Elevated levels of endogenous apoptotic DNA and IFN-α in complement C4-deficient mice: Implications for induction of systemic lupus erythematosus

European Journal of Immunology

Volumn 37, Issue 6, 2007, Pages 1702-1709

  Finke, Doreen ^a   Randers, Katharina ^a   Hoerster, Robert ^a   Hennig, Holger ^a   Zawatzky, Rainer ^b   Marion, Tony ^c   Brockmann, Christian ^a   Klempt Giessing, Katja ^a   Jacobsen, Kirsten ^a   Kirchner, Holger ^a   Goerg, Siegfried ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Apoptotic DNA; Complement; Erythematosus; IFN ; Systemic lupus

Indexed keywords

ALPHA INTERFERON; COMPLEMENT COMPONENT C4; DNA; NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; DNA DETERMINATION; DNA ISOLATION; GENE TARGETING; HUMORAL IMMUNITY; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, CD11B; ANTIGENS, CD45; APOPTOSIS; COMPLEMENT C4; DNA; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOGLOBULIN M; IN SITU NICK-END LABELING; INTERFERON TYPE II; INTERFERON-ALPHA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN;

EID: 34250639437     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636719     Document Type: Article

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