Inducible nitric oxide synthase polymorphism and fatal cerebral malaria

Lancet

Volumn 352, Issue 9135, 1998, Pages 1193-1194

  Burgner, David ^b   Xu, Weiming ^b   Rockett, Kirk ^b   Gravenor, Michael ^b   Charles, Ian G ^b   Hill, Adrian V ^b   Kwiatkowski, Dominic ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ARTICLE; BRAIN MALARIA; FATALITY; GABON; GAMBIA; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0032505641     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)60531-4     Document Type: Article

References (5)

1. 1 Clark IA, Rockett KA, Cowden WB. Possible central role of nitric oxide in conditions clinically similar to cerebral malaria. Lancet 1992; 340: 894-96.
2. 2 Anstey NM, Weinberg JB, Hassanali MY, et al. Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med 1996; 184: 557-67.
3. 3 Kun JFJ, Mordmüller B, Lell B, Lehman LG, Luckner D, Kremsner PG. Polymorphism in promoter region of inducible nitric oxide synthase and protection against malaria. Lancet 1998; 351: 265-66.
4. 4 Xu W, Liu L, Emson CP, Charles IG. Evolution of a homopurine-homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene. Gene 1997; 204: 165-70.
5. 5 Hill AV, Allsopp CE, Kwiatkowski D, et al. Common west African HLA antigens are associated with protection from severe malaria. Nature 1989; 352: 595-600.