Analysis of the human integrin α11 gene (ITGA11) and its promoter

Matrix Biology

Volumn 21, Issue 6, 2002, Pages 513-523

  Zhang, Wan Ming ^a   Popova, Svetlana N ^a   Bergman, Charlotta ^a   Velling, Teet ^a   Gullberg, Marion Kusche ^a   Gullberg, Donald ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Gene structure; Integrin alpha 11; Promoter analysis

Indexed keywords

INTEGRIN; INTEGRIN ALPHA11; LUCIFERASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CHROMOSOME 15; DNA FLANKING REGION; EXON; GENE STRUCTURE; MESENCHYME; MOLECULAR CLONING; MOLECULAR MECHANICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SEQUENCE ANALYSIS;

ALTERNATIVE SPLICING; BASE SEQUENCE; CLONING, MOLECULAR; EXONS; HUMANS; INTEGRIN ALPHA CHAINS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); TRANSCRIPTION INITIATION SITE; TUMOR CELLS, CULTURED;

EID: 0036774481     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(02)00054-9     Document Type: Article

References (46)

1. Armulik A., Nilsson I., von Heijne G., Johansson S. Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits. J. Biol. Chem. 274:1999;37030-37034.
2. Bengtsson T., Camper L., Schneller M., Lundgren-Åkerlund E. Characterization of the mouse integrin subunit alpha10 gene and comparison with its human homologue. Genomic structure, chromosomal localization and identification of splice variants. Matrix Biol. 20:2001;565-576.
3. Bienkowska J., Cruz M., Atiemo A., Handin R., Liddington R. The von Willebrand factor A3 domain does not contain a metal ion-dependent adhesion site motif. J. Biol. Chem. 272:1997;25162-25167.
4. Blackwell T.K., Weintraub H. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science. 250:1990;1104-1110.
5. Bray P.F. Integrin polymorphisms as risk factors for thrombosis. Thromb Haemost. 82:1999;337-344.
6. Bray P.F. Platelet glycoprotein polymorphisms as risk factors for thrombosis. Curr. Opin. Hematol. 7:2000;284-289.
7. Bray P.F., Shuman M.A. Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia. Blood. 75:1990;881-888.
8. Briesewitz R., Kern A., Smilenov L.B., David F.S., Marcantonio E.E. The membrane-cytoplasm interface of integrin alpha subunits is critical for receptor latency. Mol. Biol. Cell. 7:1996;1499-1509.
9. Brown D., Wagner D., Li X., Richardson J.A., Olson E.N. Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. Development. 126:1999;4317-4329.
10. Brown N.H. Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biol. 19:2000;191-201.
11. Camper L., Hellman U., Lundgren-Åkerlund E. Isolation, cloning, and sequence analysis of the integrin subunit α10, a β1-associated collagen binding integrin expressed on chondrocytes. J. Biol. Chem. 273:1998;20383-20389.
12. Corbi A.L., Garcia-Aguilar J., Springer T.A. Genomic structure of an integrin α subunit, the leukocyte p150,95 molecule. J. Biol. Chem. 265:1990;2782-2788.
13. Cserjesi P., Brown D., Ligon K.L., et al. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development. 121:1995;1099-1110.
14. de Melker A.A., Sonnenberg A. Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events. Bioessays. 21:1999;499-509.
15. Dickeson S.K., Santoro S.A. Ligand recognition by the I domain-containing integrins. Cell. Mol. Life Sci. 54:1998;556-566.
16. Emsley J., King S.L., Bergelson J.M., Liddington R.C. Crystal structure of the I domain from integrin α2β1. J. Biol. Chem. 272:1997;28512-28517.
17. Emsley J., Knight C.G., Farndale R.W., Barnes M.J., Liddington R.C. Structural basis of collagen recognition by integrin α2β1. Cell. 101:2000;47-56.
18. Fessler L.I., Nelson R.E., Fessler J.H. Drosophila extracellular matrix. Methods Enzymol. 245:1994;271-294.
19. Graner M.W., Bunch T.A., Baumgartner S., Kerschen A., Brower D.L. Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, ten-m, and D-laminin 2. J. Biol. Chem. 273:1998;18235-18241.
20. Gullberg D., Lundgren-Åkerlund E. Collagen-binding I domain integrins- what do they do? Prog. Histochem. Cytochem. 37:2002;3-54.
21. Hayashi Y.K., Chou F.-L., Engvall E., et al. Mutations in the integrin a7 gene cause congenital myopathy. Nat. Genet. 19:1998;94-97.
22. Hynes R.O. Integrins: versatility, modulation and signaling in cell adhesion. Cell. 69:1992;11-25.
23. Hynes R.O. Targeted mutations in cell adhesion genes: what have we learned from them? Dev. Biol. 180:1996;402-412.
24. Jaspers M., Marynen P., Aly M.S., Cuppens H., Hilliker C., Cassiman J.J. Localization of the gene encoding the α2 subunit of the human VLA-2 receptor to chromosome 5q23-31. Somat. Cell Mol. Genet. 17:1991;505-511.
25. Kophengnavong T., Michnowicz J.E., Blackwell T.K. Establishment of distinct MyoD, E2A and twist DNA binding specificities by different basic region-DNA conformations. Mol. Cell Biol. 20:2000;261-272.
26. Kritzik M., Savage B., Nugent D.J., Santoso S., Ruggeri Z.M., Kunicki T.J. Nucleotide polymorphisms in the α2 gene define multiple alleles that are associated with differences in platelet α2β1 density. Blood. 92:1998;2382-2388.
27. Laird P., Zidjerweld A., Linders K., Rudnicki M.A., Jaenisch R., Berns A. Simplified mammalian DNA isolation procedure. Nucleic Acid Res. 19:1991;4293.
28. Lefebvre V., Li P., de Crombrugghe B. A new long form of Sox5 (L-Sox5) Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. Embo J. 17:1998;5718-5733.
29. Lehnert K., Ni J., Leung E., et al. Cloning, sequence analysis and chromosomal localization of the novel human integrin α11 subunit (ITGA11). Genomics. 60:1999;179-187.
30. Lu J., Chang P., Richardson J.A., Gan L., Weiler H., Olson E.N. Inaugural article: the basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. Proc. Natl. Acad. Sci. USA. 97:2000;9525-9530.
31. Lu J., Richardson J.A., Olson E.N. Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech. Dev. 73:1998;23-32.
32. Maruyama K., Sugano S. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene. 138:1994;171-174.
33. Mykytyn K., Braun T., Carmi R., et al. Identification of the gene that, when mutated causes the human obesity syndrome BBS4. Nat. Genet. 28:2001;188-191.
34. Obata H., Hayashi K., Nishida W., et al. Smooth muscle cell phenotype-dependent transcriptional regulation of the α1 integrin gene. J. Biol. Chem. 272:1997;26643-26651.
35. Pulkkinen L., Uitto J. Mutation analysis and molecular genetics of epidermolysis bullosa. Matrix Biol. 18:1999;29-42.
36. Rich R.L., Deivanayagam C.C., Owens R.T., et al. Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors α1β1 integrin and Staphylococcus aureus cna MSCRAMM. J. Biol. Chem. 274:1999;24906-24913.
37. Seymour A.B., Yanak B.L., O'Brien E.P., et al. An integrated genetic map of the pearl locus of mouse chromosome 13. Genome Res. 6:1996;538-544.
38. Slonim D., Kruglyak L., Stein L., Lander E. Building human genome maps with radiation hybrids. J. Comput. Biol. 4:1997;487-504.
39. Springer T.A. Folding of the N-terminal ligand-binding region of integrin α-subunits into a β-propeller domain. Proc. Natl. Acad. Sci. USA. 94:1997;65-72.
40. Tiger C.-F., Fougerousse F., Grundström G., Velling T., Gullberg D. α11β1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal non-muscle cells. Dev. Biol. 237:2001;116-129.
41. Tulla M., Pentikainen O.T., Viitasalo T., et al. Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I and alpha 10I domains. J. Biol. Chem. 276:2001;48206-48212.
42. Velling T., Kusche-Gullberg M., Sejersen T., Gullberg D. cDNA cloning and chromosomal localization of human α11 integrin. A collagen-binding, I domain-containing β1-associated integrin α-chain present in muscle tissues. J. Biol. Chem. 274:1999;25735-25742.
43. Xiong J.P., Stehle T., Diefenbach B., et al. Crystal structure of the extracellular segment of integrin αVβ3. Science. 294:2001;339-345.
44. Ziober B.L., Kramer R.H. Identification and characterization of the cell type-specific and developmentally regulated α7 integrin gene promoter. J. Biol. Chem. 271:1996;22915-22922.
45. Zutter M.M., Ryan E.E., Painter A.D. Binding of phosphorylated Sp1 protein to tandem Sp1 binding sites regulates α2 integrin gene core promoter activity. Blood. 90:1997;678-689.
46. Zutter M.M., Santoro S.A., Painter A.S., Tsung Y.L., Gafford A. The human α2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression. J. Biol. Chem. 269:1994;463-469.