(CCTTT)nrepeat polymorphism in the NOS2 gene promoter is associated with atopy

Journal of Allergy and Clinical Immunology

Volumn 108, Issue 5, 2001, Pages 810-814

  Konno, Satoshi ^a   Hizawa, Nobuyuki ^a   Yamaguchi, Etsuro ^a   Jinushi, Eisei ^a   Nishimura, Masaharu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Asthma; Atopy; Nitric oxide synthase 2 (NOS2)

Indexed keywords

ALLERGEN; CYTOSINE; IMMUNOGLOBULIN E; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; THYMIDINE; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ALLERGY; ARTICLE; ASTHMA; ATOPY; CHROMOSOME 17; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENOME; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; RISK FACTOR; TH1 CELL; TH2 CELL;

EID: 0035189070     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2001.119030     Document Type: Article

References (31)

1. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
2. Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter
3. Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria
4. Inducible nitric oxide synthase (NOS2) gene polymorphism and parasitic diseases
5. Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells
6. Altered immune responses in mice lacking inducible nitric oxide synthase
7. Suppression of cytokine production in T helper type 2 cells by nitric oxide in comparison with T helper type 1 cells
8. Nitric oxide in autoimmune disease: Cytotoxic or regulatory mediator?
9. Effects of nitric oxide on the induction and differentiation of Th1 cells
10. Modulation of autoimmune diseases by nitric oxide
11. A genome-wide search for asthma susceptibility loci in ethnically diverse populations
12. Genome screen for asthma and related phenotypes in the French EGEA study
13. Evolution of a homopurine-homopyrimidine pentanucleptide repeat sequence upstream of the human inducible nitric oxide synthase gene
14. nrepeat of NOS2A in diabetic re tinopathy
15. CCTTT-repeat polymorphism in the human NOS2-promoter confers low risk of diabetic nephropathy in type 1 diabetic patients
16. A common FCER1B gene promoter polymorphism influences total serum IgE levels in a Japanese population
17. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune disease
18. 48forms DNA triplex with PU-PU-PY base triplets in vivo
19. Environmental factors and primary T-cell sensitization to inhalant allergens in infancy: Reappraisal of the role of infections and air pollution
20. 2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood
21. Childhood environment and adult atopy: Results from the European Community Respiratory Health Survey
22. Childhood exposure to infection and risk of adult onset wheeze and atopy
23. Atopy influences exhaled nitric oxide levels in adult asthmatics
24. Early exposure to house-dust mite and cat allergens and development of childhood asthma: A cohort study
25. Induction of nitric oxide synthase in asthma
26. Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice
27. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma
28. A European study on the genetics of mite sensitization
29. A bi-allelic tetranucleotide repeat in the promoter of the human inducible nitric oxide synthase gene
30. Variants of NOSI, NOS2, and NOS3 genes in asthmatics