal administration of Mycobacterium tuberculosis and Mycobacterium avium. Proc Soc Exp Biol Med 209 (1995) 46-53
6. Rich E.A., Torres M., Sada E., Finegan C.K., Hamilton B.D., and Toossi Z. Mycobacterium tuberculosis (MTB)-stimulated production of nitric oxide by human alveolar macrophages and relationship of nitric oxide production to growth inhibition of MTB. Tuber Lung Dis 78 (1997) 247-255
7. Rockett K.A., Brookes R., Udalova I., Vidal V., Hill A.V., and Kwiatkowski D. 1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun 66 (1998) 5314-5321
8. Nicholson S., Bonecini-Almeida Mda G., Lapa e Silva J.R., et al. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J Exp Med 183 (1996) 2293-2302
9. Kuo H.P., Wang C.H., Huang K.S., et al. Nitric oxide modulates interleukin-1beta and tumor necrosis factor-alpha synthesis by alveolar macrophages in pulmonary tuberculosis. Am J Respir Crit Care Med 161 (2000) 192-199
10. Wang C.H., Liu C.Y., Lin H.C., Yu C.T., Chung K.F., and Kuo H.P. Increased exhaled nitric oxide in active pulmonary tuberculosis due to inducible NO synthase upregulation in alveolar macrophages. Eur Respir J 11 (1998) 809-815
11. Facchetti F., Vermi W., Fiorentini S., et al. Expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions. Am J Pathol 154 (1999) 145-152
12. Choi H.S., Rai P.R., Chu H.W., Cool C., and Chan E.D. Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med 166 (2002) 178-186
13. Warpeha K.M., Xu W., Liu L., et al. Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy. Faseb J 13 (1999) 1825-1832
14. Michel D., Chatelain G., Herault Y., and Brun G. The long repetitive polypurine/polypyrimidine sequence (TTCCC)48 forms DNA triplex with PU-PU-PY base triplets in vivo. Nucleic Acids Res 20 (1992) 439-443
15. Xu G., and Goodridge A.G. Characterization of a polypyrimidine/polypurine tract in the promoter of the gene for chicken malic enzyme. J Biol Chem 271 (1996) 16008-16019
16. Motallebipour M., Rada-Iglesias A., Jansson M., and Wadelius C. The promoter of inducible nitric oxide synthase implicated in glaucoma based on genetic análisis and nuclear factor binding. Mol Vis 11 (2005) 950-957
17. De Vera M.E., Shapiro R.A., Nussler A.K., et al. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci USA 93 (1996) 1054-1059
18. Boutlis C.S., Hobbs M.R., Marsh R.L., et al. Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. Am J Trop Med Hyg 69 (2003) 569-573
19. Gonzalez-Gay M.A., Llorca J., Sanchez E., et al. Inducible but not endothelial nitric oxide synthase polymorphism is associated with susceptibility to rheumatoid arthritis in northwest Spain. Rheumatology (Oxford) 43 (2004) 1182-1185
20. Burgner D., Xu W., Rockett K., et al. Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet 352 (1998) 1193-1194
21. Bellamy R., and Hill A.V. A bi-allelic tetranucleotide repeat in the promoter of the human inducible nitric oxide synthase gene. Clin Genet 52 (1997) 192-193
22. Nunokawa Y., Ishida N., and Tanaka S. Promoter analysis of human inducible nitric oxide synthase gene associated with cardiovascular homeostasis. Biochem Biophys Res Commun 200 (1994) 802-807
23. Morris B.J., Markus A., Glenn C.L., Adams D.J., Colagiuri S., and Wang L. Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. J Mol Med 80 (2002) 96-104
24. Jamieson S.E., Miller E.N., Black G.F., et al. Evidence for a cluster of genes on chromosome 17q11-q21 controlling susceptibility to tuberculosis and leprosy in Brazilians. Genes Immun 5 (2004) 46-57
25. Blackwell J.M., Black G.F., Peacock C.S., et al. Immunogenetics of leishmanial and mycobacterial infections: the Belem Family Study. Philos Trans R Soc Lond B Biol Sci 352 (1997) 1331-1345
26. Chaparro P.E., Garcia I., Guerrero M.I., and Leon C.I. Situation of tuberculosis in Colombia. Biomedica 24 (2002) 102-114
27. Correa P.A., Gomez L.M., Cadena J., and Anaya J.M. Autoimmunity and tuberculosis. Opposite association with TNF polymorphism. J Rheumatol 32 (2005) 219-224
28. Arcos-Burgos M., and Muenke M. Genetics of population isolates. Clin Genet 61 (2002) 233-247
29. Bravo M.L., Valenzuela C.Y., and Arcos-Burgos O.M. Polymorphisms and phyletic relationships of the Paisa community from Antioquia (Colombia). Gene Geogr 10 (1996) 11-17
30. Lee E., and Holzman R.S. Evolution and current use of the tuberculin test. Clin Infect Dis 34 (2002) 365-370
31. Xu W., Liu L., Emson P.C., Harrington C.R., and Charles I.G. Evolution of a homopurine-homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene. Gene 204 (1997) 165-170
32. Weir B.S., and Hill W.G. Estimating F-statistics. Annu Rev Genet 36 (2002) 721-750
33. Xu W., Humphries S., Tomita M., et al. Survey of the allelic frequency of a NOS2A promoter microsatellite in human populations: assessment of the NOS2A gene and predisposition to infectious disease. Nitric Oxide 4 (2000) 379-383
34. Orozco G., Sanchez E., Lopez-Nevot M.A., et al. Inducible nitric oxide synthase promoter polymorphism in human brucellosis. Microbes Infect 5 (2003) 1165-1169
35. Miller E.N., Jamieson S.E., Joberty C., et al. Genome-wide scans for leprosy and tuberculosis susceptibility genes in Brazilians. Genes Immun 5 (2004) 63-67
36. Michel D., Chatelain G., Herault Y., and Brun G. The long repetitive polypurine/polypyrimidine sequence (TTCCC)48 forms DNA triplex with PU-PU-PY base triplets in vivo. Nucleic Acids Res 20 (1992) 439-443
37. Burgner D., Rockett K., Ackerman H., et al. Haplotypic relationship between SNP and microsatellite markers at the NOS2A locus in two populations. Genes Immun 4 (2003) 506-514
38. Kun J.F., Mordmuller B., Lell B., Lehman L.G., Luckner D., and Kremsner P.G. Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria. Lancet 351 (1998) 265-266
39. Johannesen J., Pociot F., Kristiansen O.P., Karlsen A.E., and Nerup J. No evidence for linkage in the promoter region of the inducible nitric oxide synthase gene (NOS2) in a Danish type 1 diabetes population. Genes Immun 1 (2000) 362-366
40. Martin J., Calzada J.E., and Nieto A. Inducible nitric oxide synthase (NOS2) gene polymorphism and parasitic diseases. Lancet 353 (1999) 72
41. Flores-Villanueva P.O., Ruiz-Morales J.A., Song C.H., et al. A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. J Exp Med 202 (2005) 1649-1658
42. Xu W., Liu L., Emson P., et al. The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies. Neuroreport 11 (2000) 297-299
43. Konno S., Hizawa N., Yamaguchi E., Jinushi E., and Nishimura M. (CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy. J Allergy Clin Immunol 108 (2001) 810-814
44. Oates J.C., Levesque M.C., Hobbs M.R., et al. Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in African-Americans. J Rheumatol 30 (2003) 60-67
45. Jagannath C., Actor J.K., and Hunter Jr. R.L. Induction of nitric oxide in human monocytes and monocyte cell lines by Mycobacterium tuberculosis. Nitric Oxide 2 (1998) 174-186
46. Wang C.H., Lin H.C., Liu C.Y., et al. Upregulation of inducible nitric oxide synthase and cytokine secretion in peripheral blood monocytes from pulmonary tuberculosis patients. Int J Tuberc Lung Dis 5 (2001) 283-291
47. Scanga C.A., Mohan V.P., Tanaka K., Alland D., Flynn J.L., and Chan J. The inducible nitric oxide synthase locus confers protection against aerogenic challenge of both clinical and laboratory strains of Mycobacterium tuberculosis in mice. Infect Immun 69 (2001) 7711-7717